The DOI matches its Crossref record; 143 of the 143 references it cites were found in a registry or an index.
Regulation of alveolar macrophage death in acute lung inflammation
Open accessAbstract
Acute lung injury (ALI) and its severe form, known as acute respiratory distress syndrome (ARDS), are caused by direct pulmonary insults and indirect systemic inflammatory responses that result from conditions such as sepsis, trauma, and major surgery. The reciprocal influences between pulmonary and systemic inflammation augments the inflammatory process in the lung and promotes the development of ALI. Emerging evidence has revealed that alveolar macrophage (AM) death plays important roles in the progression of lung inflammation through its influence on other immune cell populations in the lung. Cell death and tissue inflammation form a positive feedback cycle, ultimately leading to exaggerated inflammation and development of disease. Pharmacological manipulation of AM death signals may serve as a logical therapeutic strategy for ALI/ARDS. This review will focus on recent advances in the regulation and underlying mechanisms of AM death as well as the influence of AM death on the development of ALI.
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Gut-Lung Crosstalk in Sepsis-Induced Acute Lung Injury
Zhou, X., & Liao, Y. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.779620 · Cited by 153
Regdon, Z., Robaszkiewicz, A., Kovács, K., Rygielska, Ż., Hegedűs, C., Bodoor, K., Szabó, É., & Virág, L. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.11.034 · Cited by 59
Metadata
- Authors
- Fan, E. K. Y., & Fan, J.
- Venue
- Respiratory Research
- Published
- 2018-03-27
- Volume
- 19
- Issue
- 1
- Pages
- 50-50
- ISSN
- 1465-9921 (ISSN-L)
- 1465-993X
- OpenAlex
- W2804172422
- Cited by
- 313
- References
- 143
- FWCI
- 6.51
- Type
- journal article
- Language
- en
- Open access
- gold
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