MicroRNA-122 in human cancers: from mechanistic to clinical perspectives
Open accessAbstract
MicroRNAs (miRNAs) are endogenous short non-coding RNAs that can regulate the expression of target genes post-transcriptionally and interact with mRNA-coding genes. MiRNAs play vital roles in many biological functions, and abnormal miRNA expression has been linked to various illnesses, including cancer. Among the miRNAs, miR-122, miR-206, miR-21, miR-210, miR-223, and miR-424 have been extensively studied in various cancers. Although research in miRNAs has grown considerably over the last decade, much is yet to be discovered, especially regarding their role in cancer therapies. Several kinds of cancer have been linked to dysregulation and abnormal expression of miR-122, indicating that miR-122 may serve as a diagnostic and/or prognostic biomarker for human cancer. Consequently, in this review literature, miR-122 has been analyzed in numerous cancer types to sort out the function of cancer cells miR-122 and enhance patient response to standard therapy.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The three selected miRNAs-hsa-miR-122-5p, hsa-let-7a-5p, and hsa-miR-26a-5p-provide complementary and comprehensive coverage of almost all critical genes associated with the MAPK signaling pathway.
“From this analysis, we selected the three abundant miRNAs-hsa-miR-122-5p, hsa-let-7a-5p, and hsa-miR26a-5p-based on their complementary and comprehensive coverage of almost all the critical genes associated with the MAPK signaling pathway 27-33 as analyzed using miRTarBase version 8.0 and TarBase v8.0 integrated within miRNet (Figure S1).”
From rAAV-mediated Multi-miRNA Delivery Targeting MAPK Pathway Suppresses Laser-induced Choroidal Neovascularization in Mice (2026) · cites this paper as [33]
The section “Mechanism of miR-122 in human cancers > Reproductive system” reports that miR-122-5p acts through MAPK signaling in triple-negative breast cancer. It does not assess the three-miRNA combination or show that they collectively cover almost all critical MAPK-pathway genes; the citing sentence describes that coverage as the citing authors’ own analysis. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
7 retracted
Sun, Y., Jin, J., Mi, W., Hao-Wu, Zhang, S., Meng, Q., & Zhang, S. (2017) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.3727/096504017x14934860122864 · Cited by 60 · see citing works
RetractedRETRACTED: MiR-211 plays a dual role in cancer development: From tumor suppressor to tumor enhancer
Shirvani, H., Ghanavi, J., Aliabadi, A., Mousavinasab, F., Talebi, M., Majidpoor, J., Najafi, S., Miryounesi, S. M., & Zarch, S. M. A. (2022) · Cellular Signalling · doi:10.1016/j.cellsig.2022.110504 · Cited by 48 · see citing works
Self-citationRetractedRETRACTED: MiR-122 Induces Radiosensitization in Non-Small Cell Lung Cancer Cell Line
Ma, D., Jia, H., Qin, M., Dai, W., Wang, T., Liang, E., Dong, G., Wang, Z., Zhang, Z., & Feng, F. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160922137 · Cited by 47 · see citing works
RetractedmiR-122 Inhibits Hepatocarcinoma Cell Progression by Targeting LMNB2
Li, X., Yang, H., & Yang, T. (2019) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.3727/096504019x15615433287579 · Cited by 40 · see citing works
RetractedMicroRNA-122 inhibits proliferation and invasion in gastric cancer by targeting CREB1.
Rao, M., Zhu, Y., Zhou, Y., Cong, X., & Li, F. (2017) · Europe PMC (PubMed Central) · Cited by 33 · see citing works
RetractedRETRACTED: MiR-122 Promotes the Development of Colon Cancer by Targeting ALDOA In Vitro
Li, H., Zhang, X., Jin, Z. Y., Yin, T., Duan, C., Sun, J., Xiong, R., & Li, Z. (2019) · Technology in Cancer Research & Treatment · doi:10.1177/1533033819871300 · Cited by 28 · see citing works
RetractedRETRACTED: Non-coding RNA in SARS-CoV-2: Progress toward therapeutic significance
Shirvani, H., Jafari, H., Moravveji, S. S., Faranghizadeh, F. A., Talebi, M., Ghanavi, J., Esfandi, F., Najafi, S., Moghadam, M. N., Farnia, P., et al. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.09.105 · Cited by 20 · see citing works
Self-citationRetractedA microRNA expression signature of human solid tumors defines cancer gene targets
Volinia, S., Calin, G. A., Liu, C.-G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510565103 · Cited by 5,697 · see citing works
Yang (2021) · doi:10.1038/s41598-020-79139-8 · Cited by 5,035 · see citing works
The role of MicroRNAs in human cancer
Peng, Y., & Croce, C. M. (2016) · Signal Transduction and Targeted Therapy · doi:10.1038/sigtrans.2015.4 · Cited by 2,507 · see citing works
Fong, M. Y., Zhou, W., Liu, L., Alontaga, A. Y., Chandra, M., Ashby, J., Chow, A., O’Connor, S. T. F., Li, S., Chin, A. R., et al. (2015) · Nature Cell Biology · doi:10.1038/ncb3094 · Cited by 1,118 · see citing works
Coulouarn, C., Factor, V. M., Andersen, J. B., Durkin, M. E., & Thorgeirsson, S. S. (2009) · Oncogene · doi:10.1038/onc.2009.211 · Cited by 733 · see citing works
Lou, G., Song, X., Yang, F., Wu, S., Wang, J., Chen, Z., & Liu, Y. (2015) · Journal of Hematology & Oncology · doi:10.1186/s13045-015-0220-7 · Cited by 700 · see citing works
Wang, X., Zhang, H., Yang, H., Bai, M., Ning, T., Deng, T., Liu, R., Fan, Q., Zhu, K., Li, J., et al. (2020) · Molecular Oncology · doi:10.1002/1878-0261.12629 · Cited by 492 · see citing works
Liver-specific microRNA-122: Biogenesis and function
Jopling, C. L. (2012) · RNA Biology · doi:10.4161/rna.18827 · Cited by 415 · see citing works
Long, J.-K., Dai, W., Zheng, Y.-W., & Zhao, S.-P. (2019) · Molecular Medicine · doi:10.1186/s10020-019-0085-2 · Cited by 281 · see citing works
MiR-122 Inhibits Cell Proliferation and Tumorigenesis of Breast Cancer by Targeting IGF1R
Wang, B., Wang, H., & Yang, Z. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047053 · Cited by 169 · see citing works
Cheng, D., Deng, J., Zhang, B., He, X., Meng, Z., Li, G., Ye, H., Zheng, S., Wei, L., Deng, X., et al. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.08.055 · Cited by 167 · see citing works
Xu, Y., Huang, J., Ma, L., Shan, J., Shen, J., Yang, Z., Liu, L., Luo, Y., Yao, C., & Qian, C. (2015) · Cancer Letters · doi:10.1016/j.canlet.2015.11.034 · Cited by 165 · see citing works
From structures to functions: insights into exosomes as promising drug delivery vehicles
Ren, J., He, W., Zheng, L., & Duan, H. (2016) · Biomaterials Science · doi:10.1039/c5bm00583c · Cited by 161 · see citing works
Su, R., Cao, S., Ma, J., Liu, Y., Liu, X., Zheng, J., Chen, J., Liu, L., Cai, H., Li, Z., et al. (2017) · Molecular Cancer · doi:10.1186/s12943-017-0737-1 · Cited by 153 · see citing works
Ma, L., Liu, J., Shen, J., Liu, L., Wu, J., Li, W., Luo, J., Chen, Q., & Qian, C. (2010) · Cancer Biology & Therapy · doi:10.4161/cbt.9.7.11267 · Cited by 148 · see citing works
Regulation and biological function of the liver-specific miR-122
Lewis, A., & Jopling, C. L. (2010) · Biochemical Society Transactions · doi:10.1042/bst0381553 · Cited by 139 · see citing works
Active glycolytic metabolism in CD133(+) hepatocellular cancer stem cells: regulation by MIR-122
Song, K., Kwon, H., Han, C., Zhang, J., Dash, S., Lim, K., & Wu, T. (2015) · Oncotarget · doi:10.18632/oncotarget.5812 · Cited by 125 · see citing works
Yin, Z., Zhou, Y., Ma, T.-T., Chen, S., Shi, N., Zou, Y.-P., Hou, B., & Zhang, C. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15125 · Cited by 116 · see citing works
Recent trends in targeting miRNAs for cancer therapy
Shah, V., & Shah, J. (2020) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.13351 · Cited by 113 · see citing works
Oleanolic acid suppresses the proliferation of lung carcinoma cells by miR-122/Cyclin G1/MEF2D axis
Zhao, X., Liu, M., & Li, D. (2014) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-014-2228-7 · Cited by 112 · see citing works
Sun, L., Liu, X., Pan, B., Hu, X., Zhu, Y., Su, Y., Guo, Z., Zhang, G., Xu, M., Xu, X., et al. (2019) · Journal of Cancer · doi:10.7150/jca.33022 · Cited by 110 · see citing works
Plasma miR‐122 and miR‐200 family are prognostic markers in colorectal cancer
Maierthaler, M., Benner, A., Hoffmeister, M., Surowy, H., Jansen, L., Knebel, P., Chang-Claude, J. C., Brenner, H., & Burwinkel, B. (2016) · International Journal of Cancer · doi:10.1002/ijc.30433 · Cited by 103 · see citing works
Serum miR-122-5p and miR-206 expression: non-invasive prognostic biomarkers for renal cell carcinoma
Heinemann, F. G., Tolkach, Y., Deng, M. C.-H. K., Schmidt, D. H., Perner, S., Kristiansen, G., Müller, S. C., & Ellinger, J. (2018) · Clinical Epigenetics · doi:10.1186/s13148-018-0444-9 · Cited by 97 · see citing works
Resveratrol chemosensitizes adriamycin‐resistant breast cancer cells by modulating miR‐122‐5p
Zhang, W., Jiang, H., Chen, Y., & Ren, F. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28910 · Cited by 95 · see citing works
Chen, Q., Ge, X., Zhang, Y., Xia, H., Yuan, D., Tang, Q., Chen, L., PANG, X., Leng, W., & Bi, F. (2014) · Oncology Reports · doi:10.3892/or.2014.3004 · Cited by 94 · see citing works
MiR-122-5p inhibits cell migration and invasion in gastric cancer by down-regulating DUSP4
Xu, X., Gao, F., Wang, J., Tao, L., Ye, J., Li, D., Ji, W., & Chen, X. (2018) · Cancer Biology & Therapy · doi:10.1080/15384047.2018.1423925 · Cited by 87 · see citing works
Pan, C., Wang, X., Shi, K., Zheng, Y., Li, J., Chen, Y., Jin, L., & Pan, Z. (2016) · PLoS ONE · doi:10.1371/journal.pone.0152090 · Cited by 83 · see citing works
Nanoparticle Delivery of miR-122 Inhibits Colorectal Cancer Liver Metastasis
Sendi, H., Yazdimamaghani, M., Hu, M., Sultanpuram, N., Wang, J., Moody, A. S., McCabe, E., Zhang, J., Graboski, A. L., Li, L., et al. (2021) · Cancer Research · doi:10.1158/0008-5472.can-21-2269 · Cited by 81 · see citing works
Zeinali, F., Zarch, S. M. A., Jahan-Mihan, A., Kalantar, S. M., Mehrjardi, M. Y. V., Fallahzadeh, H., Hosseinzadeh, M., Rahmanian, M., & Mozaffari–Khosravi, H. (2021) · PLoS ONE · doi:10.1371/journal.pone.0251697 · Cited by 77 · see citing works
MiR-122 targets VEGFC in bladder cancer to inhibit tumor growth and angiogenesis.
Wang, Y., Xing, Q., Liu, X., Guo, Z., Li, C., & Sun, G. (2016) · Europe PMC (PubMed Central) · Cited by 76 · see citing works
Nanoparticle-Based Delivery of Tumor Suppressor microRNA for Cancer Therapy
O’Neill, C. P., & Dwyer, R. (2020) · Cells · doi:10.3390/cells9020521 · Cited by 75 · see citing works
Perez‐Añorve, I. X., la Rosa, C. H. G.-D., Soto‐Reyes, E., Beltrán‐Anaya, F. O., Moral-Hernández, Ó. D., Salgado-Albarrán, M., Angeles‐Zaragoza, O., González-Barrios, J. A., Landero‐Huerta, D. A., Chávez‐Saldaña, M., et al. (2019) · Molecular Oncology · doi:10.1002/1878-0261.12483 · Cited by 72 · see citing works
Najafi, S., Khatami, S. H., Khorsand, M., Jamali, Z., Shabaninejad, Z., Moazamfard, M., Majidpoor, J., Zarch, S. M. A., & Movahedpour, A. (2022) · Experimental Cell Research · doi:10.1016/j.yexcr.2022.113294 · Cited by 72 · see citing works
Self-citationBarajas, J. M., Reyes, R., Guerrero, M. J., Jacob, S. T., Motiwala, T., & Ghoshal, K. (2018) · Scientific Reports · doi:10.1038/s41598-018-27358-5 · Cited by 71 · see citing works
Zhang, H., Zhang, F., Li, H., Liu, Y., Du, G.-Y., & Huang, Y. (2016) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2016.03.031 · Cited by 70 · see citing works
Li, C., Qin, F., Wang, W., Ni, Y., Gao, M., Guo, M., & Sun, G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312866 · Cited by 69 · see citing works
The Role of the Liver-Specific microRNA, miRNA-122 in the HCV Replication Cycle
Kunden, R. D., Khan, J. Q., Ghezelbash, S., & Wilson, J. A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165677 · Cited by 68 · see citing works
The association of the expression of miR-122-5p and its target ADAM10 with human breast cancer
Ergün, S., Ulaşlı, M., İğci, Y. Z., İğci, M., Kırkbeş, S., Borazan, E., Balik, A. A., Yumrutaş, Ö., Camcı, C., Çakmak, E. A., et al. (2014) · Molecular Biology Reports · doi:10.1007/s11033-014-3793-2 · Cited by 66 · see citing works
Cao, F., & Yin, L. (2018) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2018.10.009 · Cited by 63 · see citing works
MiR‐122 inhibits epithelial mesenchymal transition by regulating P4HA1 in ovarian cancer cells
Duan, Y., Dong, Y., Dang, R., Hu, Z., Yang, Y., Hu, Y., & Cheng, J. (2018) · Cell Biology International · doi:10.1002/cbin.11052 · Cited by 63 · see citing works
Wang, Z., & Wang, X. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.29188 · Cited by 60 · see citing works
Differential TGFβ pathway targeting by miR-122 in humans and mice affects liver cancer metastasis
Yin, S., Fan, Y., Zhang, H., Zhao, Z., Hao, Y., Li, J., Sun, C., Yang, J., Yang, Z., Yang, X. Y., et al. (2016) · Nature Communications · doi:10.1038/ncomms11012 · Cited by 59 · see citing works
Loosen, S. H., Lurje, G., Wiltberger, G. J., Vucur, M., Koch, A. H., Kather, J. N., Paffenholz, P., Tacke, F., Ulmer, T. F., Trautwein, C., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0210944 · Cited by 59 · see citing works
miR‐122 promotes metastasis of clear‐cell renal cell carcinoma by downregulating Dicer
Yang, F., Ma, X., Li, H., Gao, Y., Huang, Q., Zhang, Y., Bao, X., Du, Q., Luo, G., Liu, K., et al. (2017) · International Journal of Cancer · doi:10.1002/ijc.31050 · Cited by 59 · see citing works
Okuyama, S., Marusawa, H., Matsumoto, T., Ueda, Y., Matsumoto, Y. M., Endo, Y., Takai, A., & Chiba, T. (2011) · International Journal of Cancer · doi:10.1002/ijc.26114 · Cited by 58 · see citing works
Yin, W., Xu, J., Li, C., Dai, X., Wu, T., & Wen, J. (2020) · OncoTargets and Therapy · doi:10.2147/ott.s238338 · Cited by 57 · see citing works
Recent insights into the roles of circular RNAs in human brain development and neurologic diseases
Najafi, S., Zarch, S. M. A., Majidpoor, J., Pordel, S., Aghamiri, S., Rasul, M. F., Asemani, Y., Vakili, O., Mohammadi, V., Movahedpour, A., et al. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.11.166 · Cited by 55 · see citing works
Self-citationGao, Z., Wang, Q., Ji, M., Guo, X., Li, L., & Su, X. (2021) · Journal of Translational Medicine · doi:10.1186/s12967-021-02872-9 · Cited by 55 · see citing works
Lian, J.-H., Wang, W., Wang, J., Zhang, Y., & Li, Y. (2013) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2013.14.9.5017 · Cited by 53 · see citing works
miR-122/Wnt/β-catenin regulatory circuitry sustains glioma progression
Wang, G., Zhao, Y., & Zheng, Y. (2014) · Tumor Biology · doi:10.1007/s13277-014-2089-4 · Cited by 49 · see citing works
Xu, Z., Liu, G., Zhang, M., Zhang, Z., Jia, Y., Peng, L., Zhu, Y., Hu, J., Huang, R., & Sun, X. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000492702 · Cited by 49 · see citing works
Long intergenic noncoding RNA 01296 aggravates gastric cancer cells progress through miR-122/MMP-9
Qin, Q.-H., Yin, Z., Li, Y., Wang, B., & Zhang, M. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.10.066 · Cited by 48 · see citing works
miRNA ‐122‐5p in POI ovarian‐derived exosomes promotes granulosa cell apoptosis by regulating BCL9
Zhang, X., Zhang, R., Hao, J., Huang, X., Liu, M., Lv, M., Su, C., & Mu, Y. (2022) · Cancer Medicine · doi:10.1002/cam4.4615 · Cited by 48 · see citing works
MiR-122 Targets SerpinB3 and Is Involved in Sorafenib Resistance in Hepatocellular Carcinoma
Turato, C., Fornari, F., Pollutri, D., Fassan, M., Quarta, S., Villano, G., Ruvoletto, M., Bolondi, L., Gramantieri, L., & Pontisso, P. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8020171 · Cited by 47 · see citing works
Zhang, Y., & Tang, L. (2017) · Cancer Cell International · doi:10.1186/s12935-017-0480-0 · Cited by 46 · see citing works
Gao, L., Chen, X., Wang, Y., & Zhang, J. (2020) · OncoTargets and Therapy · doi:10.2147/ott.s236359 · Cited by 46 · see citing works
Dai, C., Zhang, Y., Xu, Z., & Jin, M. (2020) · Cancer Cell International · doi:10.1186/s12935-020-01185-z · Cited by 46 · see citing works
Meng, L., Chen, Z., Jiang, Z., Huang, T., Hu, J., Luo, P.-Q., Zhang, H., Huang, M., Huang, L., Chen, Y., et al. (2019) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmz141 · Cited by 45 · see citing works
Exosomal miR-122-5p inhibits tumorigenicity of gastric cancer by downregulating GIT1
Jiao, Y., Zhang, L., Li, J., He, Y., Zhang, X., & Li, J. (2021) · The International Journal of Biological Markers · doi:10.1177/1724600821990677 · Cited by 44 · see citing works
Cui, K., Jin, S., Du, Y., Yu, J., Han, F., Fan, Q., & Ma, W. (2019) · Cancer Cell International · doi:10.1186/s12935-019-0922-y · Cited by 43 · see citing works
MicroRNA-206 in human cancer: Mechanistic and clinical perspectives.
Khasraghi, L. B., Nouri, M., Vazirzadeh, M., Hashemipour, N., Talebi, M., Zarch, F. A., Majidpoor, J., Kalhor, K., Farnia, P., Najafi, S., et al. (2022) · Cellular Signalling · doi:10.1016/j.cellsig.2022.110525 · Cited by 42 · see citing works
Self-citationMolecular biomarkers in diabetes mellitus (DM)
Zarch, S. M. A., Tezerjani, M. D., Talebi, M., & Mehrjardi, M. Y. V. (2020) · Medical Journal of the Islamic Republic of Iran · doi:10.47176/mjiri.34.28 · Cited by 41 · see citing works
Uen, Y., Wang, J.-W., Wang, C., Jhang, Y., Chung, J.-Y., Tseng, T., Sheu, M., & Lee, S.-C. (2018) · Oncotarget · doi:10.18632/oncotarget.25589 · Cited by 41 · see citing works
Chandimali, N., Huynh, D. L., Zhang, J., Lee, J. C., Yu, D., Jeong, D. K., & Kwon, T. (2018) · Cancer Gene Therapy · doi:10.1038/s41417-018-0050-1 · Cited by 41 · see citing works
Ding, F., Gao, B., Wu, X., Gong, C., Wang, W., & Zhang, S.-M. (2019) · FEBS Open Bio · doi:10.1002/2211-5463.12730 · Cited by 41 · see citing works
Progress toward molecular therapy for diabetes mellitus: A focus on targeting inflammatory factors
Dehghan, M., Ghorbani, F., Najafi, S., Ravaei, N., Karimian, M., Kalhor, K., Movafagh, A., & Zarch, S. M. A. (2022) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2022.109945 · Cited by 40 · see citing works
Self-citationGao, H., Qin, H., Sha, J., Jiang, C., Gao, X., Qu, L., Xu, T., Yan, H., & Qiyu, J. (2015) · OncoTargets and Therapy · doi:10.2147/ott.s91696 · Cited by 40 · see citing works
Yuan, Y., Zhang, Y., Liu, B., Wu, H., Kang, Y., Li, M., Zeng, X. A., He, N., & Zhang, G. (2015) · Journal of Nanobiotechnology · doi:10.1186/s12951-015-0070-z · Cited by 37 · see citing works
Kong, L., Wu, Q., Zhao, L., Ye, J., Li, N., & Yang, H. (2019) · Cell Cycle · doi:10.1080/15384101.2019.1593647 · Cited by 37 · see citing works
Wang, S., Zheng, W., Ji, A., Zhang, D., & Zhou, M. (2019) · Cancer Management and Research · doi:10.2147/cmar.s225742 · Cited by 36 · see citing works
miR-122 inhibits cancer cell malignancy by targeting PKM2 in gallbladder carcinoma
Lu, W., Zhang, Y., Zhou, L., Wang, X., Mu, J., Jiang, L., Hu, Y., Dong, P., & Liu, Y. (2015) · Tumor Biology · doi:10.1007/s13277-015-4308-z · Cited by 36 · see citing works
Hua, Y., Zhu, Y., Zhang, J., Zhu, Z., Ning, Z., Chen, H., Liu, L., Chen, Z., & Meng, Z. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000495832 · Cited by 36 · see citing works
Xiong, Q., Bai, Y., Shi, R., Wang, J., Xu, W., Zhang, M., & Song, T. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.03.026 · Cited by 35 · see citing works
Pei, Z., Zhang, Z. G., Hu, A., Yang, F., & Gai, Y. (2017) · Die Pharmazie · doi:10.31083/ph.2017.6404 · Cited by 34 · see citing works
Dehghani, M., Zarch, S. M. A., Mehrjardi, M. Y. V., Nazari, M., Babakhanzadeh, E., Ghadimi, H., Zeinali, F., & Talebi, M. (2020) · Endocrinología Diabetes y Nutrición · doi:10.1016/j.endinu.2019.09.009 · Cited by 33 · see citing works
Major miRNA Involved in Insulin Secretion and Production in Beta-Cells
Zarch, S. M. A., Khodadadian, A., Karimi‐Nazari, E., Nazari, M., & Babakhanzadeh, E. (2020) · International Journal of General Medicine · doi:10.2147/ijgm.s249011 · Cited by 33 · see citing works
Plasma miR-122 as a potential diagnostic and prognostic indicator in human glioma
Tang, Y. C., Zhao, S., Wang, J., Li, D., Ren, Q., & Tang, Y. (2017) · Neurological Sciences · doi:10.1007/s10072-017-2912-y · Cited by 31 · see citing works
Cochetti, G. G., Cari, L., Maulà, V., Cagnani, R., Paladini, A., Zingaro, M. D., Nocentini, G., & Mearini, E. E. (2022) · Cancers · doi:10.3390/cancers14051112 · Cited by 31 · see citing works
Gasmi, I., Machou, C., Rodrigues, A., Brouillet, A., Nguyen, T. C., Rousseau, B., Guillot, A., Rodriguez, C., Demontant, V., Ait-Ahmed, Y., et al. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.70408 · Cited by 31 · see citing works
MicroRNA-122 regulates caspase-8 and promotes the apoptosis of mouse cardiomyocytes
Zhang, Z. W., Li, H., Chen, S. S., Li, Y., Cui, Z., & Ma, J. (2017) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x20165760 · Cited by 30 · see citing works
Clinical Significance of Circulating miR-1273g-3p and miR-122-5p in Pancreatic Cancer
Mazza, T., Gioffreda, D., Fontana, A., Biagini, T., Carella, M., Palumbo, O., Maiello, E., Bazzocchi, F., Andriulli, A., & Tavano, F. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00044 · Cited by 29 · see citing works
Yin, L., Keeler, G. D., Zhang, Y., Hoffman, B. E., Ling, C., Qing, K., & Srivastava, A. (2020) · Gene Therapy · doi:10.1038/s41434-020-0140-1 · Cited by 29 · see citing works
CREB1, a direct target of miR-122, promotes cell proliferation and invasion in bladder cancer
Guo, L., Yin, M., & Wang, Y. (2018) · Oncology Letters · doi:10.3892/ol.2018.9118 · Cited by 29 · see citing works
Ultrasound-Assisted miR-122-Loaded Polymeric Nanodroplets for Hepatocellular Carcinoma Gene Therapy
Guo, H., Xu, M. T., Cao, Z., Li, W., Chen, L., Xie, X., Wang, W., & Liu, J. (2019) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.9b00983 · Cited by 29 · see citing works
Saleh, A. A., Soliman, S. E.-S., Habib, M. S. E., Gohar, S. F., & Abo-Zeid, G. S. (2019) · Molecular Biology Reports · doi:10.1007/s11033-019-04727-5 · Cited by 28 · see citing works
Qin, S., Ning, M., Liu, Q., Ding, X., Wang, Y., & Liu, Q. (2021) · Bioengineered · doi:10.1080/21655979.2021.1962685 · Cited by 28 · see citing works
miR-122-5p as a novel biomarker for alpha-fetoprotein-producing gastric cancer
Maruyama, S., Furuya, S., Shiraishi, K., Shimizu, H., Akaike, H., Hosomura, N., Kawaguchi, Y., Amemiya, H., Kawaida, H., Sudo, M., et al. (2018) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v10.i10.344 · Cited by 26 · see citing works
MiR-122 promotes renal cancer cell proliferation by targeting Sprouty2
Wang, Z., Qin, C., Zhang, J., Han, Z., Tao, J., Cao, Q., Zhou, W., Xu, Z., Zhao, C., Tan, R., et al. (2017) · Tumor Biology · doi:10.1177/1010428317691184 · Cited by 24 · see citing works
Shyu, Y., Lee, T., Lu, M., Chen, J.-R., Chien, R., Chen, H.-Y., Lin, J., Tsou, A., Chen, Y., Hsieh, C.-W., et al. (2016) · Journal of Translational Medicine · doi:10.1186/s12967-016-0956-z · Cited by 24 · see citing works
Babakhanzadeh, E., Khodadadian, A., Nazari, M., Tezerjani, M. D., Zarch, S. M. A., Ghasemifar, S., Hosseinnia, M., & Mazaheri, M. (2020) · International Journal of General Medicine · doi:10.2147/ijgm.s255431 · Cited by 24 · see citing works
Circ_0072995 Promotes Ovarian Cancer Progression Through Regulating miR-122-5p/SLC1A5 Axis
Huang, X., Luo, Y., & Li, X. (2021) · Biochemical Genetics · doi:10.1007/s10528-021-10092-5 · Cited by 23 · see citing works
Yang, J., Yuan, Y., Yang, X., Hong, Z., & Yang, L. (2017) · Pathology - Research and Practice · doi:10.1016/j.prp.2017.06.017 · Cited by 23 · see citing works
Li, A., Wu, J., Zhai, A., Qian, J., Wang, X., Qaria, M. A., Zhang, Q., Li, Y., Fang, Y., Kao, W., et al. (2019) · International Journal of Oncology · doi:10.3892/ijo.2019.4870 · Cited by 23 · see citing works
Lee, H. M., Wong, W. K. K., Fan, B., Lau, E. S. H., Hou, Y. J., Chun Kwan, O., Luk, A. O. Y., Chow, E., Ronald, C. W., Chan, J. C. N., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-03222-x · Cited by 22 · see citing works
MicroRNA‑122 regulates docetaxel resistance of prostate cancer cells by regulating PKM2
Zhu, Z., Tang, G., & Yan, J. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.9377 · Cited by 21 · see citing works
Yh, L., Jl, L., Wang, Z., Xh, Z., Xb, C., & Mq, W. (2019) · PubMed · doi:10.26355/eurrev_201901_16876 · Cited by 21 · see citing works
Zhu, H., Mi, Y., Jiang, X. L., Zhou, X., Li, R., Wei, Z., Jiang, H., Lu, J., & Sun, X. (2016) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-016-2121-8 · Cited by 20 · see citing works
Kw, L., Sh, W., Wei, X., Yz, H., & Li, Z.-H. (2020) · PubMed · doi:10.26355/eurrev_202012_24163 · Cited by 20 · see citing works
Hu, X., Zhang, L., Tian, J., & Ma, J. (2021) · World Journal of Surgical Oncology · doi:10.1186/s12957-021-02232-3 · Cited by 20 · see citing works
Yuan, Q., Yu, H., Chen, J., Song, X., & Sun, L. (2020) · Cancer Cell International · doi:10.1186/s12935-020-01174-2 · Cited by 19 · see citing works
Ma, W., Zhao, X., Xue, N., Gao, Y., & Xu, Q. (2021) · IUBMB Life · doi:10.1002/iub.2452 · Cited by 18 · see citing works
miR-122 Inhibits the Cervical Cancer Development by Targeting the Oncogene RAD21
Yang, Y., Liu, Y., Liu, W., Li, C., Liu, Y., Hu, W., & Song, H. (2021) · Biochemical Genetics · doi:10.1007/s10528-021-10098-z · Cited by 17 · see citing works
MiR-181b Expression Levels as Molecular Biomarker for Type 2 Diabetes
Zarch, S. M. A., Mehrjardi, M. Y. V., Babakhanzadeh, E., Nazari, M., Talebi, M., Zeniali, F., & Dehghani, M. (2019) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 16 · see citing works
Lowey, B., Hertz, L. M., Chiu, S., Valdez, K., Li, Q., & Liang, T. J. (2019) · mBio · doi:10.1128/mbio.01617-19 · Cited by 16 · see citing works
Akuta, N., Kawamura, Y., Suzuki, F., Saitoh, S., Arase, Y., Muraishi, N., Fujiyama, S., Sezaki, H., Hosaka, T., Kobayashi, M., et al. (2021) · Oncology · doi:10.1159/000519995 · Cited by 15 · see citing works
Liu, H., Hou, T., Ju, W., Xing, Y., Zhang, X., & Yang, J. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.9995 · Cited by 14 · see citing works
Wang, J., Yu, P., Yu, J., Luo, J., Sun, Z., Sun, F., Kong, Z., & Wang, J.-L. (2021) · PubMed Central · Cited by 14 · see citing works
Esophageal cancer-selective expression of TRAIL mediated by MREs of miR-143 and miR-122
Zhou, K., Yan, Y., & Zhao, S. (2014) · Tumor Biology · doi:10.1007/s13277-014-1768-5 · Cited by 13 · see citing works
Inhibition of apoptosis by miR‑122‑5p in α‑fetoprotein‑producing gastric cancer
Maruyama, S., Furuya, S., Shiraishi, K., Shimizu, H., Saito, R., Akaike, H., Hosomura, N., Kawaguchi, Y., Amemiya, H., Kawaida, H., et al. (2019) · Oncology Reports · doi:10.3892/or.2019.7023 · Cited by 12 · see citing works
LncRNA LINC00974 Downregulates miR-122 to Upregulate RhoA in Oral Squamous Cell Carcinoma
Tian, Y., Zhong, L., Gao, S.-L., Yu, Y., Sun, D., Liu, X., Ji, J., Yao, Y., Liu, Y., & Jiang, Z. (2019) · Cancer Biotherapy and Radiopharmaceuticals · doi:10.1089/cbr.2019.2907 · Cited by 12 · see citing works
miR‑122‑5p suppresses the oncogenesis of PTC by inhibiting DUSP4 expression
Hu, N., Tian, Y., Song, Y., & Zang, L. (2021) · Molecular Medicine Reports · doi:10.3892/mmr.2021.12007 · Cited by 12 · see citing works
[miR-122-5p inhibits the proliferation of melanoma cells by targeting NOP14].
Li, J., Zhao, R., Fang, R., & Wang, J. (2018) · Europe PMC (PubMed Central) · doi:10.12122/j.issn.1673-4254.2018.11.14 · Cited by 10 · see citing works
Zhan, G., Jiang, H., Yang, R., & Yang, K. (2021) · PubMed Central · Cited by 9 · see citing works
Beg, M. M. A., Guru, S. A., Abdullah, S. M., Ahmad, I. S., Rizvi, A., Akhter, J., Goyal, Y., & Verma, A. K. (2021) · Oncology Research and Treatment · doi:10.1159/000518722 · Cited by 8 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- [95]Shirvani H Ghanavi J Aliabadi A Mousavinasab F Talebi M Majidpour J MiR-211 play dual regulatory role in cancer development: from tumor suppressor to tumor enhancer Cell Signal 2022 101 110504 36309329
Cited by
Sorted by citations
RETRACTED: microRNA-382 as a tumor suppressor? Roles in tumorigenesis and clinical significance
Fattahi, M., Shahrabi, S., Saadatpour, F., Rezaee, D., Beyglu, Z., Delavari, S., Amrolahi, A., Ahmadi, S., Bagheri‐Mohammadi, S., Noori, E., et al. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125863 · Cited by 75 · see citing works
Self-citationRetractedRezaee, D., Saadatpour, F., Akbari, N., Zoghi, A., Najafi, S., Beyranvand, P., Rarani, F. Z., Rashidi, M. A., Bagheri‐Mohammadi, S., & Bakhtiari, M. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102090 · Cited by 74 · see citing works
Self-citationAn interplay between non-coding RNAs and gut microbiota in human health
Fardi, F., Khasraghi, L. B., Shahbakhti, N., Naseriyan, A. S., Najafi, S., Sanaaee, S., Alipourfard, I., Zamany, M., Karamipour, S., Jahani, M., et al. (2023) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2023.110739 · Cited by 58 · see citing works
Self-citationNon-coding RNAs/DNMT3B axis in human cancers: from pathogenesis to clinical significance
Huang, C., Azizi, P., Vazirzadeh, M., Zarch, S. M. A., Aghaei-Zarch, F., Ghanavi, J., & Farnia, P. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04510-y · Cited by 56 · see citing works
Self-citationZaki, M. B., Abulsoud, A. I., Elshaer, S. S., Fathi, D., Abdelmaksoud, N. M., El‐Mahdy, H. A., Ismail, A., Elsakka, E. G. E., Sallam, A.-A. M., & Doghish, A. S. (2023) · Pathology - Research and Practice · doi:10.1016/j.prp.2023.154437 · Cited by 53 · see citing works
The role of microRNA-185 in the pathogenesis of human diseases: A focus on cancer
Pordel, S., Khorrami, M., Saadatpour, F., Rezaee, D., Cho, W. C. S., Jahani, S., Zarch, S. M. A., Hashemi, E., & Najafi, S. (2023) · Pathology - Research and Practice · doi:10.1016/j.prp.2023.154729 · Cited by 47 · see citing works
Self-citationmicroRNA-184 in the landscape of human malignancies: a review to roles and clinical significance
Fattahi, M., Rezaee, D., Fakhari, F., Najafi, S., Zarch, S. M. A., Beyranvand, P., Rashidi, M. A., Bagheri‐Mohammadi, S., Rarani, F. Z., Bakhtiari, M., et al. (2023) · Cell Death Discovery · doi:10.1038/s41420-023-01718-1 · Cited by 46 · see citing works
Self-citationRole of Circulating microRNAs in Liver Disease and HCC: Focus on miR-122
Colaianni, F., Zelli, V., Compagnoni, C., Miscione, M. S., Rossi, M., Vecchiotti, D., Padova, M. D., Alesse, E., Zazzeroni, F., & Tessitore, A. (2024) · Genes · doi:10.3390/genes15101313 · Cited by 46 · see citing works
Exosome-based miRNA delivery: Transforming cancer treatment with mesenchymal stem cells
Balaraman, A. K., Babu, M. A., Afzal, M., Sanghvi, G. V., Rekha, M. M., Gupta, S., Rana, M., Ali, H., Goyal, K., Subramaniyan, V., et al. (2025) · Regenerative Therapy · doi:10.1016/j.reth.2025.01.019 · Cited by 43 · see citing works
Zarch, S. M. A., Nia, A. H. S., Nouri, M., Mousavinasab, F., Najafi, S., Bagheri‐Mohammadi, S., Aghaei-Zarch, F., Toolabi, A., Rasoulzadeh, H., Ghanavi, J., et al. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115054 · Cited by 41 · see citing works
Self-citationMicrobiome modulation in inflammatory diseases: Progress to microbiome genetic engineering
Mousavinasab, F., karimi, R., Taheri, S., Ahmadvand, F., Sanaaee, S., Najafi, S., Halvaii, M. S., Haghgoo, A., Zamany, M., Majidpoor, J., et al. (2023) · Cancer Cell International · doi:10.1186/s12935-023-03095-2 · Cited by 34 · see citing works
Self-citationZhang, H., Dong, X., Ding, X., Liu, G., Yang, F., Song, Q., Sun, H., Chen, G., Li, S., Li, Y., et al. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04613-6 · Cited by 31 · see citing works
Circulating microRNAs for Early Diagnosis of Ovarian Cancer: A Systematic Review and Meta-Analysis
Frisk, N. L. S., Sørensen, A. E., Pedersen, O. B., & Dalgaard, L. T. (2023) · Biomolecules · doi:10.3390/biom13050871 · Cited by 27 · see citing works
The emerging role of miRNA-122 in infectious diseases: Mechanisms and potential biomarkers
Mirzaei, R., Karampoor, S., & Korotkova, N. L. (2023) · Pathology - Research and Practice · doi:10.1016/j.prp.2023.154725 · Cited by 25 · see citing works
Shahpar, M. G., Pakravan, K., Razmara, E., Amooie, F., Mahmoudian, M., Heshmati, M., & Babashah, S. (2024) · BMC Cancer · doi:10.1186/s12885-024-12190-0 · Cited by 27 · see citing works
Non-coding RNAs: A new frontier in benzene-mediated toxicity
Nia, A. H. S., Ardabili, M. R., Sheikhvand, M., Bagheri‐Mohammadi, S., Niknejad, H., Rasoulzadeh, H., Movafagh, A., Neghad, S. K., Baniasadi, M., Ashrafi‐Asgarabad, A., et al. (2023) · Toxicology · doi:10.1016/j.tox.2023.153660 · Cited by 21 · see citing works
Xia, B., Liu, Y., Wang, J., Lu, Q., Lv, X., Deng, K., & Yang, J. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106880 · Cited by 21 · see citing works
Decoding Cancer through Silencing the Mitochondrial Gatekeeper VDAC1
Arif, T., Shteinfer‐Kuzmine, A., & Shoshan‐Barmatz, V. (2024) · Biomolecules · doi:10.3390/biom14101304 · Cited by 21 · see citing works
A modular mRNA platform for programmable induction of tumour-specific immunogenic cell death
Dong, S., Tsai, S. N., Xu, Y., Gong, F., Young, T. L., Solek, N. C., Chen, D. X. W., Healy, L., Savguira, M., Zhou, M., et al. (2025) · Nature Nanotechnology · doi:10.1038/s41565-025-02045-5 · Cited by 20 · see citing works
Tan, C. Y., Ong, H. F., Lim, C. H., Tan, M. S., Ooi, E. H., & Wong, K. (2025) · BMC Bioinformatics · doi:10.1186/s12859-025-06111-6 · Cited by 19 · see citing works
X-ray cross-complementing family: the bridge linking DNA damage repair and cancer
Liu, Q., Qiu, P., Zhang, B., & Tan, Y. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04447-2 · Cited by 19 · see citing works
Yang, Y., Wang, Z., Li, X., Lv, J., Zhong, R., Gao, S., Zhang, F., & Chen, W. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04604-7 · Cited by 19 · see citing works
Han, L., Jiang, Y., Shi, M., Gan, L., Wu, Z., Xue, M., Zhu, Y., Xiong, C., Wang, T., Lin, X., et al. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04702-6 · Cited by 19 · see citing works
Goyal, A., Afzal, M., Goyal, K., Ganesan, S., Kumari, M., Sunitha, S., Dash, A., Saini, S., Rana, M., Gupta, G., et al. (2025) · Regenerative Therapy · doi:10.1016/j.reth.2025.03.006 · Cited by 17 · see citing works
Chen, M., Xu, K., He, Y., Jin, J., Mao, R., Gao, L., Zhang, Y., Wang, G., Gao, P., Xie, M., et al. (2023) · International Journal of COPD · doi:10.2147/copd.s400999 · Cited by 17 · see citing works
Hoorzad, P., Mousavinasab, F., Tofigh, P., Kalahroud, E. M., Zarch, S. M. A., Salehi, A., Fattahi, M., & Le, B. N. (2023) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2023.110804 · Cited by 16 · see citing works
Role of Circulating Exosomal miRNA-3976 in Early Diabetic Retinopathy.
Yang, S., Zhang, J., Zeng, T., Zheng, J., Min, J., & Chen, L. (2023) · PubMed Central · doi:10.2147/ijn.s414393 · Cited by 15 · see citing works
Ageeli, E. A. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46110711 · Cited by 16 · see citing works
van der Merwe, M., Myburgh, K. H., Garnis, C., Towle, R. M., & Engelbrecht, A. (2025) · Gene · doi:10.1016/j.gene.2025.149467 · Cited by 13 · see citing works
LRRC8A as a central mediator promotes colon cancer metastasis by regulating PIP5K1B/PIP2 pathway
Zhang, H., Liu, R., Jing, Z., Li, C., Fan, W., Li, H., Li, H., Ren, J., Cui, S., Zhao, W., et al. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2024.167066 · Cited by 13 · see citing works
Ishwarya, R., Rajaganesh, R., Mani, G., Kalaiarasi, G., Narayanasamy, A., Tharani, J., Kavithaa, K., & Sangeetha, D. (2024) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2024.103417 · Cited by 13 · see citing works
Exosome biosensors for detection of liver cancer
Vafadar, A., Younesi, M., Babadi, S., Alizadeh, M., Movahedpour, A., & Savardashtaki, A. (2025) · Clinica Chimica Acta · doi:10.1016/j.cca.2025.120199 · Cited by 13 · see citing works
Ciofoaia, V., Chen, W., Bakain, T. W., Gay, M. D., Shivapurkar, N., & Smith, J. P. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16050611 · Cited by 12 · see citing works
Mitchell, M. I., Khalil, M., Ben‐Dov, I. Z., Alvarez‐Perez, J. R., Illsley, N. P., Zamudio, S., Al‐Khan, A., & Loudig, O. D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105102 · Cited by 9 · see citing works
Neuronal Enriched Extracellular Vesicle miR-122-5p as a Potential Biomarker for Alzheimer’s Disease
Subasinghe, K., Hall, C. L., Rowe, M., Zhou, Z., Barber, R. C., & Phillips, N. (2025) · Cells · doi:10.3390/cells14221784 · Cited by 9 · see citing works
Żyła, J., Dziadziuszko, R., Marczyk, M., Sitkiewicz, M., Szczepanowska, M., Bottoni, E., Veronesi, G., Rzyman, W., Polańska, J., & Widlak, P. (2023) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2023.09.010 · Cited by 9 · see citing works
Lei, J., Pan, Y., Gao, R., He, B., Wang, Z., Lei, X., Zhang, Z., Yang, N., & Yan, M. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04396-w · Cited by 8 · see citing works
Sarkar, S., Bishoyi, A. K., Roopashree, R., Thakur, V., Kaur, M., Pal, P., Alqahtani, T., Al-Qahtani, A. S., Uti, D. E., & Alum, E. U. (2025) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70723 · Cited by 8 · see citing works
A 2D/3D nanoplatform for electrochemical diagnosis of miRNA-122 in breast cancer cell lines
Esmaeilian, A., Arab, N., Yazdian, F. A., Hosseini, M., Mortazavi, S. M. R., & Ganjali, M. R. (2025) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2025.109209 · Cited by 8 · see citing works
Wu, H., Fu, Q., Li, Z., Wei, H., & Qin, S. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e18238 · Cited by 7 · see citing works
The role of lncRNAs in the interplay of signaling pathways and epigenetic mechanisms in glioma
Yildiz, C. B., Du, J., Mohan, K. N., Zimmer‐Bensch, G., & Abdolahi, S. (2025) · Epigenomics · doi:10.1080/17501911.2024.2442297 · Cited by 7 · see citing works
Extracellular Vesicle miR-122-5p as a Prognostic Biomarker in Pediatric Classical Hodgkin Lymphoma
Salzmann, R. J. S., Garbin, A., Gaffo, E., Elia, C., Martire, G., Bortoluzzi, S., Tondo, A., Muggeo, P., Sala, A., Pizzi, M., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252413243 · Cited by 7 · see citing works
Bamahel, A. S., Sun, X., Wu, W., Mu, C., Liu, J., Bi, S., & Xu, H. (2025) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-025-01686-6 · Cited by 7 · see citing works
Fath, M. K., Nezami, P. V., Keleshtery, Z. A., Azgomi, Z. S., Chegini, S. N., Shahriarinour, M., Saraabestan, S. S., Diyarkojouri, M., Nikpassand, M., & Ranji, N. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.4609 · Cited by 7 · see citing works
Qian, L., Zhang, Y., Wang, G., Li, B., Zhou, H., Qiu, J., & Qin, L. (2023) · Biochemical Genetics · doi:10.1007/s10528-023-10521-7 · Cited by 7 · see citing works
Song, B., Hou, G., Xu, M., & Chen, M. (2024) · Cellular Signalling · doi:10.1016/j.cellsig.2024.111101 · Cited by 7 · see citing works
Abbasifarid, A., Dorostkar, R., & Ghalavand, M. (2025) · Heliyon · doi:10.1016/j.heliyon.2025.e42961 · Cited by 6 · see citing works
Al-Juboori, S. K. E., & Al-Juboori, S. I. K. (2023) · Baghdad Science Journal · doi:10.21123/bsj.2023.9065 · Cited by 6 · see citing works
Hetta, . F., Hamed, H. M., Mekky, M. A., Abdelmalek, M. O., & Hassan, W. A. (2024) · Egyptian Liver Journal · doi:10.1186/s43066-024-00385-w · Cited by 5 · see citing works
Zhang, Z., Wang, M., Gao, X., Tai, G., Li, F., & Wang, Z. (2025) · Cellular Signalling · doi:10.1016/j.cellsig.2025.112039 · Cited by 5 · see citing works
Patel, N., Lawarde, A., Surisetti, S. M., Thiruselvam, P., Lingasamy, P., Sundararajan, V., Sajitha Lulu, S., Salumets, A., & Modhukur, V. (2025) · RNA Biology · doi:10.1080/15476286.2025.2577433 · Cited by 5 · see citing works
CircAGFG1 Promotes Ovarian Cancer Progression Through the miR-409-3 p/ZEB1 Axis
Luo, J., Zhong, H., Guo, M., Xiao, P., Cao, R., Zhao, M., & Jing, Y. (2024) · Technology in Cancer Research & Treatment · doi:10.1177/15330338241252423 · Cited by 5 · see citing works
Choudhary, A., Kumar, A., & Munshi, A. (2025) · Medical Oncology · doi:10.1007/s12032-025-02873-4 · Cited by 5 · see citing works
Li, Y., Du, X., Kong, X., Fang, Y., He, Z., Liu, D., Wu, H., Ji, J., Yang, X., Ye, L., et al. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.115952 · Cited by 5 · see citing works
The Efficacy of Electrochemotherapy with Dacarbazine on Melanoma Cells
Coşkun, A., Kayhan, H., Şentürk, F., Eşmekaya, M. A., & Canseven, A. G. (2024) · Bioelectricity · doi:10.1089/bioe.2023.0041 · Cited by 5 · see citing works
MicroRNAs at the crossroad of cancer therapeutics: insights from WNT signaling & flavonoids
Gupta, A., Mehrotra, A., Sood, A., Sharma, B., Yadav, V., Kaur, G., Sak, K., Satapathy, S. R., & Tuli, H. S. (2025) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2025.1616221 · Cited by 4 · see citing works
Jalili, M., & Jalilian, F. A. (2026) · Microbial Pathogenesis · doi:10.1016/j.micpath.2026.108346 · Cited by 4 · see citing works
Zhang, C., Zhu, F., Chen, Y., He, L. M., Zhang, T., Zhou, B., Ge, C., Wang, J., & Wu, B. (2024) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2024.135372 · Cited by 4 · see citing works
A novel serum m7G-harboring microRNA signature for cancer detection
Chen, Y., Xie, Y., Bi, L., Ci, H., Li, W., & Liu, D. (2024) · Frontiers in Genetics · doi:10.3389/fgene.2024.1270302 · Cited by 4 · see citing works
Dysregulation of miR-122, miR-574 and miR-375 in Egyptian patients with breast cancer
Elghoroury, E. A., Abdelghaffar, E. E., Kamel, S. A., Awadallah, E. A., Shalaby, A. M., El-Saeed, G. S. M., Mahmoud, E., Kamel, M. M., Abobakr, A., & Yousef, R. N. (2024) · PLoS ONE · doi:10.1371/journal.pone.0298536 · Cited by 4 · see citing works
Rahdar, A., Shabestari, S. M., Najafi, M., Shirzad, M., & Pandey, S. (2026) · Computational Biology and Chemistry · doi:10.1016/j.compbiolchem.2026.109025 · Cited by 3 · see citing works
Bhagat, S., Rakshith, H. S., Bhokare, K., Datta, N., Vastrad, N., David, M., Maharaj, N. R., & Anand, K. (2025) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c00119 · Cited by 3 · see citing works
Boonto, T., Phetkong, C., & Ariyachet, C. (2025) · Journal of Biomedical Research · doi:10.7555/jbr.39.20250056 · Cited by 3 · see citing works
Functional Roles of the lncRNA MALAT1 in Glioma
Moftakhar, A., Najafi, S., Anbiyaee, O., Farzaneh, M., & Khoshnam, S. E. (2023) · Current Cancer Therapy Reviews · doi:10.2174/1573394719666230720164009 · Cited by 3 · see citing works
Self-citationLui, K., Huang, Y. K., Sheikh, M. S., Cheung, K., Tam, W. Y., Sun, K.-T., Cheng, K. M., Ng, W. W. M., & Loh, A. W.-K. (2023) · Journal of Cancer · doi:10.7150/jca.84267 · Cited by 3 · see citing works
Kadry, M. O. (2024) · Toxicology Reports · doi:10.1016/j.toxrep.2024.03.005 · Cited by 3 · see citing works
Tenhaken, V., Seternes, O. M., Cascorbi, I., & Bruckmueller, H. (2025) · BMC Cancer · doi:10.1186/s12885-025-14434-z · Cited by 3 · see citing works
Nourian, R., Motamedi, S. A., & Pourfard, M. (2024) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2024.109348 · Cited by 2 · see citing works
Saftawy, E. A. E., Aboulhoda, B. E., Elkhalek, M. A. A., Alghamdi, M. A., & AlHariry, N. S. (2025) · Pathology - Research and Practice · doi:10.1016/j.prp.2025.155815 · Cited by 2 · see citing works
Jabbari, N., & Sabokrouh, A. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-03836-2 · Cited by 2 · see citing works
Kadry, M. O., & Megeed, R. M. A. (2025) · Cancer Nanotechnology · doi:10.1186/s12645-025-00331-4 · Cited by 2 · see citing works
Chanda, M., Mekasuwandumrong, C., Wilasrusmee, K. T., Panich, U., & Jirawatnotai, S. (2025) · Hepatoma Research · doi:10.20517/2394-5079.2025.15 · Cited by 2 · see citing works
A Unified Framework for Model-Informed and Agentic RNA DesignPreprint
Riley, A. T., Vlasity, M., Becicka, W. M., Huang, J., Pang, S., Wong, W. W., Grinstaff, M. W., & Green, A. A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.17.659751 · Cited by 3 · see citing works
Extrahepatic and Circulating miR-122: Diagnostic Implications and Future Directions
Royfman, R., McTague, J. R., Ranabothu, M., & Menon, B. (2025) · MicroRNA · doi:10.2174/0122115366334187250116164121 · Cited by 1 · see citing works
Kit, O. I., Frantsiyants, E. M., Kaplieva, I. V., Kutilin, D. S., Neskubina, I. V., Bandovkina, V. A., Trepitaki, L. K., & Surikova, E. I. (2025) · Advances in molecular oncology · doi:10.17650/2313-805x-2025-12-1-76-83 · Cited by 1 · see citing works
Wang, S., Shi, S., Wu, D., Li, K., Yang, G., Qi, R., Xu, L., Feng, N., Zhong, V. W., & Du, X. (2025) · Food & Function · doi:10.1039/d5fo02781k · Cited by 1 · see citing works
Flores‐Fortis, M., Perez‐Añorve, I. X., Patiño-Morales, C. C., Soto‐Reyes, E., la Rosa, C. H. G.-D., Manzo-Merino, J., Aguilar‐Rojas, A., Villegas‐Sepúlveda, N., & Aréchaga-Ocampo, E. (2025) · Clinical & Translational Oncology · doi:10.1007/s12094-025-04082-x · Cited by 1 · see citing works
Hassan, M., Malik, A., Shahzadi, S., & Kloczkowski, A. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47110948 · Cited by 1 · see citing works
Osman, E. A., Eltaweel, N. H., Madbouly, M., Mosbah, O., Gaber, M. G., & Khanany, F. M. (2025) · BMC Nephrology · doi:10.1186/s12882-025-04619-w · Cited by 1 · see citing works
Smith, J. P., Nkulikiyimana, G. C., Cao, H., Chen, W., Kallakury, B., Kwagyan, J., Duttargi, A., & Weinberg, B. A. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18030379 · Cited by 1 · see citing works
Thakur, S., Munshi, A., & Kaur, P. (2026) · Molecular Biotechnology · doi:10.1007/s12033-026-01576-z · Cited by 1 · see citing works
Topology and Dynamics of Transcriptome (Dys)Regulation
Planat, M. R. P., & Chester, D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25094971 · Cited by 1 · see citing works
microRNA-122 gene expression in Iraqi patients with hepatocellular carcinoma
Mohsen, R. T., Al-Taee Haneen, Z., Habeeb, W. H., Abd-Alazeez, R. A., Hassan, S., & Mohsen, S. A. A. E. (2024) · Asia-Pacific Journal of Molecular Biology and Biotechnology · doi:10.35118/apjmbb.2024.032.4.25 · Cited by 1 · see citing works
Han, J. W., Yang, J. Y., Kim, Y., An, S., Yoo, E., Park, I. H., Lee, S.-W., Lee, H.-J., Lee, T. G., Jung, W. H., et al. (2026) · Molecular Therapy: Nucleic Acids · doi:10.1016/j.omtn.2026.103101 · Cited by 1 · see citing works
Zhang, H., Dong, X., Ding, X., Liu, G., Yang, F., Song, Q., Sun, H., Chen, G., Li, S., Li, Y., et al. (2023) · Figshare · doi:10.6084/m9.figshare.24792277
Sabokrouh, A., Ghaffari, N., Tafreshi, Z. K., Atabi, F., Sharifi, Z., & Mostavafi, S. K. S. (2025) · Avicenna Journal of Medical Biotechnology · doi:10.18502/ajmb.v17i1.17674
Li, N., Liu, J., Zheng, T., Li, D., Zhang, L., Zhang, S., Xia, Q., Stoika, R. S., Liu, K., & Zhang, Y. (2025) · Journal of Applied Toxicology · doi:10.1002/jat.4830
Yaman, S. Ö., Petrović, N., Yaman, S., Akıdan, O., Cimbek, A., Bayçelebi, G., Srdić‐Rajić, T., Sami, A. S., & Mısır, S. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262311401
Han, L., Jiang, Y., Shi, M., Gan, L., Wu, Z., Xue, M., Zhu, Y., Xiong, C., Wang, T., Lin, X., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26643412
Lei, J., Pan, Y., Gao, R., He, B., Wang, Z., Lei, X., Zhang, Z., Yang, N., & Yan, M. (2023) · Figshare · doi:10.6084/m9.figshare.23983350
Han, L., Jiang, Y., Shi, M., Gan, L., Wu, Z., Xue, M., Zhu, Y., Xiong, C., Wang, T., Lin, X., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26643397
Yang, Y., Wang, Z., Li, X., Lv, J., Zhong, R., Gao, S., Zhang, F., & Chen, W. (2024) · Figshare · doi:10.6084/m9.figshare.26641582
Han, L., Jiang, Y., Shi, M., Gan, L., Wu, Z., Xue, M., Zhu, Y., Xiong, C., Wang, T., Lin, X., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26643403
Han, L., Jiang, Y., Shi, M., Gan, L., Wu, Z., Xue, M., Zhu, Y., Xiong, C., Wang, T., Lin, X., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26643391
Han, L., Jiang, Y., Shi, M., Gan, L., Wu, Z., Xue, M., Zhu, Y., Xiong, C., Wang, T., Lin, X., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26643394
Han, L., Jiang, Y., Shi, M., Gan, L., Wu, Z., Xue, M., Zhu, Y., Xiong, C., Wang, T., Lin, X., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26643406
Lei, J., Pan, Y., Gao, R., He, B., Wang, Z., Lei, X., Zhang, Z., Yang, N., & Yan, M. (2023) · Figshare · doi:10.6084/m9.figshare.23983353
Shahpar, M. G., Pakravan, K., Razmara, E., Amooie, F., Mahmoudian, M., Heshmati, M., & Babashah, S. (2024) · Figshare · doi:10.6084/m9.figshare.25522689
Han, L., Jiang, Y., Shi, M., Gan, L., Wu, Z., Xue, M., Zhu, Y., Xiong, C., Wang, T., Lin, X., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26643400
Han, L., Jiang, Y., Shi, M., Gan, L., Wu, Z., Xue, M., Zhu, Y., Xiong, C., Wang, T., Lin, X., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26643409
- Authors
- Faramin Lashkarian, M., Hashemipour, N., Niaraki, N., Soghala, S., Moradi, A., Sarhangi, S., Hatami, M., Aghaei-Zarch, F., Khosravifar, M., Mohammadzadeh, A., Najafi, S., Majidpoor, J., Farnia, P., & Aghaei-Zarch, S. M.
- Affiliations
- Yazd University (IR)
- Shahid Beheshti University (IR)
- Islamic Azad University, Tehran (IR)
- Kerman University of Medical Sciences (IR)
- University of Pennsylvania (US)
- Gonabad University of Medical Sciences (IR)
- Masih Daneshvari Hospital (IR)
- Corresponding author
- Aghaei-Zarch, Fatemehsadat
- Najafi, Sajad
- Majidpoor, Jamal
- Farnia, Poopak
- ORCID
- Venue
- Cancer Cell International
- Published
- 2023-02-20
- Volume
- 23
- Issue
- 1
- Pages
- 29-29
- ISSN
- 1475-2867 (ISSN-L)
- PMC
- PMC9940444
- OpenAlex
- W4321371253
- Cited by
- 105
- References
- 121
- Citations by year
- 2026: 9 · 2025: 36 · 2024: 30 · 2023: 30
- FWCI
- 3.35
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Cancer Cell International (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer-related molecular mechanisms research
- Health Sciences › Medicine › Oncology › Cancer-related Molecular Pathways
- Keywords
- miR-122, microRNA, cancer, post-transcriptional regulation, microRNA dysregulation, diagnostic biomarkers, prognostic factors, cancer therapy response, miR-21, miR-210, miR-223, miR-424, miR-206
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
