The DOI matches its Crossref record; 113 of the 113 references it cites were found in a registry or an index.
The emerging role of microRNAs and long noncoding RNAs in drug resistance of hepatocellular carcinoma
Open accessAbstract
Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and the second most lethal human cancer. A portion of patients with advanced HCC can significantly benefit from treatments with sorafenib, adriamycin, 5-fluorouracil and platinum drugs. However, most HCC patients eventually develop drug resistance, resulting in a poor prognosis. The mechanisms involved in HCC drug resistance are complex and inconclusive. Human transcripts without protein-coding potential are known as noncoding RNAs (ncRNAs), including microRNAs (miRNAs), small nucleolar RNAs (snoRNAs), long noncoding RNAs (lncRNAs) and circular RNA (circRNA). Accumulated evidences demonstrate that several deregulated miRNAs and lncRNAs are important regulators in the development of HCC drug resistance which elucidates their potential clinical implications. In this review, we summarized the detailed mechanisms by which miRNAs and lncRNAs affect HCC drug resistance. Multiple tumor-specific miRNAs and lncRNAs may serve as novel therapeutic targets and prognostic biomarkers for HCC.
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Cites
6 retracted
Huang, H., Chen, J., Ding, C., Jin, X., Jia, Z., & Peng, J. (2018) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13605 · Cited by 150
RetractedLiu, K., Liu, S., Zhang, W., Jia, B., Tan, L., Jin, Z. X., & Liu, Y. (2015) · Oncology Reports · doi:10.3892/or.2015.4030 · Cited by 114
RetractedShi, L., Hong, X., Ba, L., He, X., Xiong, Y., Ding, Q., Yang, S., & Peng, G. (2019) · Cell Death and Disease · doi:10.1038/s41419-019-1332-8 · Cited by 69
RetractedmiR-222 regulates sorafenib resistance and enhance tumorigenicity in hepatocellular carcinoma
Liu, K., Liu, S., Zhang, W., Ji, B., Wang, Y., & Liu, Y. (2014) · International Journal of Oncology · doi:10.3892/ijo.2014.2577 · Cited by 51
RetractedLiu, K., Liu, S., Zhang, W., Ji, B., Wang, Y., & Liu, Y. (2021) · International Journal of Oncology · doi:10.3892/ijo.2021.5280 · Cited by 34
RetractedQue, K., Zhou, Y., You, Y., et al. (2018) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-018-0930-0 · Cited by 27
Retracted5-Fluorouracil: mechanisms of action and clinical strategies
Longley, D. B., Harkin, D. P., & Johnston, P. G. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1074 · Cited by 5,332
Wilhelm, S. M., Carter, C., Tang, L., Wilkie, D., McNabola, A., Rong, H., Chen, C., Zhang, X., Vincent, P., McHugh, M., et al. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-1443 · Cited by 4,017
El-Serag, H. B. (2011) · New England Journal of Medicine · doi:10.1056/nejmra1001683 · Cited by 3,529
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
Cech, T. R., & Steitz, J. A. (2014) · Cell · doi:10.1016/j.cell.2014.03.008 · Cited by 2,524
Cited by
Ghafouri-Fard, S., Abak, A., Tondro Anamag, F., Shoorei, H., Fattahi, F., Javadinia, S. A., Basiri, A., & Taheri, M. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.658636 · Cited by 193
Metadata
- Authors
- Wei, L., Wang, X., Lv, L., Liu, J., Xing, H., Song, Y., Xie, M., Lei, T., Zhang, N., & Yang, M.
- Venue
- Molecular Cancer
- Published
- 2019-10-25
- Volume
- 18
- Issue
- 1
- Pages
- 147-147
- ISSN
- 1476-4598 (ISSN-L)
- OpenAlex
- W2982161529
- Cited by
- 339
- References
- 113
- FWCI
- 15.55
- Type
- journal article
- Language
- en
- Open access
- gold
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- Wei, L., Wang, X., Lv, L., Liu, J., Xing, H., Song, Y., Xie, M., Lei, T., Zhang, N., & Yang, M. (2019). The emerging role of microRNAs and long noncoding RNAs in drug resistance of hepatocellular carcinoma. Molecular Cancer. https://doi.org/10.1186/s12943-019-1086-z
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
