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The DOI matches its Crossref record; 159 of the 159 references it cites were found in a registry or an index.

The potential role of RNA N6-methyladenosine in Cancer progression

Open access
Wang, Tianyi, Kong, Shan, Tao, Mei, Ju, Shaoqing·2020·Molecular Cancer

Abstract

N6-methyladenosine (m6A) is considered the most common, abundant, and conserved internal transcript modification, especially in eukaryotic messenger RNA (mRNA). m6A is installed by m6A methyltransferases (METTL3/14, WTAP, RBM15/15B, VIRMA and ZC3H13, termed “writers”), removed by demethylases (FTO, ALKBH5, and ALKBH3, termed “erasers”), and recognized by m6A-binding proteins (YTHDC1/2, YTHDF1/2/3, IGF2BP1/2/3, HNRNP, and eIF3, termed “readers”). Accumulating evidence suggests that m6A RNA methylation greatly impacts RNA metabolism and is involved in the pathogenesis of many kinds of diseases, including cancers. In this review, we focus on the physiological functions of m6A modification and its related regulators, as well as on the potential biological roles of these elements in human tumors.

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Metadata

Authors
Wang, T., Kong, S., Tao, M., & Ju, S.
Venue
Molecular Cancer
Published
2020-05-12
Volume
19
Issue
1
Pages
88-88
ISSN
1476-4598 (ISSN-L)
OpenAlex
W3028187297
Cited by
1,013
References
159
FWCI
38.72
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: The potential role of RNA N6-methyladenosine in Cancer progression. https://app.cochat.ai/papers/10.1186/s12943-020-01204-7
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Wang, T., Kong, S., Tao, M., & Ju, S. (2020). The potential role of RNA N6-methyladenosine in Cancer progression. Molecular Cancer. https://doi.org/10.1186/s12943-020-01204-7

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