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Cited by 275Physical Activity and HealthErgonomics and Musculoskeletal DisordersContext-Aware Activity Recognition Systems

The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.

New global guidelines on sedentary behaviour and health for adults: broadening the behavioural targets

Open access
Dempsey, Paddy C., Biddle, Stuart J. H., Buman, Matthew P., Chastin, Sebastien, Ekelund, Ulf, Friedenreich, Christine M., Katzmarzyk, Peter T., Leitzmann, Michael F., Stamatakis, Emmanuel, van der Ploeg, Hidde P., Willumsen, Juana, Bull, Fiona·2020·International Journal of Behavioral Nutrition and Physical Activity
DOI 10.1186/s12966-020-01044-0PMC PMC7691115
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Abstract

Background: In 2018, the World Health Organisation (WHO) commenced a program of work to update the 2010 Global Recommendations on Physical Activity for Health, for the first-time providing population-based guidelines on sedentary behaviour. This paper briefly summarizes and highlights the scientific evidence behind the new sedentary behaviour guidelines for all adults and discusses its strengths and limitations, including evidence gaps/research needs and potential implications for public health practice. Methods: An overview of the scope and methods used to update the evidence is provided, along with quality assessment and grading methods for the eligible new systematic reviews. The literature search update was conducted for WHO by an external team and reviewers used the AMSTAR 2 (Assessment of Multiple Systematic Reviews) tool for critical appraisal of the systematic reviews under consideration for inclusion. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) method was used to rate the certainty (i.e. very low to high) of the evidence. Results: The updated systematic review identified 22 new reviews published from 2017 up to August 2019, 14 of which were incorporated into the final evidence profiles. Overall, there was moderate certainty evidence that higher amounts of sedentary behaviour increase the risk for all-cause, cardiovascular disease (CVD) and cancer mortality, as well as incidence of CVD, cancer, and type 2 diabetes. However, evidence was deemed insufficient at present to set quantified (time-based) recommendations for sedentary time. Moderate certainty evidence also showed that associations between sedentary behaviour and all-cause, CVD and cancer mortality vary by level of moderate-to-vigorous physical activity (MVPA), which underpinned additional guidance around MVPA in the context of high sedentary time. Finally, there was insufficient or low-certainty systematic review evidence on the type or domain of sedentary behaviour, or the frequency and/or duration of bouts or breaks in sedentary behaviour, to make specific recommendations for the health outcomes examined. Conclusions: The WHO 2020 guidelines are based on the latest evidence on sedentary behaviour and health, along with interactions between sedentary behaviour and MVPA, and support implementing public health programmes and policies aimed at increasing MVPA and limiting sedentary behaviour. Important evidence gaps and research opportunities are identified.

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Fig. 1 Joint associations of sedentary (sitting) time and MVPA with risk of all-cause mortality based on data by Ekelund et al. [4] – now also broadly applicable for risk of CVD and cancer mortality [3]. Orange and yellow shading represents transitional decreases in risk. For context, data analysis ranges for all-cause mortality [4] were based on four levels of self-reported sedentary time (< 4, 4–6, 6–8, > 8 h/day) and MVPA (∼5, 25–35, 50–65, 60–75 min/day), but specific scales are intentionally left blank and could vary considerably for either device-based measures (e.g. hip or thigh accelerometry), by different health outcomes (e.g. type 2 diabetes, adiposity), or by different sub-populations (e.g. frail/elderly adults, people living with some chronic conditions or disabilities). Heat map adapted from the PAGAC [9] report
Fig. 1 Joint associations of sedentary (sitting) time and MVPA with risk of all-cause mortality based on data by Ekelund et al. [4] – now also broadly applicable for risk of CVD and cancer mortality [3]. Orange and yellow shading represents transitional decreases in risk. For context, data analysis ranges for all-cause mortality [4] were based on four levels of self-reported sedentary time (< 4, 4–6, 6–8, > 8 h/day) and MVPA (∼5, 25–35, 50–65, 60–75 min/day), but specific scales are intentionally left blank and could vary considerably for either device-based measures (e.g. hip or thigh accelerometry), by different health outcomes (e.g. type 2 diabetes, adiposity), or by different sub-populations (e.g. frail/elderly adults, people living with some chronic conditions or disabilities). Heat map adapted from the PAGAC [9] reportCC BY · PubMed Central

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Show all 54 references

Research works printed but not linked: 5

  1. Rütten A, Pfeifer K. National recommendations for physical activity and physical activity promotion. Erlangen: FAU University Press; 2016.
  2. Bull F, Willumsen J. World Health Organization. Guidelines on physical activity and sedentary behaviour. Geneva: World Health Organization; 2020.
  3. Wang J, Huang L, Gao Y, Wang Y, Chen S, Huang J, et al. Physically active individuals have a 23% lower risk of any colorectal neoplasia and a 27% lower risk of advanced colorectal neoplasia than their non-active counterparts: systematic review and meta-analysis of observational studies. Br J Sports Med. 2020;54(10):582–91. · DOI
  4. Ahmad S, Shanmugasegaram S, Walker KL, Prince SA. Examining sedentary time as a risk factor for cardiometabolic diseases and their markers in south Asian adults: a systematic review. Int J Public Health. 2017;62(4):503–15. · DOI
  5. United Nations. Time to deliver: third UN high-level meeting on non-communicable diseases; 2018.

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Metadata

Authors
Dempsey, P. C., Biddle, S. J. H., Buman, M. P., Chastin, S., Ekelund, U., Friedenreich, C. M., Katzmarzyk, P. T., Leitzmann, M. F., Stamatakis, E., van der Ploeg, H. P., Willumsen, J., & Bull, F.
Affiliations
  • Baker Heart and Diabetes Institute (AU)
  • University of Southern Queensland (AU)
  • Arizona State University (US)
  • Glasgow Caledonian University (GB)
  • Norwegian Institute of Public Health (NO)
  • Alberta Health Services (CA)
  • Pennington Biomedical Research Center (US)
  • University of Regensburg (DE)
  • The University of Sydney (AU)
  • Amsterdam Public Health (NL)
  • World Health Organization (CH)
Corresponding author
Dempsey, Paddy C.
ORCID
Venue
International Journal of Behavioral Nutrition and Physical Activity
Publisher
Springer Science and Business Media LLC
Published
2020-11-26
Volume
17
Issue
1
Pages
151-151
ISSN
1479-5868 (ISSN-L)
DOI
10.1186/s12966-020-01044-0
PMC
PMC7691115
OpenAlex
W3107337658
Cited by
275
References
54
Citations by year
2026: 37 · 2025: 48 · 2024: 56 · 2023: 44 · 2022: 46 · 2021: 41 · 2020: 3
FWCI
20.15
Type
journal article
Language
en
Open access
Licence
Locations
  • International Journal of Behavioral Nutrition and Physical Activity (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
  • University of Southern Queensland ePrints (University of Southern Queensland) (acceptedVersion)
  • UniSA Research Outputs Repository (University of South Australia) (acceptedVersion, cc-by)
  • ResearchOnline (Glasgow Caledonian University) (acceptedVersion, cc-by)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion, cc-by)
  • Ghent University Academic Bibliography (Ghent University) (submittedVersion, cc-by)
  • Civil War Book Review (submittedVersion)
  • University of Regensburg Publication Server (University of Regensburg) (submittedVersion)
  • NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
  • Figshare (submittedVersion, cc-by)
  • Libraries and Cultural Resources (University of Calgary) (submittedVersion)
  • Pure Amsterdam UMC (submittedVersion, other-oa)
  • Apollo (University of Cambridge) (submittedVersion, cc-by)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Apollo (cc-by)
Funders
  • National Health and Medical Research Council of Australia (1110526 and 1194510, 1142685)
  • PAL Technologies
  • Public Health Agency of Canada
  • Government of Norway
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
  • Social Sciences › Human Factors and Ergonomics › Ergonomics and Musculoskeletal Disorders
  • Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Context-Aware Activity Recognition Systems
Keywords
sedentary behavior, physical activity guidelines, moderate-to-vigorous physical activity, cardiovascular mortality, cancer mortality, all-cause mortality, type 2 diabetes, evidence gaps, public health policy, AMSTAR 2, GRADE certainty of evidence
MeSH terms
Systematic Reviews as Topic, Adult, Cardiovascular Diseases, Diabetes Mellitus, Type 2, Humans, Neoplasms, Public Health, Risk Factors, World Health Organization, Exercise, Guidelines as Topic, Sedentary Behavior, Policy

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