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Cited by 490

The DOI matches its Crossref record; 273 of the 273 references it cites were found in a registry or an index.

Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches

Open access
Orth, Michael, Metzger, Philipp, Gerum, Sabine, Mayerle, Julia, Schneider, Günter, Belka, Claus, Schnurr, Maximilian, Lauber, Kirsten·2019·Radiation Oncology

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is a highly devastating disease with poor prognosis and rising incidence. Late detection and a particularly aggressive biology are the major challenges which determine therapeutic failure. In this review, we present the current status and the recent advances in PDAC treatment together with the biological and immunological hallmarks of this cancer entity. On this basis, we discuss new concepts combining distinct treatment modalities in order to improve therapeutic efficacy and clinical outcome - with a specific focus on protocols involving radio(chemo)therapeutic approaches.

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Crossref · 10.1186/s13014-019-1345-6

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Metadata

Authors
Orth, M., Metzger, P., Gerum, S., Mayerle, J., Schneider, G., Belka, C., Schnurr, M., & Lauber, K.
Venue
Radiation Oncology
Published
2019-08-08
Volume
14
Issue
1
Pages
141-141
ISSN
1748-717X (ISSN-L)
OpenAlex
W2968934833
Cited by
490
References
273
FWCI
18.68
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches. https://app.cochat.ai/papers/10.1186/s13014-019-1345-6
The paper
Orth, M., Metzger, P., Gerum, S., Mayerle, J., Schneider, G., Belka, C., Schnurr, M., & Lauber, K. (2019). Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches. Radiation Oncology. https://doi.org/10.1186/s13014-019-1345-6

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.