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Nanotechnology in cancer diagnosis: progress, challenges and opportunities

Zhang, Ye, Li, Maoyu, Gao, Xiaomei, Chen, Yongheng, Liu, Ting·2019·Journal of Hematology & Oncology
DOI 10.1186/s13045-019-0833-3PMC PMC6918551
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Abstract

In the fight against cancer, early detection is a key factor for successful treatment. However, the detection of cancer in the early stage has been hindered by the intrinsic limits of conventional cancer diagnostic methods. Nanotechnology provides high sensitivity, specificity, and multiplexed measurement capacity and has therefore been investigated for the detection of extracellular cancer biomarkers and cancer cells, as well as for in vivo imaging. This review summarizes the latest developments in nanotechnology applications for cancer diagnosis. In addition, the challenges in the translation of nanotechnology-based diagnostic methods into clinical applications are discussed.

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Fig. 1 Nanotechnology improves cancer detection and diagnosis
Fig. 1 Nanotechnology improves cancer detection and diagnosisCC BY · PubMed Central
Fig. 2 Schematic illustration of nanotechnology applications in cancer diagnosis
Fig. 2 Schematic illustration of nanotechnology applications in cancer diagnosisCC BY · PubMed Central

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Metadata

Authors
Zhang, Y., Li, M., Gao, X., Chen, Y., & Liu, T.
Venue
Journal of Hematology & Oncology
Publisher
Springer Science and Business Media LLC
Published
2019-12
Volume
12
Issue
1
ISSN
1756-8722
DOI
10.1186/s13045-019-0833-3
PMC
PMC6918551
Cited by
510
References
3
Language
en
Licence
Funders
  • National Natural Science Foundation of China (81372904, 81570537, 81902858, 81974074)
  • Natural Science Foundation of Hunan Province (2018JJ2664)
  • Postdoctoral Research Foundation of China (2017M620175)

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CoChat. (2026). Citation check: Nanotechnology in cancer diagnosis: progress, challenges and opportunities. https://app.cochat.ai/papers/10.1186/s13045-019-0833-3
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Zhang, Y., Li, M., Gao, X., Chen, Y., & Liu, T. (2019). Nanotechnology in cancer diagnosis: progress, challenges and opportunities. Journal of Hematology & Oncology. https://doi.org/10.1186/s13045-019-0833-3