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Cited by 266

The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.

Targeted therapy in advanced non-small cell lung cancer: current advances and future trends

Open access
Majeed, Umair, Manochakian, Rami, Zhao, Yujie, Lou, Yanyan·2021·Journal of Hematology & Oncology

Abstract

Lung cancer remains the leading cause of cancer-related mortality in both men and women in the US and worldwide. Non-small cell lung cancer is the most common variety accounting for 84% of the cases. For a subset of patients with actionable mutations, targeted therapy continues to provide durable responses. Advances in molecular and immunohistochemical techniques have made it possible to usher lung cancer into the era of personalized medicine, with the patient getting individualized treatment based on these markers. This review summarizes the recent advances in advanced NSCLC targeted therapy, focusing on first-in-human and early phase I/II clinical trials in patients with advanced disease. We have divided our discussion into different topics based on these agents' mechanisms of action. This article is aimed to be the most current review of available and upcoming targeted NSCLC treatment options. We will also summarize the currently available phase I/II clinical trial for NSCLC patients at the end of each section.

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Crossref · 10.1186/s13045-021-01121-2

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Metadata

Authors
Majeed, U., Manochakian, R., Zhao, Y., & Lou, Y.
Venue
Journal of Hematology & Oncology
Published
2021-07-08
Volume
14
Issue
1
Pages
108-108
ISSN
1756-8722 (ISSN-L)
OpenAlex
W3182048312
Cited by
266
References
81
FWCI
27.52
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Targeted therapy in advanced non-small cell lung cancer: current advances and future trends. https://app.cochat.ai/papers/10.1186/s13045-021-01121-2
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Majeed, U., Manochakian, R., Zhao, Y., & Lou, Y. (2021). Targeted therapy in advanced non-small cell lung cancer: current advances and future trends. Journal of Hematology & Oncology. https://doi.org/10.1186/s13045-021-01121-2

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.