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Cited by 388

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Antibiotic stewardship in the intensive care unit

Open access
Luyt, Charles-Edouard, Bréchot, Nicolas, Trouillet, Jean-Louis, Chastre, Jean·2014·Critical Care

Abstract

The rapid emergence and dissemination of antimicrobial-resistant microorganisms in ICUs worldwide constitute a problem of crisis dimensions. The root causes of this problem are multifactorial, but the core issues are clear. The emergence of antibiotic resistance is highly correlated with selective pressure resulting from inappropriate use of these drugs. Appropriate antibiotic stewardship in ICUs includes not only rapid identification and optimal treatment of bacterial infections in these critically ill patients, based on pharmacokinetic-pharmacodynamic characteristics, but also improving our ability to avoid administering unnecessary broad-spectrum antibiotics, shortening the duration of their administration, and reducing the numbers of patients receiving undue antibiotic therapy. Either we will be able to implement such a policy or we and our patients will face an uncontrollable surge of very difficult-to-treat pathogens.

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Crossref · 10.1186/s13054-014-0480-6

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Metadata

Authors
Luyt, C.-E., Bréchot, N., Trouillet, J.-L., & Chastre, J.
Venue
Critical Care
Published
2014-08-13
Volume
18
Issue
5
Pages
480-480
ISSN
1364-8535 (ISSN-L)
OpenAlex
W2169054220
Cited by
388
References
13
FWCI
15.11
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Antibiotic stewardship in the intensive care unit. https://app.cochat.ai/papers/10.1186/s13054-014-0480-6
The paper
Luyt, C.-E., Bréchot, N., Trouillet, J.-L., & Chastre, J. (2014). Antibiotic stewardship in the intensive care unit. Critical Care. https://doi.org/10.1186/s13054-014-0480-6

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.