The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Invasive lobular carcinoma of the breast: morphology, biomarkers and ’omics
Open accessAbstract
Invasive lobular carcinoma of the breast is the most common ‘special’ morphological subtype of breast cancer, comprising up to 15% of all cases. Tumours are generally of a good prognostic phenotype, being low histological grade and low mitotic index, hormone receptor positive and HER2, p53 and basal marker negative, and with a generally good response to endocrine therapy. Despite this, clinicians face countless challenges in the diagnosis and long-term management of patients, as they encounter a tumour that can be difficult to detect through screening, elicits a very invasive nature, a propensity for widespread metastatic colonisation and, consequently, in some studies a worse long-term poor outcome compared with invasive carcinoma of no special type. Here we review the morphological and molecular features that underpin the disparate biological and clinical characteristics of this fascinating tumour type.
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Cited by
Overcoming Endocrine Resistance in Breast Cancer
Hanker, A. B., Sudhan, D. R., & Arteaga, C. L. (2020) · Cancer Cell · doi:10.1016/j.ccell.2020.03.009 · Cited by 927
Towards targeting the breast cancer immune microenvironment
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Metadata
- Authors
- Reed, A. E. M., Kutasovic, J. R., Lakhani, S. R., & Simpson, P. T.
- Venue
- Breast Cancer Research
- Published
- 2015-01-30
- Volume
- 17
- Issue
- 1
- Pages
- 12-12
- ISSN
- 1465-5411 (ISSN-L)
- 1465-542X
- OpenAlex
- W2127342819
- Cited by
- 373
- References
- 64
- FWCI
- 18.35
- Type
- journal article
- Language
- en
- Open access
- gold
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- Reed, A. E. M., Kutasovic, J. R., Lakhani, S. R., & Simpson, P. T. (2015). Invasive lobular carcinoma of the breast: morphology, biomarkers and ’omics. Breast Cancer Research. https://doi.org/10.1186/s13058-015-0519-x
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