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Cited by 211

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HiCPlotter integrates genomic data with interaction matrices

Open access
Akdemir, Kadir Caner, Chin, Lynda·2015·Genome Biology

Abstract

Metazoan genomic material is folded into stable non-randomly arranged chromosomal structures that are tightly associated with transcriptional regulation and DNA replication. Various factors including regulators of pluripotency, long non-coding RNAs, or the presence of architectural proteins have been implicated in regulation and assembly of the chromatin architecture. Therefore, comprehensive visualization of this multi-faceted structure is important to unravel the connections between nuclear architecture and transcriptional regulation. Here, we present an easy-to-use open-source visualization tool, HiCPlotter, to facilitate juxtaposition of Hi-C matrices with diverse genomic assay outputs, as well as to compare interaction matrices between various conditions. https://github.com/kcakdemir/HiCPlotter.

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Metadata

Authors
Akdemir, K. C., & Chin, L.
Venue
Genome Biology
Published
2015-09-21
Volume
16
Issue
1
Pages
198-198
ISSN
  • 1465-6906 (ISSN-L)
  • 1474-760X
OpenAlex
W1915573037
Cited by
211
References
15
FWCI
4.25
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: HiCPlotter integrates genomic data with interaction matrices. https://app.cochat.ai/papers/10.1186/s13059-015-0767-1
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Akdemir, K. C., & Chin, L. (2015). HiCPlotter integrates genomic data with interaction matrices. Genome Biology. https://doi.org/10.1186/s13059-015-0767-1

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