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Cited by 145Genetic diversity and population structureGenetic Mapping and Diversity in Plants and AnimalsEvolution and Genetic Dynamics

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A major locus controls local adaptation and adaptive life history variation in a perennial plant

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Wang, Jing, Ding, Jihua, Tan, Biyue, Robinson, Kathryn M., Michelson, Ingrid H., Johansson, Anna, Nystedt, Björn, Scofield, Douglas G., Nilsson, Ove, Jansson, Stefan, Street, Nathaniel R., Ingvarsson, Pär K.·2018·Genome Biology
DOI 10.1186/s13059-018-1444-yPMC PMC5985590

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Abstract

BACKGROUND: The initiation of growth cessation and dormancy represent critical life-history trade-offs between survival and growth and have important fitness effects in perennial plants. Such adaptive life-history traits often show strong local adaptation along environmental gradients but, despite their importance, the genetic architecture of these traits remains poorly understood. RESULTS: We integrate whole genome re-sequencing with environmental and phenotypic data from common garden experiments to investigate the genomic basis of local adaptation across a latitudinal gradient in European aspen (Populus tremula). A single genomic region containing the PtFT2 gene mediates local adaptation in the timing of bud set and explains 65% of the observed genetic variation in bud set. This locus is the likely target of a recent selective sweep that originated right before or during colonization of northern Scandinavia following the last glaciation. Field and greenhouse experiments confirm that variation in PtFT2 gene expression affects the phenotypic variation in bud set that we observe in wild natural populations. CONCLUSIONS: Our results reveal a major effect locus that determines the timing of bud set and that has facilitated rapid adaptation to shorter growing seasons and colder climates in European aspen. The discovery of a single locus explaining a substantial fraction of the variation in a key life-history trait is remarkable, given that such traits are generally considered to be highly polygenic. These findings provide a dramatic illustration of how loci of large-effect for adaptive traits can arise and be maintained over large geographical scales in natural populations.

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  • By determining the timing of flowering, homologs of FLOWERING LOCUS T have been shown to facilitate ecotype formation in aspen and sunflower.

    “For example, by determining the timing of flowering, homologs of FLOWERING LOCUS T have been shown to facilitate ecotype formation in aspen (Wang et al., 2018) and sunflower (Todesco et al., 2020).”

    From Genomics of plant speciation (2023) · cites this paper as Wang et al., 2018

    The Backgrounds and Results identify PtFT2 as a FLOWERING LOCUS T homolog that affects bud-set timing and local adaptation in European aspen. They do not show that it determines flowering time or facilitates ecotype formation. The separate sunflower citation is not being assessed here. (LLM, conf=0.88)

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Cited by

Sorted by citations

  • Genomics of plant speciation

    Bock, D. G., Cai, Z., Elphinstone, C., González-Segovia, E., Hirabayashi, K., Huang, K., Keais, G. L., Kim, A., Owens, G. L., & Rieseberg, L. H. (2023) · Plant Communications · doi:10.1016/j.xplc.2023.100599 · Cited by 84

    “For example, by determining the timing of flowering, homologs of FLOWERING LOCUS T have been shown to facilitate ecotype formation in aspen (Wang et al., 2018) and sunflower (Todesco et al.”

Metadata

Authors
Wang, J., Ding, J., Tan, B., Robinson, K. M., Michelson, I. H., Johansson, A., Nystedt, B., Scofield, D. G., Nilsson, O., Jansson, S., Street, N. R., & Ingvarsson, P. K.
Affiliations
  • Umeå Plant Science Centre (SE)
  • Swedish University of Agricultural Sciences (SE)
  • Stora Enso (Sweden) (SE)
  • Uppsala University (SE)
Corresponding author
  • Wang, Jing
  • Ingvarsson, Pär K.
ORCID
Venue
Genome Biology
Publisher
Springer Science and Business Media LLC
Published
2018-06-04
Volume
19
Issue
1
Pages
72-72
ISSN
  • 1465-6906 (ISSN-L)
  • 1474-760X
DOI
10.1186/s13059-018-1444-y
PMC
PMC5985590
OpenAlex
W2805786695
Cited by
145
References
4
Citations by year
2026: 9 · 2025: 11 · 2024: 14 · 2023: 15 · 2022: 46 · 2021: 20 · 2020: 13 · 2019: 13 · 2018: 4
FWCI
7.80
Type
journal article
Language
en
Open access
Licence
Locations
  • Genome biology (publishedVersion, cc-by)
  • bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DiVA at Umeå University (Umeå University) (submittedVersion, other-oa)
  • Uppsala University Publications (Uppsala University) (submittedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • NORA - Norwegian Open Research Archives (submittedVersion, cc-by-nc-nd)
Funders
  • Vetenskapsrådet
  • Knut och Alice Wallenbergs Stiftelse
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
Keywords
local adaptation, Populus tremula, dormancy, growth cessation, latitudinal gradient, selective sweeps, genetic architecture, gene expression, cold adaptation, postglacial colonization
MeSH terms
Life History Traits, Adaptation, Physiological, Phenotype, Plants, Genetic Variation, Genes, Plant, Genome, Plant, Populus, Genetic Loci

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