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GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes

Open access
Jin, Jian-Jun, Yu, Wen-Bin, Yang, Jun-Bo, Song, Yu, dePamphilis, Claude W., Yi, Ting-Shuang, Li, De-Zhu·2020·Genome Biology

Abstract

GetOrganelle is a state-of-the-art toolkit to accurately assemble organelle genomes from whole genome sequencing data. It recruits organelle-associated reads using a modified “baiting and iterative mapping” approach, conducts de novo assembly, filters and disentangles the assembly graph, and produces all possible configurations of circular organelle genomes. For 50 published plant datasets, we are able to reassemble the circular plastomes from 47 datasets using GetOrganelle. GetOrganelle assemblies are more accurate than published and/or NOVOPlasty-reassembled plastomes as assessed by mapping. We also assemble complete mitochondrial genomes using GetOrganelle. GetOrganelle is freely released under a GPL-3 license ( https://github.com/Kinggerm/GetOrganelle ).

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Metadata

Authors
Jin, J.-J., Yu, W.-B., Yang, J.-B., Song, Y., dePamphilis, C. W., Yi, T.-S., & Li, D.-Z.
Venue
Genome Biology
Published
2020-09-10
Volume
21
Issue
1
Pages
241-241
ISSN
  • 1465-6906 (ISSN-L)
  • 1474-760X
OpenAlex
W3084201551
Cited by
3,991
References
3
FWCI
119.29
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes. https://app.cochat.ai/papers/10.1186/s13059-020-02154-5
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Jin, J.-J., Yu, W.-B., Yang, J.-B., Song, Y., dePamphilis, C. W., Yi, T.-S., & Li, D.-Z. (2020). GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes. Genome Biology. https://doi.org/10.1186/s13059-020-02154-5

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