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Cited by 417

The DOI matches its Crossref record; 204 of the 204 references it cites were found in a registry or an index.

Skin tissue regeneration for burn injury

Open access
Shpichka, Anastasia, Butnaru, Denis, Bezrukov, Evgeny A., Sukhanov, Roman B., Atala, Anthony, Burdukovskii, Vitaliy, Zhang, Yuanyuan, Timashev, Peter·2019·Stem Cell Research & Therapy

Abstract

The skin is the largest organ of the body, which meets the environment most directly. Thus, the skin is vulnerable to various damages, particularly burn injury. Skin wound healing is a serious interaction between cell types, cytokines, mediators, the neurovascular system, and matrix remodeling. Tissue regeneration technology remarkably enhances skin repair via re-epidermalization, epidermal-stromal cell interactions, angiogenesis, and inhabitation of hypertrophic scars and keloids. The success rates of skin healing for burn injuries have significantly increased with the use of various skin substitutes. In this review, we discuss skin replacement with cells, growth factors, scaffolds, or cell-seeded scaffolds for skin tissue reconstruction and also compare the high efficacy and cost-effectiveness of each therapy. We describe the essentials, achievements, and challenges of cell-based therapy in reducing scar formation and improving burn injury treatment.

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Crossref · 10.1186/s13287-019-1203-3

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Metadata

Authors
Shpichka, A., Butnaru, D., Bezrukov, E. A., Sukhanov, R. B., Atala, A., Burdukovskii, V., Zhang, Y., & Timashev, P.
Venue
Stem Cell Research & Therapy
Published
2019-03-15
Volume
10
Issue
1
Pages
94-94
ISSN
1757-6512 (ISSN-L)
OpenAlex
W2927716820
Cited by
417
References
204
FWCI
23.10
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Skin tissue regeneration for burn injury. https://app.cochat.ai/papers/10.1186/s13287-019-1203-3
The paper
Shpichka, A., Butnaru, D., Bezrukov, E. A., Sukhanov, R. B., Atala, A., Burdukovskii, V., Zhang, Y., & Timashev, P. (2019). Skin tissue regeneration for burn injury. Stem Cell Research & Therapy. https://doi.org/10.1186/s13287-019-1203-3

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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