The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.
Role of albumin in the preservation of endothelial glycocalyx integrity and the microcirculation: a review
Open accessAbstract
The endothelial glycocalyx comprises a complex layer of membrane-bound proteoglycans, secreted glycosaminoglycans, glycoproteins, glycolipids and bound plasma proteins such as albumin and antithrombin associated with the endothelial surface. The glycocalyx plays an important role in vascular homeostasis, regulating vascular permeability and cell adhesion, and acts as a mechanosensor for hemodynamic shear stresses; it also has antithrombotic and anti-inflammatory functions. Plasma proteins such as albumin are physiologically bound within the glycocalyx, thus contributing to stability of the layer. Albumin is the major determinant of plasma colloid osmotic pressure. In addition, albumin transports sphingosine-1-phosphate which has protective endothelial effects, acts as a free radical scavenger, and has immunomodulatory and anti-inflammatory effects. This review examines the physiological function of the endothelial glycocalyx and the role of human albumin in preserving glycocalyx integrity and the microcirculation.
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Cites
Intravenous Fluids and Acute Kidney Injury
Ding, X., Cheng, Z., & Qian, Q. (2017) · Blood Purification · doi:10.1159/000452702 · Cited by 6,827
Wiederschain, G. Y. (2009) · Biochemistry (Moscow) · doi:10.1134/s0006297909090156 · Cited by 4,083
The endothelial glycocalyx: composition, functions, and visualization
Reitsma, S., Slaaf, D. W., Vink, H., van Zandvoort, M. A. M. J., & oude Egbrink, M. G. A. (2007) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-007-0212-8 · Cited by 1,980
Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care
Myburgh, J. A., Finfer, S., Bellomo, R., Billot, L., Cass, A., Gattas, D., Glass, P., Lipman, J., Liu, B., McArthur, C., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1209759 · Cited by 1,687
Microvascular Blood Flow Is Altered in Patients with Sepsis
De Backer, D., Creteur, J., Preiser, J.-C., Dubois, M.-J., & Vincent, J.-L. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200109-016oc · Cited by 1,473
Albuminuria reflects widespread vascular damage: The Steno hypothesis
Deckert, T., Feldt-Rasmussen, B., Borch-Johnsen, K., Jensen, T., & Kofoed-Enevoldsen, A. (1989) · Diabetologia · doi:10.1007/bf00285287 · Cited by 1,400
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury
Kashani, K., Al-Khafaji, A., Ardiles, T., Artigas, A., Bagshaw, S. M., Bell, M., Bihorac, A., Birkhahn, R., Cely, C. M., Chawla, L. S., et al. (2013) · Critical Care · doi:10.1186/cc12503 · Cited by 1,362
Self-citationLeon, B. M. (2015) · World Journal of Diabetes · doi:10.4239/wjd.v6.i13.1246 · Cited by 1,215
The Structure and Function of the Endothelial Glycocalyx Layer
Weinbaum, S., Tarbell, J. M., & Damiano, E. R. (2007) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.9.060906.151959 · Cited by 1,198
Microvascular fluid exchange and the revised Starling principle
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Metadata
- Authors
- Aldecoa, C., Llau, J. V., Nuvials, X., & Artigas, A.
- Venue
- Annals of Intensive Care
- Publisher
- Elsevier BV
- Published
- 2020-06-22
- Volume
- 10
- Issue
- 1
- Pages
- 85-85
- ISSN
- 2110-5820 (ISSN-L)
- OpenAlex
- W3036648905
- Cited by
- 253
- References
- 98
- FWCI
- 9.60
- Type
- journal article
- Language
- en
- Open access
- gold
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- Aldecoa, C., Llau, J. V., Nuvials, X., & Artigas, A. (2020). Role of albumin in the preservation of endothelial glycocalyx integrity and the microcirculation: a review. Annals of Intensive Care. https://doi.org/10.1186/s13613-020-00697-1
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
