Interpersonal psychotherapy for perinatal women: a systematic review and meta-analysis protocol
Open accessAbstract
Background: Interpersonal psychotherapy (IPT) is an intervention that has established efficacy in the prevention and treatment of depressive disorders. Previous systematic reviews have not evaluated the effectiveness of IPT on symptoms of stress, anxiety, depression, quality of life, relationship satisfaction/quality, social supports, and an improved psychological sense of well-being. There is limited data regarding factors that moderate and mediate the effectiveness of IPT including the timing of the intervention or the mode of delivery of IPT intervention. The objective of this systematic review and meta-analysis is to evaluate the effectiveness, feasibility, and acceptability of IPT interventions to treat perinatal psychological distress and to summarize the evidence on predictors, mediators, and moderators of IPT. Methods: We will include peer-reviewed studies that recruited perinatal women. The search strategy will involve the following databases: MEDLINE (Ovid), EMBASE (Ovid), PsycINFO (Ovid), Cochrane Central Register of Controlled Trials (Ovid), CINAHL with Full Text (EBSCO), Social Work Abstracts (EBSCO), SocINDEX with Full Text (EBSCO), Academic Search Complete (EBSCO), Family & Society Studies Worldwide (EBSCO), Family Studies Abstracts (EBSCO), and Scopus. Study inclusion criteria include (1) randomized controlled trials, quasi-experimental studies, and pre-post studies that evaluated the effectiveness of IPT; (2) qualitative studies that evaluated feasibility and acceptability of IPT; (3) study sample included and analyzed perinatal women; and (4) publication language was English. Using pilot-tested screening and data extraction forms, two reviewers will independently review studies in three steps: (1) abstract/title screening, (2) full-text screening of potentially accepted studies, and (3) data extraction of accepted studies. Disagreements will be resolved by a third reviewer. Studies will be aggregated for meta-synthesis and meta-analysis should the data allow for this. Two independent reviewers will grade methodological quality. Discussion: Findings from this review will inform future development and implementation of IPT intervention research for perinatal women. Identifying key factors of successful IPT interventions will inform intervention design and adaptation of IPT interventions to increase the likelihood that perinatal women will engage in and benefit from IPT interventions. This review will also identify key considerations for increasing the effectiveness of IPT interventions during the perinatal period. Systematic review registration: PROSPERO CRD42019114292
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Alongside medication, interpersonal therapy and cognitive behavioral therapy are the best-studied and most effective ways to treat and prevent perinatal mood disorders.
“It is important to recognize that in addition to pharmacologic treatment, interpersonal therapy (IPT) and cognitive behavioral therapy (CBT) interventions are the most well studied and most effective treatment85,86 and prevention strategies87 for perinatal mood disorders.”
From Prevalence of Depression or Anxiety During Antepartum Hospitalizations for Obstetric Complications (2021) · cites this paper as [85]
The Background (page not provided) describes promising perinatal IPT studies, including treatment of depression during pregnancy and prevention of postpartum depression. It says CBT and IPT have been studied extensively and appear equally effective for depression in adult populations, but it does not establish that both are the most-studied or most-effective treatment and prevention strategies for perinatal mood disorders broadly. (LLM, conf=0.87)
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- Authors
- Bright, K. S., Charrois, E. M., Mughal, M. K., Wajid, A., McNeil, D., Stuart, S., Hayden, K. A., & Kingston, D.
- Affiliations
- University of Calgary (CA)
- Alberta Health Services (CA)
- University of Iowa (US)
- Corresponding author
- Bright, Katherine S.
- ORCID
- Venue
- Systematic Reviews
- Published
- 2019-10-29
- Volume
- 8
- Issue
- 1
- Pages
- 248-248
- ISSN
- 2046-4053 (ISSN-L)
- PMC
- PMC6819345
- OpenAlex
- W2982647013
- Cited by
- 13
- References
- 63
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 4 · 2023: 1 · 2022: 2 · 2021: 2 · 2020: 2
- FWCI
- 0.25
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Systematic Reviews (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Libraries and Cultural Resources (University of Calgary) (acceptedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Libraries and Cultural Resources (University of Calgary) (submittedVersion)
- Funders
- University of Calgary
- Alberta Children's Hospital Research Institute
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- interpersonal psychotherapy, perinatal women, perinatal depression, anxiety, stress, quality of life, relationship satisfaction, social support, well-being, intervention timing, mode of delivery, feasibility and acceptability
- MeSH terms
- Systematic Reviews as Topic, Interpersonal Psychotherapy, Psychological Distress, Anxiety, Depressive Disorder, Female, Humans, Pregnancy, Quality of Life, Meta-Analysis as Topic, Perinatal Care, Parturition
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