Cited by 147Personality Disorders and PsychopathologyClinical practice guidelines implementationPersonality Traits and Psychology

The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index; none of the 31 sources its claims cite is checked for support yet.

European guidelines for personality disorders: past, present and future

Open access

Abstract

Personality disorders (PD) are common and burdensome mental disorders. The treatment of individuals with PD represents one of the more challenging areas in the field of mental health and health care providers need evidence-based recommendations to best support patients with PDs. Clinical guidelines serve this purpose and are formulated by expert consensus and/or systematic reviews of the current evidence. In this review, European guidelines for the treatment of PDs are summarized and evaluated. To date, eight countries in Europe have developed and published guidelines that differ in quality with regard to recency and completeness, transparency of methods, combination of expert knowledge with empirical data, and patient/service user involvement. Five of the guidelines are about Borderline personality disorder (BPD), one is about antisocial personality disorder and three concern PD in general. After evaluating the methodological quality of the nine European guidelines from eight countries, results in the domains of diagnosis, psychotherapy and pharmacological treatment of PD are discussed. Our comparison of guidelines reveals important contradictions between recommendations in relation to diagnosis, length and setting of treatment, as well as the use of pharmacological treatment. All the guidelines recommend psychotherapy as the treatment of first choice. Future guidelines should rigorously follow internationally accepted methodology and should more systematically include the views of patients and users.

Overview

AI snapshot

Written from the paper’s full text.

TL;DR

This review summarizes and evaluates European clinical guidelines for personality disorders, identifying nine guidelines from eight countries and comparing their recommendations on diagnosis, psychotherapy, and pharmacological treatment. It finds broad agreement that psychotherapy is first-choice treatment but important contradictions in diagnosis, treatment length/setting, and medication use, and calls for more rigorous, patient-inclusive future guidelines.

Key findings

  • Nine European guidelines from eight countries were identified: five on borderline personality disorder (BPD), one on antisocial personality disorder (ASPD), and three on personality disorders in general.
  • All guidelines recommend psychotherapy as the treatment of first choice; for BPD there is broad consensus that outpatient psychotherapy should be primary, but recommendations on length and setting conflict—e.g., Danish guidelines allow short-term (< 12 months) or long-term (≥ 12 months) psychotherapy, while British guidelines warn against brief interventions of less than 3 months, and Swiss recommendations describe outpatient psychotherapy 1–2 sessions per week over 1–3 years.
  • Pharmacological treatment is generally not recommended as the primary intervention for PD; it is mainly for comorbid disorders or brief crisis use, though Swiss, Finnish, and Dutch guidelines suggest medication may target specific BPD dimensions such as anger, impulsivity, or negative mood, while British guidelines say not to use drug treatment specifically for BPD or its individual symptoms and limit crisis sedative use to no longer than 1 week.
  • Diagnosis recommendations show some consensus on semi-structured interviews, but Swedish guidelines state such interviews alone are insufficient and recommend the LEAD principle, Danish guidelines do not recommend routine screening in primary care, Swiss guidelines recommend screening for specific symptoms and differential diagnoses, and only the Swiss guideline directly addresses severity.

Methods

  • Narrative review/overview of European PD guidelines known to the authors, organized by geographical region and evaluated with attention to AGREE domains, especially rigour of development and applicability.
  • Guidelines covered include Sweden (2017), Finland (2015), Denmark (2016), Germany (2009), the Netherlands (2008), the UK (2009 BPD and ASPD), Switzerland (2018), and Catalonia/Spain (2011); no Norwegian national clinical guidelines for PDs currently exist.
  • The authors compared recommendations across three main areas—diagnosis, psychological treatment, and pharmacological treatment—using tables and qualitative synthesis; they did not perform formal AGREE scoring.

Limitations

  • Stated: the authors acknowledge that using the AGREE system would have been a more systematic approach for guideline quality appraisal, but this was not considered feasible due to language barriers and the unfunded nature of the project; the AGREE manual recommends at least 2 and preferably 4 appraisers for reliable rating.
  • Stated: existing guidelines vary in quality, recency, completeness, transparency of methods, combination of expert knowledge with empirical data, and patient/service user involvement; many recommendations are based on clinical/expert consensus or very low levels of evidence, and implementation and severity are generally neglected.
  • Evident from the text: this is a narrative overview rather than a systematic review, with no formal quality scoring, and the guideline set is limited to those the authors were aware of, so language and awareness barriers may have excluded relevant European guidelines.

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Integrity signals

Registry

Crossref · 10.1186/s40479-019-0106-3

Cites

26 of 26 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

56 No basis given · 31 Not checked yet · 15 Own result · 6 Own interpretation · 1 Own method

Verify all 31 references — free account

Show all 36 claims

  • Probably not a substantial claim. 57
  • It may state two separate claims as one. 29
  • The quote only partly states this claim. 1
73 of 73
  • The paper relies on this without support.

    Recommendations in diagnosis and general treatment are independent of national health systems and thus generalizable to the whole of Europe.

    “These areas were chosen because recommendations in diagnosis and general treatment should be independent of national health systems and thus be generalizable to the whole of Europe.”
  • The paper relies on this without support.

    Widespread comorbidity is often seen in people with PDs, including several comorbid PDs and comorbidity with other clinical syndromes such as anxiety, depression, PTSD and substance use disorders.

    “the widespread comorbidity often seen in people with PDs, not only in terms of several comorbid PDs, but also in terms of comorbidity with other clinical syndromes, such as anxiety, depression, post-traumatic stress disorder and substance use disorders”
  • The paper relies on this without support.

    People with multiple disorders often receive too many or conflicting therapies.

    “People with multiple disorders often receive too many or conflicting therapies”
  • The paper relies on this without support.

    Guidelines should base their recommendations on an evidence-based paradigm.

    “guidelines should base their recommendations on an evidence-based paradigm”
  • The paper relies on this without support.

    Patients' needs and values are important sources of knowledge for clinical guidelines.

    “Patients’ needs, and values are important sources of such knowledge”
  • The paper relies on this without support.

    The strongest recommendations of guidelines stem from randomized controlled trials.

    “their strongest recommendations stem from randomized controlled trials”
  • The paper relies on this without support.

    DSM-5 and ICD-11 focus a great deal on severity in the diagnosis of PDs.

    “The recently published DSM-5, with its Alternative Model for PDs as well as the upcoming ICD-11, focuses a great deal on severity in the diagnosis of PDs.”
7 of 7

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2 of 2

Citations

Cites

Show all 26 references

Research works printed but not linked: 3

  1. Vind, AB, et al. National klinisk retningslinje for behandling af emotionel ustabil personlighedsstruktur, borderline type. 2015.
  2. Committee DPMG. Dutch multidisciplinary guideline for personality disorders. Utrecht: Trimbos-institute; 2008.
  3. Instituut, T, Zorgstandaard persoonlijkheidsstoornissen: Kwaliteitsontwikkeling GGZ [Care standard personality disorders: Quality development mental health care]. 2017.

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Items 101–147 of 147

Metadata

Authors
Simonsen, S., Bateman, A., Bohus, M., Dalewijk, H. J., Doering, S., Kaera, A., Moran, P., Renneberg, B., Ribaudi, J. S., Taubner, S., Wilberg, T., & Mehlum, L.
Affiliations
  • University of Copenhagen (DK)
  • Heidelberg University (DE)
  • Medical University of Vienna (AT)
  • Kanta-Hämeen Keskussairaala (FI)
  • University of Bristol (GB)
  • Freie Universität Berlin (DE)
  • Oslo University Hospital (NO)
  • University of Oslo (NO)
Corresponding author
Simonsen, Sebastian
Venue
Borderline Personality Disorder and Emotion Dysregulation
Published
2019-05-21
Volume
6
Issue
1
Pages
9-9
ISSN
2051-6673 (ISSN-L)
OpenAlex
W2947641077
Cited by
147
References
26
Citations by year
2026: 11 · 2025: 31 · 2024: 27 · 2023: 22 · 2022: 27 · 2021: 18 · 2020: 10 · 2019: 1
FWCI
2.22
Type
journal article
Language
en
Open access
Locations
  • Borderline Personality Disorder and Emotion Dysregulation (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • heiDOK (Heidelberg University) (acceptedVersion, other-oa)
  • Dipòsit Digital de Documents de la UAB (Universitat Autònoma de Barcelona) (submittedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • Explore Bristol Research (submittedVersion, cc-by)
  • Bristol Research (University of Bristol) (submittedVersion, cc-by)
  • NORA - Norwegian Open Research Archives (submittedVersion, cc-by)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
  • Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
Keywords
personality disorders, borderline personality disorder, antisocial personality disorder, psychotherapy, pharmacotherapy, diagnosis, guideline methodological quality, European guidelines

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