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Iron deficiency decreases renal 25-hydroxyvitamin D3-1α-hydroxylase activity and bone formation in rats
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“Azizi-Soleiman [1] and Katsumata et al. [39] emphasize that the reason for this might be the degree of iron deficiency.”
From The Association between Iron and Vitamin D Status in Female Elite Athletes (2018) · cites this paper as [39]
In the citing paper
“conversion of cholecalciferol to the biologically active form, calcitriol (1,25-dihydroxyvitamin D3) requires two steps of hydroxylation—the first in the liver and the second in the kidney—which depend on enzymes containing heme, i.e., cytochromes P450 (CYP2R1 and CYP27B1 respectively) [38,39].”
From The Association between Iron and Vitamin D Status in Female Elite Athletes (2018) · cites this paper as [39]
In the citing paper
“This important role of iron in the synthesis of vitamin D was clearly confirmed by Katsumata et al. [39], who reported that dietary iron deficiency in rats caused diminished 1α-hydroxylase activity, leading to a decrease in serum 1,25-dihydroxyvitamin D3 concentration.”
From The Association between Iron and Vitamin D Status in Female Elite Athletes (2018) · cites this paper as [39]
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Research works printed but not linked: 23
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- Katsumata S, Katsumata-Tsuboi R, Uehara M, Suzuki K. Severe iron deficiency decreases both bone formation and bone resorption in rats. J Nutr. 2009;139:238–43. · DOI
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Cited by
The Association between Iron and Vitamin D Status in Female Elite Athletes
Malczewska-Lenczowska, J., Sitkowski, D., Surała, O., Orysiak, J., Szczepańska, B., & Witek, K. (2018) · Nutrients · doi:10.3390/nu10020167 · Cited by 76
Metadata
- Authors
- Katsumata, S., Katsumata, R., Matsumoto, N., Inoue, H., Takahashi, N., & Uehara, M.
- Venue
- BMC Nutrition
- Published
- 2016-06-07
- Volume
- 2
- Issue
- 1
- ISSN
- 2055-0928
- Cited by
- 21
- References
- 0
- Language
- en
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Cite CoChat for the checks on this page, and the paper for its own findings.
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- CoChat. (2026). Citation check: Iron deficiency decreases renal 25-hydroxyvitamin D3-1α-hydroxylase activity and bone formation in rats. https://app.cochat.ai/papers/10.1186/s40795-016-0072-8
- The paper
- Katsumata, S., Katsumata, R., Matsumoto, N., Inoue, H., Takahashi, N., & Uehara, M. (2016). Iron deficiency decreases renal 25-hydroxyvitamin D3-1α-hydroxylase activity and bone formation in rats. BMC Nutrition. https://doi.org/10.1186/s40795-016-0072-8
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
