Promoting adherence to treatment for latent TB infection through mobile phone text messaging: study protocol for a pilot randomized controlled trial
Open accessAbstract
BACKGROUND: (LTBI). Patient adherence to LTBI treatment is currently poor given that individuals show no symptoms of illness and may not feel that they are at risk of developing active tuberculosis (TB). Short text messages can serve as a simple reminder to take medications and address barriers to adherence such as forgetfulness and lack of social support. METHODS/DESIGN: We aim to determine the feasibility and acceptability of text reminders for improving adherence in latent TB patients using a randomized controlled single-blinded trial, measuring adherence through an increase in treatment completion rates. Forty adult LTBI participants will be randomized to either text messages plus phone call reminders or phone call reminders only (usual care). Recruitment, retention, and study acceptability will be assessed as primary outcomes. DISCUSSION: This pilot study will examine the feasibility of using text messaging for increasing adherence to treatment for latent tuberculosis infection. The study will allow for evaluation of process measures and challenges and development of a model for scaling up an effectiveness trial for increasing treatment adherence. TRIAL REGISTRATION: NCT02690818 (Clinical Trials.gov).
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Mobile phones can deliver programs to support behavioral change.
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From Assessing the Cross-Cultural Adaptation and Translation of a Text-Based Mobile Smoking Cessation Program in Samoa (TXTTaofiTapaa): Pilot Study (2018) · cites this paper as [1]
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- Authors
- Oren, E., Bell, M. L., Garcia, F., Perez-Velez, C., & Gerald, L. B.
- Affiliations
- University of Arizona (US)
- Corresponding author
- Oren, Eyal
- Venue
- Pilot and Feasibility Studies
- Published
- 2017-03-13
- Volume
- 3
- Issue
- 1
- Pages
- 15-15
- ISSN
- 2055-5784 (ISSN-L)
- PMC
- PMC5346839
- OpenAlex
- W2593186258
- Cited by
- 20
- References
- 53
- Citations by year
- 2025: 1 · 2023: 1 · 2022: 5 · 2021: 1 · 2020: 2 · 2019: 5 · 2018: 3 · 2017: 2
- FWCI
- 5.32
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Pilot and Feasibility Studies (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- American Lung Association (Social Behavioral Research Grant)
- Topics
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Keywords
- latent tuberculosis infection, medication adherence, SMS reminders, mobile phone reminders, phone call reminders, treatment completion, feasibility and acceptability, participant recruitment and retention, social support
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