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Cited by 140Skin Protection and AgingMedicinal Plant ResearchPhytochemistry and Biological Activities

In vitro screening of elastase, collagenase, hyaluronidase, and tyrosinase inhibitory and antioxidant activities of 22 halophyte plant extracts for novel cosmeceuticals

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Jiratchayamaethasakul, Chanipa, Ding, Yuling, Hwang, Ouibo, Im, Seung-Tae, Jang, Yebin, Myung, Seung-Won, Lee, Jeong Min, Kim, Hyun-Soo +2 more·2020·Fisheries and Aquatic Sciences
DOI 10.1186/s41240-020-00149-8
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Abstract

Halophyte plant (HPs), a salt-resistant flora, has been reported to provide several health benefits, but the knowledge of its cosmeceutical potential is still ambiguous. Here, 70% ethanol extracts of 22 HPs collected from along the coast of South Korea were investigated for their potentials of antioxidant, anti-aging, and whitening properties for use as materials in novel cosmeceuticals. Antioxidant activities were determined by DPPH (1,1-diphenyl-2-pricrylhydrazyl) free radical and hydrogen peroxide scavenging assays, and skin aging-related enzyme activities (anti-elastase, anti-collagenase, anti-hyaluronidase, and anti-tyrosinase) were evaluated by using the spectrophotometric method. Among the 22 HPs, we found that Ischaemum antephoroides f. coreana and Atriplex gmelinii extracts presented the strongest scavenging effects against DPPH free radical and hydrogen peroxide, respectively. Our finding additionally suggested that Salicornia europaea extract might provide a major source of anti-elastase and anti-hyaluronidase; meanwhile, Rosa rugosa extract showed the highest anti-collagenase effect. Furthermore, the highest tyrosinase inhibitory activity was possessed by Spartina anglica extract . These findings may suggest that halophyte plants showing biological activities may be potent inhibitors of tyrosinase, elastase, collagenase, and hyaluronidase and could be useful for application in cosmeceuticals.

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  • Eicosanyl caffeate and docosyl caffeate from G. glabra roots have potent elastase inhibitory activity with IC50 values of 0.99 μg/mL and 1.4 μg/mL, respectively.

    “Moreover, eicosanyl caffeate and docosyl caffeate, two long-chain caffeoyl esters isolated by ethyl acetate extract of G. glabra roots displayed by a spectrophotometric assay a potent elastase inhibitory activity, an additional target to prevent aging and wrinkles formation [60], with IC 50 values of 0.99 µg/mL and 1.4 µg/mL, respectively [61].”

    From Licorice (Glycyrrhiza glabra, G. uralensis, and G. inflata) and Their Constituents as Active Cosmeceutical Ingredients (2022) · cites this paper as [60]

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Authors
Jiratchayamaethasakul, C., Ding, Y., Hwang, O., Im, S.-T., Jang, Y., Myung, S.-W., Lee, J. M., Kim, H.-S., Ko, S.-C., & Lee, S.-H.
Affiliations
  • Soonchunhyang University (KR)
  • Marine Biodiversity Institute of Korea (KR)
Corresponding author
Lee, Seung-Hong
ORCID
Venue
Fisheries and Aquatic Sciences
Publisher
The Korean Society of Fisheries and Aquatic Science
Published
2020-03-06
Volume
23
Issue
1
ISSN
  • 2234-1749 (ISSN-L)
  • 2234-1757
DOI
10.1186/s41240-020-00149-8
OpenAlex
W3028767857
Cited by
140
References
0
Citations by year
2026: 23 · 2025: 29 · 2024: 25 · 2023: 26 · 2022: 25 · 2021: 10 · 2020: 1
FWCI
11.31
Type
journal article
Language
en
Open access
Licence
Locations
  • Fisheries and aquatic sciences (publishedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • National Research Foundation
  • Soonchunhyang University
  • National Research Foundation of Korea (2019R1A5A8083404)
  • Ministry of Science and ICT, South Korea
Topics
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
Keywords
halophytes, cosmeceuticals, antioxidant activity, tyrosinase inhibition, collagenase inhibition, elastase inhibition, hyaluronidase inhibition, skin aging, skin lightening, Salicornia europaea, Rosa rugosa, Spartina anglica, DPPH radical scavenging, hydrogen peroxide scavenging, plant extracts

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