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Graduate Training at the Interface of Computational and Experimental Biology: An Outcome Report from a Partnership of Volunteers between a University and a National Laboratory
Open accessAbstract
Leading voices in the biological sciences have called for a transformation in graduate education leading to the PhD degree. One area commonly singled out for growth and innovation is cross-training in computational science. In 1998, the University of Tennessee (UT) founded an intercollegiate graduate program called the UT-ORNL Graduate School of Genome Science and Technology in partnership with the nearby Oak Ridge National Laboratory. Here, we report outcome data that attest to the program’s effectiveness in graduating computationally enabled biologists for diverse careers. Among 77 PhD graduates since 2003, the majority came with traditional degrees in the biological sciences, yet two-thirds moved into computational or hybrid (computational–experimental) positions. We describe the curriculum of the program and how it has changed. We also summarize how the program seeks to establish cohesion between computational and experimental biologists. This type of program can respond flexibly and dynamically to unmet training needs. In conclusion, this study from a flagship, state-supported university may serve as a reference point for creating a stable, degree-granting, interdepartmental graduate program in computational biology and allied areas.
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Metadata
- Authors
- von Arnim, A. G., & Missra, A.
- Affiliations
- Oak Ridge National Laboratory (US)
- Corresponding author
- von Arnim, Albrecht G.
- Venue
- CBE—Life Sciences Education
- Published
- 2017-12
- Volume
- 16
- Issue
- 4
- Pages
- ar61
- ISSN
- 1931-7913 (ISSN-L)
- PMC
- PMC5749963
- OpenAlex
- W2770242051
- Cited by
- 8
- References
- 33
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 1 · 2021: 3 · 2019: 2
- FWCI
- 0.22
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc-sa
- Locations
- CBE—Life Sciences Education (publishedVersion, cc-by-nc-sa)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
- Funders
- National Science Foundation (1546402, 1456988)
- National Institutes of Health
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genetics, Bioinformatics, and Biomedical Research
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Interdisciplinary Research and Collaboration
- Social Sciences › Education › Doctoral Education Challenges and Solutions
- Keywords
- computational biology education, graduate education, doctoral programs, curriculum development, career outcomes, Oak Ridge National Laboratory, University of Tennessee
- MeSH terms
- Career Choice, Cooperative Behavior, Curriculum, Demography, Education, Graduate, Female, Humans, Laboratories, Male, Universities, Volunteers, Computational Biology, Research Report
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