The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Outcome selection bias in meta-analysis
Abstract
Publication bias has been previously identified as a threat to the validity of a meta-analysis. Recently, new evidence has documented an additional threat to validity, the selective reporting of trial outcomes within published studies. Several diseases have several possible measures of outcome. Some articles might report only a selection of those outcomes, perhaps those with statistically significant results. In this article, we review this problem while addressing the questions: what is within-study selective reporting? how common is it? why is it done? how can it mislead? how can it be detected?, and finally, what is the solution? We recommend that both publication bias and selective reporting should be routinely investigated in systematic reviews.
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Duval, S., & Tweedie, R. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00455.x · Cited by 14,099
Journal of the American Statistical Association
Fildes, R. A. (1989) · International Journal of Forecasting · doi:10.1016/0169-2070(89)90106-4 · Cited by 3,956
誠一, 市. (2004) · The Journal of AIDS Research · doi:10.11391/aidsr1999.6.104 · Cited by 3,233
Publication bias in clinical research
Easterbrook, P. J., Gopalan, R., Berlin, J. A., & Matthews, D. R. (1991) · The Lancet · doi:10.1016/0140-6736(91)90201-y · Cited by 3,109
A Nonparametric “Trim and Fill” Method of Accounting for Publication Bias in Meta-Analysis
Duval, S., & Tweedie, R. (2000) · Journal of the American Statistical Association · doi:10.1080/01621459.2000.10473905 · Cited by 2,955
Statistical Methods for Meta-Analysis
(1985) · Elsevier eBooks · doi:10.1016/c2009-0-03396-0 · Cited by 2,570
Chan, A.-W., Hróbjartsson, A., Haahr, M. T., Gøtzsche, P. C., & Altman, D. G. (2004) · JAMA · doi:10.1001/jama.291.20.2457 · Cited by 1,845
Self-citationSystematic Reviews in Health Care: Meta‐Analysis in Context
(2001) · doi:10.1002/9780470693926 · Cited by 1,693
Cochrane Injuries Group Albumin ReviewersWhy albumin may not work
Berger, A. (1998) · BMJ · doi:10.1136/bmj.317.7153.235 · Cited by 1,080
Consequences of prejudice against the null hypothesis.
Greenwald, A. G. (1975) · Psychological Bulletin · doi:10.1037/h0076157 · Cited by 1,022
Research works printed but not linked: 1
- Hutton JL, 2000, Applied Statistics, 49, 359
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Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164
“For example, in a particular disease, if one of two linked outcomes is reported but the other is not, then one should question whether the latter has been selectively omitted [121,122].”
BackgroundSelf-citationCochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
(2008) · doi:10.1002/9780470712184 · Cited by 25,048
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gotzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · BMJ · doi:10.1136/bmj.b2700 · Cited by 17,648
Self-citationShamseer, L., Moher, D., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., Stewart, L. A., & the PRISMA-P Group (2015) · BMJ · doi:10.1136/bmj.g7647 · Cited by 13,120
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.006 · Cited by 10,578
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Metadata
- Authors
- Williamson, P. R., Gamble, C., Altman, D. G., & Hutton, J. L.
- Affiliations
- University of Liverpool (GB)
- University of Oxford (GB)
- University of Warwick (GB)
- Venue
- Statistical Methods in Medical Research
- Publisher
- SAGE Publications
- Published
- 2005-10
- Volume
- 14
- Issue
- 5
- Pages
- 515-524
- ISSN
- 0962-2802 (ISSN-L)
- 1477-0334
- OpenAlex
- W2056439589
- Cited by
- 188
- References
- 35
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 4 · 2023: 10 · 2022: 4 · 2021: 18 · 2020: 7 · 2019: 9 · 2018: 6 · 2017: 9 · 2016: 9 · 2015: 10 · 2014: 8 · 2013: 11 · 2012: 8
- FWCI
- 10.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Statistical Methods in Medical Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Keywords
- selective reporting, publication bias, meta-analysis validity, systematic reviews, trial outcomes
- MeSH terms
- Clinical Trials as Topic, United Kingdom, Humans, Publications, Meta-Analysis as Topic, Reproducibility of Results, Bias, Outcome Assessment, Health Care
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