The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Patterns of Cerebral Blood Flow in Schizophrenia
Abstract
Positron emission tomography was used to study the relationship between rCBF and symptom profiles in 30 schizophrenic patients. Factor analysis confirmed that the symptoms segregated into three syndromes – psychomotor poverty, disorganisation, and reality distortion – described previously. Analysis of the correlations between syndrome scores and rCBF revealed that each syndrome was associated with a specific pattern of perfusion in paralimbic and association cortex, and in related subcortical nuclei. The study confirmed predictions that psychomotor poverty and disorganisation are associated with altered perfusion at different loci in the pre-frontal cortex, and reality distortion with altered perfusion in the medial temporal lobe. The perfusion patterns suggest that the abnormalities of brain function underlying each of the three syndromes are not confined to single loci, but involve distributed neuronal networks.
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Citations
Cites
Pardo, J. V., Pardo, P. J., Janer, K. W., & Raichle, M. E. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.1.256 · Cited by 1,495
Bogerts, B. (1985) · Archives of General Psychiatry · doi:10.1001/archpsyc.1985.01790310046006 · Cited by 880
Experiences of alien control in schizophrenia reflect a disorder in the central monitoring of action
Frith, C. D., & Done, D. J. (1989) · Psychological Medicine · doi:10.1017/s003329170001240x · Cited by 551
Self-citation
Cited by
Basal ganglia and cerebellar loops: motor and cognitive circuits
Middleton, F. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00040-5 · Cited by 1,940
Neurobiology of emotion perception II: implications for major psychiatric disorders
Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00171-9 · Cited by 1,736
The neuropathology of schizophrenia
Harrison, P. J. (1999) · Brain · doi:10.1093/brain/122.4.593 · Cited by 1,677
Dopamine and the regulation of cognition and attention
Nieoullon, A. (2002) · Progress in Neurobiology · doi:10.1016/s0301-0082(02)00011-4 · Cited by 1,131
Aberrant “Default Mode” Functional Connectivity in Schizophrenia
Garrity, A. G., Pearlson, G. D., McKiernan, K., Lloyd, D., Kiehl, K. A., & Calhoun, V. D. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.3.450 · Cited by 1,114
Metadata
- Authors
- Liddle, P. F., Friston, K. J., Frith, C. D., Hirsch, S. R., Jones, T., & Frackowiak, R. S. J.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 1992-02
- Volume
- 160
- Issue
- 2
- Pages
- 179-186
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2169365717
- Cited by
- 900
- References
- 3
- FWCI
- 40.95
- Type
- journal article
- Language
- en
- Open access
- closed
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- Liddle, P. F., Friston, K. J., Frith, C. D., Hirsch, S. R., Jones, T., & Frackowiak, R. S. J. (1992). Patterns of Cerebral Blood Flow in Schizophrenia. British Journal of Psychiatry. https://doi.org/10.1192/bjp.160.2.179
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