The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Efficacy and safety of acamprosate in the treatment of detoxified alcohol-dependent patients: A 90-day placebo-controlled dose-finding study
Abstract
Background: Acamprosate is a newly registered drug that appears to reduce alcohol-drinking in both animal models and clinical conditions. Method: In order to assess the efficacy and safety of the drug in the treatment of detoxified alcoholics, we performed a 90-day double-blind trial comparing two dosages of acamprosate (1332 mg/day and 1998 mg/day). Results: For all efficacy parameters, acamprosate appeared to be significantly superior to placebo, with a trend towards a better effect at the higher dosage. Furthermore, acamprosate appeared to be extremely safe. Conclusion: This study confirms that acamprosate could be an interesting adjuvant for maintaining abstinence in detoxified alcoholics.
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Cites
The assessment of anxiety states by rating
HAMILTON, M. (1959) · British Journal of Medical Psychology · doi:10.1111/j.2044-8341.1959.tb00467.x · Cited by 11,455
Naltrexone in the Treatment of Alcohol Dependence
Volpicelli, J. R. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820110040006 · Cited by 1,828
Cited by
Jonas, D. E., Amick, H. R., Feltner, C., Bobashev, G., Thomas, K., Wines, R., Kim, M. M., Shanahan, E., Gass, C. E., Rowe, C. J., et al. (2014) · JAMA · doi:10.1001/jama.2014.3628 · Cited by 923
Pharmacological Treatment of Alcohol Dependence: A Review of the Evidence
Garbutt, J. C., West, S. L., Carey, T. S., Lohr, K. N., & Crews, F. T. (1999) · JAMA · doi:10.1001/jama.281.14.1318 · Cited by 444
Gabapentin Treatment for Alcohol Dependence: A Randomized Clinical Trial
Mason, B. J., Quello, S., Goodell, V., Shadan, F., Kyle, M., & Begovic, A. (2014) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.11950 · Cited by 340
Rösner, S., Leucht, S., Lehert, P., & Soyka, M. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881107078308 · Cited by 300
Self-citationRelapse Prevention and Maintaining Abstinence in Older Adults with Alcohol-Use Disorders
Barrick, C., & Connors, G. J. (2002) · Drugs & Aging · doi:10.2165/00002512-200219080-00004 · Cited by 126
Metadata
- Authors
- Pelc, I., Verbanck, P., Bon, O. L., Gavrilovic, M., Lion, K., & Lehert, P.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 1997-07
- Volume
- 171
- Issue
- 1
- Pages
- 73-77
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2099195029
- Cited by
- 184
- References
- 2
- FWCI
- 6.15
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Efficacy and safety of acamprosate in the treatment of detoxified alcohol-dependent patients: A 90-day placebo-controlled dose-finding study. https://app.cochat.ai/papers/10.1192/bjp.171.1.73
- The paper
- Pelc, I., Verbanck, P., Bon, O. L., Gavrilovic, M., Lion, K., & Lehert, P. (1997). Efficacy and safety of acamprosate in the treatment of detoxified alcohol-dependent patients: A 90-day placebo-controlled dose-finding study. British Journal of Psychiatry. https://doi.org/10.1192/bjp.171.1.73
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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