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Cited by 315

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Frontotemporal dementia

Open access
Snowden, Julie S., Neary, David, Mann, David M. A.·2002·British Journal of Psychiatry

Abstract

Background: Frontotemporal dementia accounts for up to 20% of cases of dementia in the presenium, yet remains poorly recognised. Diagnostic criteria have been devised to aid clinical diagnosis. Aims: To provide an overview of clinical and pathological characteristics of frontotemporal dementia and its nosological status. Methods: The review summarises consensus diagnostic criteria for frontotemporal dementia and draws on the authors'clinical experience of 300 frontotemporal dementia cases, and pathological experience of 50 autopsied cases. Results: Frontotemporal dementia is characterised by pronounced changes in affect and personal and social conduct. Some patients also develop motor neuron disease. Mutations in the tau gene account for some but not all familial cases of frontotemporal dementia. Conclusions: Frontotemporal dementia is a focal form of dementia, which is clinically and pathologically distinct from other dementias. It represents an important model for understanding the functions of the frontotemporal lobes.

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Metadata

Authors
Snowden, J. S., Neary, D., & Mann, D. M. A.
Venue
British Journal of Psychiatry
Published
2002-02
Volume
180
Issue
2
Pages
140-143
ISSN
  • 0007-1250 (ISSN-L)
  • 1472-1465
OpenAlex
W4247755733
Cited by
315
References
1
FWCI
5.86
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Frontotemporal dementia. https://app.cochat.ai/papers/10.1192/bjp.180.2.140
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Snowden, J. S., Neary, D., & Mann, D. M. A. (2002). Frontotemporal dementia. British Journal of Psychiatry. https://doi.org/10.1192/bjp.180.2.140

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.