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Cited by 310

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Relapse in schizophrenia: costs, clinical outcomes and quality of life

Open access
Almond, Stephen, Knapp, Martin, Francois, Clement, Toumi, Mondher, Brugha, Traolach·2004·British Journal of Psychiatry

Abstract

Background: Relapse is one of the most costly aspects of schizophrenia. Aims: To compare costs, clinical outcomes and quality of life for patients who experienced relapse in schizophrenia with a control group who did not relapse. Method: Patients were randomly selected from current psychiatric case-loads drawn from urban and suburban areas of Leicester. Differences in costs and outcomes by relapse status in the previous 6 months were examined using parametric and non-parametric tests, and multivariate analysis was used to examine factors associated with relapse and costs. Results: Costs for the patients who relapsed were over four times higher than those for the non-relapse group. There were few statistically significant differences in clinical and quality of life measures by relapse status. Multivariate analyses suggested some significant correlates of relapse and costs. Conclusions: The higher costs associated with relapse will be of interest to policy-makers who face difficult choices concerning new but more expensive treatments for patients with schizophrenia.

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Metadata

Authors
Almond, S., Knapp, M., Francois, C., Toumi, M., & Brugha, T.
Venue
British Journal of Psychiatry
Published
2004-04
Volume
184
Issue
4
Pages
346-351
ISSN
  • 0007-1250 (ISSN-L)
  • 1472-1465
OpenAlex
W2123785744
Cited by
310
References
2
FWCI
5.40
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Relapse in schizophrenia: costs, clinical outcomes and quality of life. https://app.cochat.ai/papers/10.1192/bjp.184.4.346
The paper
Almond, S., Knapp, M., Francois, C., Toumi, M., & Brugha, T. (2004). Relapse in schizophrenia: costs, clinical outcomes and quality of life. British Journal of Psychiatry. https://doi.org/10.1192/bjp.184.4.346

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.