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Effects of treating postnatal depression on mother-infant interaction and child development: Systematic review
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Background: Postnatal depression has detrimental effects on the child's cognitive and emotional development. Aims: To assess the benefits of treating postnatal depression for mother–infant interaction and child development. Method: A systematic search was made of 12 electronic bibliographic databases for randomised controlled trials and controlled clinical trials on treatment of mothers with postnatal depression, where outcomes were assessed in children; findings were assessed. Results: Only eighttrials met the inclusion criteria. Of those included, interventions varied widely but all involved therapies directed at the mother–infant relationship. One study with intensive and prolonged therapy showed cognitive improvement, whereas two others with briefer interventions improved maternal–infant relationships but did not affect the child's cognitive or behavioural development. All five studies assessing only mother–infant relationships showed improvements. Conclusions: Cognitive development in children of depressed mothers, along with better mother–infant relationships, might be improved with sustained interventions. Trials assessing treatments for postnatal depression would benefit from looking more closely at benefits for children as well as mothers, using validated objective measures.
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“Nevertheless, most current PPD treatments treat mothers in isolation, concentrating only on maternal outcomes and neglecting the mother-infant relationship (Nylen et al. 2006; Poobalan et al. 2007).”
From Perinatal Dyadic Psychotherapy for postpartum depression: a randomized controlled pilot trial (2015) · cites this paper as Poobalan et al. 2007
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“Quantitative studies on whether maternal psychotherapy may also improve mother–infant relationships and the infants’ emotional states have been inconclusive (Forman et al., 2007; Poobalan et al., 2007).”
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Enhancing Mother-Child Bonding in the Context of Postpartum Mental Disorders
Weidner, K., Bergunde, L., Frohberg, J., Coenen, A., & Steudte‐Schmiedgen, S. (2023) · Springer eBooks · doi:10.1007/978-3-031-43748-9_6 · Cited by 2
Tryphonopoulos, P. D., McNeil, D. A., Oxford, M. L., Dennis, C., Novick, J., Deane, A. J., Wu, K., Kurbatfinski, S., Griggs, K., & Letourneau, N. L. (2025) · Behavioral Sciences · doi:10.3390/bs15030279 · Cited by 3
“Treatment approaches that solely target maternal depressive symptoms do not necessarily translate to concomitant improvements in the quality of mother–infant interactions or child developmental outcomes (Forman et al., 2007; Poobalan et al., 2007; Richards et al., 2024; Tsivos et al., 2015).”
Jones, A., Golds, L., Duncan, N., Spivacenco, I., Mamaliga, D., Tainsh, R., Ibrahim, R., & MacBeth, A. M. (2025) · PLoS ONE · doi:10.1371/journal.pone.0325245 · Cited by 2
Grussu, P., & Quatraro, R. M. (2014) · Psychology Health & Medicine · doi:10.1080/13548506.2014.947297 · Cited by 3
“Email: pgruss@tin.it © 2014 Taylor & Francis Psychology, Health & Medicine, 2015 Vol. 20, No. 3, 266–273, http://dx.doi.org/10.1080/13548506.2014.947297 development (Poobalan et al., 2007), and the well-being of the entire family (Boath, Pryce, & Cox, 1998; Martell, 1990).”
BackgroundInfluentialLogsdon, M. C., Mittelberg, M., Morrison, D., Robertson, A., Luther, J. F., Wisniewski, S. R., Confer, A. L., Eng, H. F., Sit, D. K. Y., & Wisner, K. L. (2014) · Archives of Psychiatric Nursing · doi:10.1016/j.apnu.2014.08.012 · Cited by 2
“A systematic review of 8 clinical trials demonstrated the effectiveness of interventions directed towards improving the maternal infant relationship in depressed mothers (Poobalan et al., 2007).”
BackgroundJung, E., & Yoo, J. P. (2014) · Asian Social Work and Policy Review · doi:10.1111/aswp.12033 · Cited by 2
Moschner, S. L., Achtergarde, S., & Ramsauer, B. S. (2018) · Praxis der Kinderpsychologie und Kinderpsychiatrie · doi:10.13109/prkk.2018.67.4.351 · Cited by 2
Thompson, L. C., Tanner, J., Breckons, M., Young, N., Ternent, L., Vadiveloo, T., Wilson, P., Wight, D., Marryat, L., McGowan, I., et al. (2024) · Public Health Research · doi:10.3310/kcvl7125 · Cited by 2
Influences in the social worlds of children of mothers with intellectual disability
Collings, S. (2014) · The Sydney eScholarship Repository (The University of Sydney) · doi:10.13140/rg.2.1.4506.2640 · Cited by 2
Daily relationships among maternal rumination, mood and bonding with infant
Tester‐Jones, M., Moberly, N. J., Karl, A., & O’Mahen, H. (2023) · Behaviour Research and Therapy · doi:10.1016/j.brat.2023.104309 · Cited by 1
The gendered trauma trajectories of mothers entering prison
Mitchell, S. (2024) · Probation Journal · doi:10.1177/02645505241269159 · Cited by 1
“Prior research in this area is limited, with most studies coming from the fi eld of health and generally focussing on outcomes for children (Pawlby et al., 2007; Poobalan et al., 2007), rather than links to mothers ’ offending.”
Wagner, G. J., Ghosh‐Dastidar, B., Gwokyalya, V., Faherty, L. J., Beyeza‐Kashesya, J., Nakku, J. E. M., Nabitaka, L. K., Akena, D. H., Nakigudde, J., Ngo, V. K., et al. (2025) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-025-07443-0 · Cited by 1
“Controlled trials of treatment for perinatal depression have shown benefits for maternal functioning and parenting [21–23], but findings have been mixed for effects on child outcomes [24, 25].”
Siu, B. W. M., Chow, H. M.-T., Kwok, S. S.-P., Li, O. L., Koo, M. L., & Poon, P. W. (2011) · Asia-Pacific Psychiatry · doi:10.1111/j.1758-5872.2011.00125.x · Cited by 1
“Poobalan et al. (2007) pointed out in a systematic review that cognitive development in children of depressed mothers, along with better mother–infant relationships, might be improved with sustained interventions.”
BackgroundA Call for Comprehensive Perinatal Psychotherapy Training
Health, B., & Broudy, C. (2017) · Journal of Parent and Family Mental Health · doi:10.7191/parentandfamily.1003 · Cited by 1
Bell, K. J. (2014) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York) · Cited by 1
Metadata
- Authors
- Poobalan, A. S., Aucott, L. S., Ross, L., Smith, W. C. S., Helms, P. J., & Williams, J. H. G.
- Affiliations
- University of Aberdeen (GB)
- Corresponding author
- Poobalan, Amudha S.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2007-11
- Volume
- 191
- Issue
- 5
- Pages
- 378-386
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2026085562
- Cited by
- 238
- References
- 27
- Citations by year
- 2026: 5 · 2025: 11 · 2024: 7 · 2023: 13 · 2022: 7 · 2021: 10 · 2020: 12 · 2019: 15 · 2018: 12 · 2017: 15 · 2016: 17 · 2015: 23 · 2014: 21 · 2013: 17 · 2012: 12
- FWCI
- 8.58
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Development and Preterm Care
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- postpartum depression, mother-infant interaction, child development, child cognitive development, maternal depression treatment, mother-infant relationship, intensive treatment
- MeSH terms
- Adult, Child Development, Cognition, Female, Humans, Infant, Mother-Child Relations, Treatment Outcome, Controlled Clinical Trials as Topic, Depression, Postpartum
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