Cited by 31Attention Deficit Hyperactivity DisorderAutism Spectrum Disorder ResearchDevelopmental and Educational Neuropsychology

Toward operationalizing deficient emotional self-regulation in newly referred adults with ADHD: A receiver operator characteristic curve analysis

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Biederman, Joseph, DiSalvo, Maura, Woodworth, K. Yvonne, Fried, Ronna, Uchida, Mai, Biederman, Itai, Spencer, Thomas J., Surman, Craig +1 more·2020·European Psychiatry

Abstract

Background.: A growing body of research suggests that deficient emotional self-regulation (DESR) is common and morbid among attention-deficit/hyperactivity disorder (ADHD) patients. The main aim of the present study was to assess whether high and low levels of DESR in adult ADHD patients can be operationalized and whether they are clinically useful. Methods.: A total of 441 newly referred 18- to 55-year-old adults of both sexes with Diagnostic and Statistical Manual of Mental Disorders: Fifth Edition (DSM-5) ADHD completed self-reported rating scales. We operationalized DESR using items from the Barkley Current Behavior Scale. We used receiver operator characteristic (ROC) curves to identify the optimal cut-off on the Barkley Emotional Dysregulation (ED) Scale to categorize patients as having high- versus low-level DESR and compared demographic and clinical characteristics between the groups. Results.: We averaged the optimal Barkley ED Scale cut-points from the ROC curve analyses across all subscales and categorized ADHD patients as having high- (N = 191) or low-level (N = 250) DESR (total Barkley ED Scale score ≥8 or <8, respectively). Those with high-level DESR had significantly more severe symptoms of ADHD, executive dysfunction, autistic traits, levels of psychopathology, and worse quality of life compared with those with low-level DESR. There were no major differences in outcomes among medicated and unmedicated patients. Conclusions.: High levels of DESR are common in adults with ADHD and when present represent a burdensome source of added morbidity and disability worthy of further clinical and scientific attention.

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Authors
Biederman, J., DiSalvo, M., Woodworth, K. Y., Fried, R., Uchida, M., Biederman, I., Spencer, T. J., Surman, C., & Faraone, S. V.
Affiliations
  • Harvard University (US)
  • Massachusetts General Hospital (US)
  • SUNY Upstate Medical University (US)
Corresponding author
Biederman, Joseph
Venue
European Psychiatry
Published
2020
Volume
63
Issue
1
Pages
e21-e21
ISSN
  • 0924-9338 (ISSN-L)
  • 1778-3585
OpenAlex
W3008554509
Cited by
31
References
19
Citations by year
2026: 4 · 2025: 2 · 2024: 7 · 2023: 5 · 2022: 5 · 2021: 4 · 2020: 4
FWCI
3.28
Type
journal article
Language
en
Open access
Locations
  • European Psychiatry (publishedVersion, cc-by-nc-sa)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
Keywords
adult ADHD, emotional dysregulation, executive dysfunction, autistic traits, psychopathology, quality of life, ADHD symptom severity, ADHD medication
MeSH terms
Self-Control, Emotional Regulation, Adolescent, Adult, Attention Deficit Disorder with Hyperactivity, Female, Humans, Male, Middle Aged, Quality of Life, Referral and Consultation, Research Design, ROC Curve, Young Adult, Self Report

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