Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies

Shinohara, Mitsuru, Tachibana, Masaya, Kanekiyo, Takahisa, Bu, Guojun·2017·Journal of Lipid Research
DOI 10.1194/jlr.r075796

Cited by (309)

Items 201–300 of 309

  1. Regulation of the Blood–Brain Barrier in Health and Disease
    Cara Coleen Rada, Kanako Yuki, Jie Ding, Calvin Jay Kuo · 2023 · Cold Spring Harbor Perspectives in Medicine
  2. Cell signaling pathways discovery from multi-modal data
    He, Changhan, Simpson, Claire, Cossentino, Ian, Zhang, Bin, Tkachev, Sasha, Eddins, Devon J., Kosters, Astrid, Yang, Junkai, Sheth, Shivani, Levy, Tyler et al. · 2025
  3. Proteostasis disruption and lipid dyshomeostasis in neurodegeneration: exploring common druggable targets across sporadic and monogenic disorders
    Priscila Pereira Sena, Lea Friedrich, Alcibiades E. Villarreal, Florian Fath, Liubovi Sopco, Mar Hernández‐Guillamón, Maria Luiza Saraiva Pereira, Gabrielle B. Britton, Jonasz Jeremiasz Weber, Thorsten Schmidt · 2025 · Frontiers in Molecular Neuroscience
  4. Pregnane X receptor activation regulate amyloid transport to improve cognition functions in Alzheimer's disease
    Tiancheng Gu, Sherie Ma, Wei Liu, Laiyou Wang · 2025 · European Journal of Pharmacology
  5. Brain capillary endothelial-like cells show altered barrier functionality and reduced transport of amyloid β in late-onset Alzheimer disease
    Carla Hartmann, Undine Haferkamp, Antje Appelt‐Menzel, Janica Barenberg, Andreas Brachner, Toni Ehrhard, Julia Silvia Feldhaus, Anna Gerhartl, Thomas Hollemann, Linda Anna Michelle Kulka et al. · 2026 · Fluids and Barriers of the CNS
  6. Neuroprotective Role of Pioglitazone Against LPS-Induced Neuroinflammation in Wistar Rats, Targeting Superoxide Dismutase, Lipid Peroxidation and Cognitive Changes
    Vandana Blossom, Sheetal Dinkar Ullal, Rajalakshmi Rai, Anupama Hegde, Sharada Rai, Anita Sherly A · 2026 · Oxygen
  7. New aspects of a small GTPase RAB35 in brain development and function
    Ikuko Maejima, Ken Sato · 2024 · Neural Regeneration Research
  8. NMT2 alleviates depression-like behavior in a rat model of chronic unpredictable stress: An integrated proteomic and phosphoproteomic analysis
    Ye Sun, Danmei Zhao, Qiuyan Song, Ting Cong, Liya Li, Haibo Wu, Zhaoyang Xiao · 2024 · Journal of Psychiatric Research
  9. Aerobic Exercise Ameliorates Alzheimer’s Disease-Like Pathology by Regulating Hepatic Phagocytosis of Aβ
    Qing Wang, Feng-Rui Hu, Xingchun Gou, Shan Wang, Naichun Ji · 2025 · Frontiers in Bioscience-Landmark
  10. Multimodal Imaging of Blood–Brain Barrier Dysfunction in Parkinson's Disease: From Pathological Mechanisms to Therapeutic Opportunities
    Zhihong Lu, Haolin Yin, Pan Xiang, Xuan Yi, Xiaohe Tian, Qiyong Gong · 2025 · European Journal of Neuroscience
  11. Unappreciated role of low‐density lipoprotein receptor‐related protein 1 in pancreatic β cells: Multiple roles of low‐density lipoprotein receptor‐related protein 1 in glucose and lipid metabolism
    Hirotaka Watada · 2018 · Journal of Diabetes Investigation
  12. A Comprehensive Computational Perspective in Drug Discovery for Alzheimer's Disease
    Manikandan Selvaraj, Karthik Sadasivam, Muralidharan Jothimani, Karthikeyan Muthusamy · 2022 · Combinatorial Chemistry & High Throughput Screening
  13. Exome-wide analysis reveals role of LRP1 and additional novel loci in cognition
    Shreya Chakraborty, Bratati Kahali · 2023 · Human Genetics and Genomics Advances
  14. Codon Pattern and Context Analysis in Genes Triggering Alzheimer’s Disease and Latent Tau Protein Aggregation Post-Anesthesia Exhibited Unique Molecular Patterns Associated with Functional Aspects
    Liyuan Jiao, Ziye Jing, Wenjie Zhang, Xuesen Su, Hualei Yan, Shouyuan Tian · 2024 · Journal of Alzheimer s Disease
  15. Immuno-Nanotherapeutics Approach for the Treatment and Management of Alzheimer’s Disease
    Deena M. Bukhary · 2024 · International Journal of Pharmacology
  16. Dysregulated glycerophospholipid metabolism in amygdala may mediate favipiravir-induced anxiety-like behaviors in mice
    Yuzhou Xiao, Chunqi Liu, Xiaojie Wang, Hongchun Li, Liang Wang, Kun Gou, Xingchen Liu, Xinqi Guan, Xia Zhou, Xiumei He et al. · 2025 · Frontiers in Pharmacology
  17. Multiomics reveal biomolecular shifts and ER stress in sleep-restricted women affecting NSC functions
    Vikas Malik, Xin Huang, Hongwei Zhou, Rebecca Bojar, Rajesh Kumar Soni, Donald W. Landry, Sanja Jelić, Jianlong Wang · 2025 · iScience
  18. The effects of Honokiol on the liver of Alzheimer's disease mice by upregulating SIRT3
    Hao Wang, Jun Liu, Yuanruhua Tian, Feiqi Zhu, Haitao Li · 2025 · Journal of Alzheimer s Disease
  19. Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone
    Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth Anthony Wilson, Hazel Baker, Mikayla Hady et al. · 2026 · Advanced Science
  20. Decoding the role of LRP1 in cancers: From molecular mechanisms to therapeutic opportunities
    Dan Zou, Jike Hu, Yunpeng Wang, Puyi He, L. Gao, Huanhuan Ma, Ying Yan, YIFAN LI, Kai Wang, Weiyi Chen et al. · 2026 · Critical Reviews in Oncology/Hematology
  21. Modulating LRP1 Pathways in Alzheimer’s Disease: Mechanistic Insights and Emerging Therapies
    Tehreem Mushtaq, Huma Hameed, Mahtab Ahmad Khan, Urwa Tariq, Anam Hameed, Muhammad Zaman · 2026 · Molecular Neurobiology
  22. Alzheimer’s disease DNA methylation index (AD-DMI) and its association with late-life cognitive function
    Nwanyieze Ngozi Jiakponnah, Ifechukwude Joachim Biose, Tracy Fischer, Katie E. Cherry, James Cronin, S. Michal Jazwinski, Sangkyu Kim · 2026 · npj Dementia
  23. TTC17 is an endoplasmic reticulum resident TPR-containing adaptor protein
    Nathan P. Canniff, Jill B. Graham, Kevin P. Guay, Daniel A. Lubicki, Stephen J. Eyles, Jennifer N. Rauch, Daniel N. Hebert · 2023 · Journal of Biological Chemistry
  24. Apolipoprotein E (APOE) Isoforms and Neurobiology of Sporadic Alzheimer’s Disease
    Anita Mollica, Giuseppe Berardino, Antonello Bellomo, Mario Altamura, Francesco Panza, Madia Lozupone · 2024 · Springer eBooks
  25. Identification of TMED10 as A Regulator for Neuronal Exocytosis of Amyloid Beta 42
    Peixin Meng, Longze Sha, Xiaolin Yu, Yanbing Wang, Erning Zhang, Kexin Meng, Bingnan Li, Qin Zhao, Qi Xu · 2025 · Neuroscience Bulletin
  26. Involvement of a Na+-coupled Oligopeptide Transport System for β-amyloid Peptide (Aβ1–42) in Brain Cells
    Kei Higuchi, Toshihiro Sato, Yangzom Doma Bhutia, Vadivel Ganapathy · 2020 · Pharmaceutical Research
  27. Role of caspases, apoptosis and additional factors in pathology of Alzheimer's disease
    Anil Gupta · 2021 · Elsevier eBooks
  28. Articulating target-mining techniques to disinter Alzheimer's specific targets for drug repurposing
    Hema Sree G N S, V. Lakshmi Prasanna Marise, Saraswathy Ganesan Rajalekshmi, Raghunadha Reddy Burri, T. P. Krishna Murthy · 2022 · Computer Methods and Programs in Biomedicine
  29. Unraveling the intercellular communication disruption and key pathways in Alzheimer's disease: An integrative study of single-nucleus transcriptomes and genetic association
    Andi Liu, Brisa Simões Fernandes, Citu Citu, Zhongming Zhao · 2023 · Research Square
  30. MMCCI: multimodal integrative analysis of single-cell and spatial cell-type communications to uncover overarching and condition-specific ligand-receptor interaction pathways
    Levi Hockey, Onkar Mulay, Zherui Xiong, Samuel X. Tan, Kiarash Khosrotehrani, Christian Maximilian Nefzger, Quan Hoang Nguyen · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  31. Red-light radiation: does it enhance memory by increasing hippocampal LRP-1 and TRPA-1 genes expression?
    Saereh Haghjoo, Mojtaba Hedayati, Mohammad Rostampour, Behrooz Khakpour-Taleghani · 2022 · International Journal of Radiation Biology
  32. LRP1 Shedding in Ricin-Induced Lung Injury: A Cell-Specific Response to Toxin Exposure
    Anita Sapoznikov, Yentl Evgy, Moshe Aftalion, Reut Falach · 2025 · International Journal of Molecular Sciences
  33. Glycogen synthase kinase-3 activation and dysregulation of amyloid transport receptors expression and shedding in HIV-induced Alzheimer’s disease-like pathology: modulatory effects of CCR5 antagonists
    Biju Bhargavan, Narendran Annadurai, Georgette D. Kanmogne · 2025 · Acta Neuropathologica Communications
  34. Targeting the astrocytic metabolic cascade in Alzheimer’s disease: mechanisms, challenges and opportunities
    Huawen Cao, Junyi Liang, Xiaohong Dong, Zhiqi Xia, Xiaoting Luo, Bin Liu · 2026 · Frontiers in Aging Neuroscience
  35. Revisiting cirrhosis-related parkinsonism: a comprehensive review
    Luis E. Fernández-Garza, Luis Andrés González Torres, Ingrid E. Estrada-Bellmann, Carlos Alejandro Cortéz-Hernández, Valeria A. Fernández-Garza, Renata P. Nomura-Quiroz, Alexandro Navarrete-Rodríguez · 2026 · Metabolic Brain Disease
  36. Integrated imaging and molecular profiling reveals APOE4-associated neurovascular and glial disruptions in young adult mice
    Yi Guan, Chia Hsin Cheng, Sonal Khanna, Catalina Fader, Yolanda Ohene, Jack A. Wells, Bang‐Bon Koo · 2026 · Journal of Neuroinflammation
  37. ApoE: A Risk Factor for Dementia
    Humira Jeelani, Jahangir Nabi, Yasmeena Akhter, Nahida Tabasum, Dil Afroze, Faheem Hyder Pottoo, Fasil Ali · 2022 · Springer eBooks
  38. Synthesis and PET Imaging Biodistribution Studies of Radiolabeled Iododiflunisal, a Transthyretin Tetramer Stabilizer, Candidate Drug for Alzheimer’s Disease
    Sameer M. Joshi, Thomas C. Wilson, Zibo Li, Sean Preshlock, Vanessa Gómez‐Vallejo, Véronique Gouverneur, Jordi Llop, Gemma Arsequell · 2024 · Molecules
  39. Nanoparticles beyond the blood-brain barrier for glioblastoma
    Lynn Jena, Nicholas Dunne, Helen O. McCarthy · 2021 · Elsevier eBooks
  40. The Role of Polyphenols in the Treatment of Alzheimer's Disease: Narrative Review
    Reem Halim Alattiya, Farah Khalid Tarish, Lina Loai Hashim, Saad Abdulrahman Hussain · 2021 · Al-Rafidain Journal of Medical Sciences
  41. Pathological Characteristics of Malformations of Cortical Development in Golden Syrian Hamsters with LDLR Deficiency
    Yun Bai, Xiaohui Dong, Mingzhao Li, Naiheng Hei, Ge Chen, Mei Li, Pengfei Yin, Lianshan Zhang · 2021 · Journal of Neuropathology & Experimental Neurology
  42. BMP9 ameliorates amyloid pathology by promoting low-density lipoprotein receptor-related protein 1 expression in APP/PS1 transgenic mice
    Lu Xiong, Zigao Wang · 2023 · Neuroscience Letters
  43. LRPs in Bone Homeostasis and Disease
    Mei Wan · 2019 · Elsevier eBooks
  44. Immune Metabolism in Functional Aspects of the Brain
    Elisa Gonzalez Cuevas, Nitya G. Chakraborty · 2019 · American Journal of Immunology
  45. Apolipoprotein E: Cholesterol metabolism and Alzheimer’s pathology
    Theresa Pohlkamp · 2020 · e-Neuroforum
  46. LRP-1 Commands Two Parallel Signalling Mechanisms to Support Constitutive Tumour Cell Motility in the Absence of Blood Supply
    Cheng Chang, Xin Tang, Daniel Mosallaei, Mei Chen, David T. Woodley, Axel H. Schönthal, Wei Li · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  47. Revisión bibliográfica de los avances más recientes en la comprensión etiológica de la enfermedad de Alzheimer
    Uziel Amit Téllez Ramírez, María Eugenia Medina, Ana Paulina Reyes Ruiz, María de los Ángeles Silva Borja, Oscar Uriel Díaz Ricoy · 2021 · Lux Médica
  48. Faculty Opinions recommendation of LRP1 is a master regulator of tau uptake and spread.
    Giampietro Schiavo, Edoardo Moretto · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  49. Alzheimer’s disease as a syndrome of overloaded amyloidic synaptic tagging in memory networks
    Niall Murphy · 2021 · OSF Preprints (OSF Preprints)
  50. Interaction between oxidative stress and epigenetics decreases the low density lipoprotein receptor related protein 1 (LRP1) expression on the blood-brain barrier (BBB) in Alzheimer’s disease
    Nikola Barić · 2022 · Rad Hrvatske akademije znanosti i umjetnosti Medicinske znanosti
  51. Impact of isoform and Cys-thiol modifications of apolipoprotein E on the LRP1-mediated metabolism of triglyceride-rich lipoproteins
    Hiroto Matsuura, Shogo Akahane, Takahiro Kaido, Tomu Kamijo, Kenta Sakamoto, Kazuyoshi Yamauchi · 2023 · Research Square
  52. WITHDRAWN: Helicobacter Pylori-Vacuolating Cytotoxin A Inducing Neurotoxic Neuroinflammation in Human Stomach-Brain Axis
    Van Thi Ai Tran, Niloofar Etemadi, Minh Tran, Jungmi Lee, Han Seok Ko, Dong‐Gyu Jo, Luke P. Lee, Hansang Cho · 2023 · Research Square
  53. Expression of Anti-Neurodegeneration Genes in Mutant Caenorhabditis elegans Using CRISPR-Cas9 Improves Behavior Associated With Alzheimer’s Disease
    Roshni Mishra, Leya Joykutty, Kepa Oyarbide · 2019 · Journal of Emerging Investigators
  54. Modulation of Alzheimer’s Disease Brain Pathology in Mice by Gut Bacterial Deletion: The Role of Il-17a and Microglial MyD88
    Wenlin Hao, Qinghua Luo, Inge Tomic, Wenqiang Quan, Tobias Hartmann, Michael Dieter Menger, Klaus C Fassbender, Yang Liu · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  55. A Connectivity between LRP-1 and Alzheimer’s Disease: Modulating the Transport and Clearance of Tau and Aβ Clearance from the Brain to the Liver
    Lawrence Kevin Duffy · 2023 · Advances in Clinical Toxicology
  56. Analysis of transporter activity in an Alzheimer’s disease blood-brain barrier cell model
    J. Chaves · 2024 · Queensland University of Technology
  57. Celastrol attenuates Alzheimer's disease-mediated learning and memory impairment by inhibiting endoplasmic reticulum stress-induced inflammation and oxidative stress
    Fanfan Cao, Limin Xu, Xiaoxue He, Yongbin Chi, Ying Wang, Denghai Zhang, Qiuyun Liu · 2024 · Archives of Medical Science
  58. WITHDRAWN: Helicobacter Pylori-Vacuolating Cytotoxin A Inducing Neurotoxic Neuroinflammation in Human Stomach-Brain Axis
    Van Thi Ai Tran, Niloofar Etemadi, Minh Tran, Jungmi Lee, Han Seok Ko, Dong‐Gyu Jo, Luke P. Lee, Hansang Cho · 2025 · Research Square
  59. Protective Effect of an Sco-Spondin Derived Hexapeptide Against Beta-Amyloid Aggregates
    Zsolt Datki, Rita Sinka, Brian J. Dingmann, Bence Gálik, Antal Szabo, Zita Galik-Olah, Gábor K. Tóth, Zsolt Bozsó · 2025 · SSRN Electronic Journal
  60. ApoE Receptors, Molecular Processes, and Cellular Signaling Pathways
    Anja Jaeschke, David Y. Hui · 2025 · Springer eBooks
  61. Role of Hepatic Lipoprotein Receptor-related Protein 1 (LRP-1) on Amyloid Beta Pathology in a Mouse Model of Amyloidosis
    Urvashi R. Panchal · 2025 · Chapman University Digital Commons (Chapman University)
  62. Protective Effect of a Hexapeptide Derived from Rotifer-Specific SCO-Spondin Against Beta-Amyloid Toxicity
    Zsolt Datki, Rita Sinka, Brian J. Dingmann, Bence Gálik, Antal Szabo, Zita Galik-Olah, Gábor K. Tóth, Zsolt Bozsó · 2025 · International Journal of Molecular Sciences
  63. A computational analysis of the glycoprotein lipoprotein receptor-related protein 1 structure and the role of glycans as quaternary glue
    Gian Marco Tuveri, Marco Basile, Silvia Acosta‐Gutiérrez, Marius Kausas, Sílvia Pujals, Xiaohe Tian, Giancarlo Franzese, Lorena Ruiz‐Pérez, Giuseppe Battaglia · 2026 · Bioinformatics
  64. Inhibition of Acyl-CoA: Cholesterol Acyltransferase 1 Promotes Shedding of Soluble TREM2 and LRP1-Dependent Phagocytosis of Amyloid β Protein in Microglia
    Hovde, Moriah J., Maaser-Hecker, Anna, Tanzi, Rudolph E. · 2025
  65. Apolipoprotein E (APOE) Isoforms and Neurobiology of Sporadic Alzheimer’s Disease
    Anita Mollica, Giuseppe Berardino, Antonello Bellomo, Mario Altamura, Francesco Panza, Madia Lozupone · 2025 · Springer eBooks
  66. Exploration of the potential role of plasma lipoprotein molecules in late-onset Alzheimer's disease among the Chinese population
    Shitao Wang, Guoshuai Luo, Qingqing Zhao, Shangrong Zhang, Zongyou Li, Jinghong Lu, Fei Wang, Daliang Sun, Hui Min Xu · 2025 · Journal of Alzheimer s Disease Reports
  67. ABC Transporters, APOE, CYP46A1, and LRP1 Gene Polymorphisms as Markers of Dementia Development in Patients with Hyperlipidemia
    Marta Machowska, Jerzy Leszek, Maja Rączy-Krzemianowska, Beata Tomasiewicz, Magdalena Hurkacz, Małgorzata Rąpała, Janusz Piechota, Krystyna Głowacka, Anna Wiela−Hojeńska · 2025 · International Journal of Molecular Sciences
  68. Additional file 3 of Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice
    Shen, Jiacheng, Li Wu, Shi, Xiaoying, Chen, Gang, Tingwei Liu, Xu, Fangfang, Xu, Xiaocui, Xiaochen Kou, Zhao, Yanhong, Wang, Hong et al. · 2024 · Figshare
  69. Additional file 4 of Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice
    Shen, Jiacheng, Li Wu, Shi, Xiaoying, Chen, Gang, Tingwei Liu, Xu, Fangfang, Xu, Xiaocui, Xiaochen Kou, Yanhong Zhao, Wang, Hong et al. · 2024 · Figshare
  70. Additional file 1 of Cortical lipid metabolic pathway alteration of early Alzheimer’s disease and candidate drugs screen
    Wang, Linshuang, Fengxue Qu, Yu, Xueyun, Sixia Yang, Zhao, Binbin, Yaojing Chen, Li, Pengbo, Zhang, Zhanjun, Zhang, Junying, Xuejie Han et al. · 2024 · Figshare
  71. Additional file 5 of Unraveling the intercellular communication disruption and key pathways in Alzheimer’s disease: an integrative study of single-nucleus transcriptomes and genetic association
    Liu, Andi, Fernandes, Brisa S., Citu Citu, Zhao, Zhongming · 2024 · Figshare
  72. Additional file 4 of Unraveling the intercellular communication disruption and key pathways in Alzheimer’s disease: an integrative study of single-nucleus transcriptomes and genetic association
    Liu, Andi, Brisa Simões Fernandes, Citu Citu, Zhao, Zhongming · 2024 · Figshare
  73. Additional file 7 of Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice
    Shen, Jiacheng, Li Wu, Shi, Xiaoying, Chen, Gang, Tingwei Liu, Xu, Fangfang, Xu, Xiaocui, Xiaochen Kou, Zhao, Yanhong, Wang, Hong et al. · 2024 · Figshare
  74. Additional file 6 of Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice
    Shen, Jiacheng, Li Wu, Shi, Xiaoying, Chen, Gang, Tingwei Liu, Xu, Fangfang, Xu, Xiaocui, Xiaochen Kou, Yanhong Zhao, Wang, Hong et al. · 2024 · Figshare
  75. Additional file 2 of Unraveling the intercellular communication disruption and key pathways in Alzheimer’s disease: an integrative study of single-nucleus transcriptomes and genetic association
    Liu, Andi, Brisa Simões Fernandes, Citu Citu, Zhao, Zhongming · 2024 · Figshare
  76. Additional file 1 of Unraveling the intercellular communication disruption and key pathways in Alzheimer’s disease: an integrative study of single-nucleus transcriptomes and genetic association
    Liu, Andi, Fernandes, Brisa S., Citu Citu, Zhao, Zhongming · 2024 · Figshare
  77. Additional file 2 of Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice
    Shen, Jiacheng, Li Wu, Shi, Xiaoying, Chen, Gang, Tingwei Liu, Xu, Fangfang, Xu, Xiaocui, Xiaochen Kou, Zhao, Yanhong, Wang, Hong et al. · 2024 · Figshare
  78. Additional file 1 of Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice
    Shen, Jiacheng, Li Wu, Shi, Xiaoying, Chen, Gang, Tingwei Liu, Xu, Fangfang, Xu, Xiaocui, Xiaochen Kou, Zhao, Yanhong, Wang, Hong et al. · 2024 · Figshare
  79. Additional file 7 of Unraveling the intercellular communication disruption and key pathways in Alzheimer’s disease: an integrative study of single-nucleus transcriptomes and genetic association
    Liu, Andi, Fernandes, Brisa S., Citu Citu, Zhao, Zhongming · 2024 · Figshare
  80. Additional file 6 of Unraveling the intercellular communication disruption and key pathways in Alzheimer’s disease: an integrative study of single-nucleus transcriptomes and genetic association
    Liu, Andi, Brisa Simões Fernandes, Citu Citu, Zhao, Zhongming · 2024 · Figshare
  81. Additional file 5 of Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice
    Shen, Jiacheng, Li Wu, Shi, Xiaoying, Chen, Gang, Tingwei Liu, Xu, Fangfang, Xu, Xiaocui, Xiaochen Kou, Yanhong Zhao, Wang, Hong et al. · 2024 · Figshare
  82. Additional file 3 of Unraveling the intercellular communication disruption and key pathways in Alzheimer’s disease: an integrative study of single-nucleus transcriptomes and genetic association
    Liu, Andi, Fernandes, Brisa S., Citu Citu, Zhao, Zhongming · 2024 · Figshare
  83. In Vitro Study on the Distribution of Aβ in Sandwich Cultured Human Immortalized Liver Cells
    湉柽 辜 · 2025 · Bioprocess
  84. Role of apolipoprotein E4 in alzheimer’s disease pathogenesis and emerging therapeutic strategies
    Sribha Natarajan, Sundara Dhakshinamurthy Saraswathy · 2025 · Metabolic Brain Disease
  85. Serum Soluble Low-Density Lipoprotein Receptor-Related Protein 1 (sLRP1) is Negatively Associated With Functional Outcome Improvement From 3 to 12 Months After Acute Ischemic Stroke
    Mingxi Chen, Keying Wu, Huan Wang, Yuyi Zhu, Chen Yaqi, Ting Cui, Zhen Liu, Xinyi Leng, Zilong Hao, Deren Wang · 2025 · Neurorehabilitation and neural repair
  86. Decoding the effects of Bexarotene treatment on brain of AD‐like model mice: single‐cell transcriptomics and chromatin accessibility analysis
    Yi Lu, Xuebao Wang, Carolina Saibro Girardi, Nicholas Francis Fitz, Radosveta Koldamova, Iliya Lefterov · 2025 · Alzheimer s & Dementia
  87. Systemic Amyloid-β Metabolism in Alzheimer’s Disease
    Fan Dong-yu, Jun Wang, Ben J. Gu, Colin Louis Masters, Yan‐Jiang Wang · 2026 · Springer eBooks
  88. The Proteome of Human Amyloid Beta Oligomers
    Bettina Kass, Gereon Poschmann, Fatih Demir, Pitter F. Huesgen, K. Stühler, Janine Kutzsche, Dieter Willbold · 2026 · Biochemistry
  89. Mechanistic modeling of amyloid dynamics relating to Alzheimer's disease progression
    Andrzej J. Przekwas, Carly Norris, Harsha Teja Garimella · 2026 · Frontiers in Aging Neuroscience
  90. Etude de l'interface fonctionnelle LRP-1/intégrine beta1 dans le cadre de la progression tumorale.
    Louis Thérêt · 2017 · theses.fr (ABES)
  91. MT5-MMP promotes neuroinflammation, pathogenic processing of amyloid precursor protein and synaptic dysfunction at early stages in an Alzheimer's disease model
    Dominika Piłat · 2021 · theses.fr (ABES)
  92. Rôle de LRP-1 dans la prolifération des cellules issues de cancer du côlon en matrice tridimensionnelle de collagène de type I
    C. Le · 2020 · theses.fr (ABES)
  93. Rôle du récepteur LRP-1 dans la croissance tumorale et l’angiogenèse associée dans un modèle de cancer mammaire triple négatif
    Océane Campion · 2021 · theses.fr (ABES)
  94. The Use of Localized Proteomics to Understand the Pathogenesis of Alzheimer's Disease
    Geoffrey Pires · 2021 · theses.fr (ABES)
  95. Low-density lipoprotein receptor-related protein 1 as a therapeutic target in acute myocardial infarction: From mechanisms to clinical translation
    Michele Marchetta, Rocio I Lopez, Nicola Potere, Lavie Ngo, Jeff Saucerman, Stefano A Toldo, Antonio Abbate · 2026 · Journal of Pharmacology and Experimental Therapeutics
  96. LRP‐1 as Target of Broad‐Specific Antivirals: Benefits, Risks and Challenges
    Daniela Maldonado Bauzá, Luis Gabriel González‐Lodeiro, Wen Li, Vivian Huerta · 2026 · Reviews in Medical Virology
  97. Glycosylation modulation as a therapeutic strategy for neuroinflammatory disorders: The potential of Tanshinone IIA
    Yahui Li, Kunfeng Duan, Guangyuan Liu, Jingwen Yan, Qian Wang, Yuyu Zhang, Yuran Wang, Bowen Guo, P F Zhang, Wei Zhang et al. · 2026 · iScience
  98. Circulatory pro‐CTSD binds brain endothelial LRP1 to trigger its lysosomal degradation leading to amyloid beta clearance deficit in Alzheimer's disease mice
    Zhi-Jun Li, Zhao Yang, Dan Zhao, Yihua Qiu, Wen‐Yu Wan, Zeng-Kang Huang, Li Tian, Rui‐Qun Qi, Hongguang Liu, Yuehua Chen et al. · 2026 · Alzheimer s & Dementia
  99. Brain shuttle target expression levels vary by individual, not by brain region, disease, age, or sex
    Ana Raquel Santa-Maria, Sanjid Shahriar, Vasanth Chandrasekhar, Emma Luteijn, Robin Horber, Samuel Hornstein, Sasha L. Tkachev, Tyler M. Levy, Ivan V. Gregoretti, Claire M. Simpson et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  100. Neurovascular coupling and energy substrate delivery in Alzheimer’s disease
    Shivam Malviya, Debasmita Saha, Anagha Kamble, Divya Ramesh Singh, Sivaraj Mohana Sundaram, Vasudharani Devanathan · 2026 · International review of neurobiology