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Prostanoids in health and disease
Open accessAbstract
The prostanoids are a family of lipid mediators generated by the action of cyclooxygenase on a 20-carbon unsaturated fatty acid, arachidonic acid. Prostanoids are generated widely in response to diverse stimuli and, acting in a paracrine or autocrine manner, play important roles in normal physiology and disease. This review summarizes the current knowledge on prostanoid generation and the roles of individual mediators, their biosynthetic pathways, and their receptors in health and disease.
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Metadata
- Authors
- Smyth, E. M., Grosser, T., Wang, M., Yu, Y., & FitzGerald, G. A.
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 2009-04
- Volume
- 50
- Pages
- S423-S428
- ISSN
- 0022-2275 (ISSN-L)
- OpenAlex
- W2162392926
- Cited by
- 543
- References
- 1
- FWCI
- 13.45
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Smyth, E. M., Grosser, T., Wang, M., Yu, Y., & FitzGerald, G. A. (2009). Prostanoids in health and disease. Journal of Lipid Research. https://doi.org/10.1194/jlr.r800094-jlr200
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
