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Enhancing Hepatic MBOAT7 Expression in Mice With Nonalcoholic Steatohepatitis

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Phospholipid Acyltransferases: Characterization and Involvement of the Enzymes in Metabolic and Cancer Diseases

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The Intersection of Genetic Factors, Aberrant Nutrient Metabolism and Oxidative Stress in the Progression of Cardiometabolic Disease

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Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury

Varadharajan, V., Ramachandiran, I., Massey, W. J., Jain, R., Banerjee, R., Horak, A. J., McMullen, M. R., Huang, E., Bellar, A., Lorkowski, S. W., et al. (2024) · eLife · doi:10.7554/elife.92243.3 · Cited by 12 · see citing works

The Pivotal Role of the Membrane-Bound O-Acyltransferase Domain Containing 7 in Non-Alcoholic Fatty Liver Disease

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Novel insights into metabolic‐associated steatotic liver disease preclinical models

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Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury

Varadharajan, V., Ramachandiran, I., Massey, W. J., Jain, R., Banerjee, R., Horak, A. J., McMullen, M. R., Huang, E., Bellar, A., Lorkowski, S. W., et al. (2023) · eLife · doi:10.7554/elife.92243 · Cited by 9 · see citing works

Genetic variants associated with steatohepatitis and liver fibrosis in HIV-infected patients with NAFLD

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Genetic Markers Predisposing to Nonalcoholic Steatohepatitis

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Protective Effect of Modified Suanmei-Tang on Metabolic-Associated Fatty Liver Disease: An Integrated Strategy of Network Pharmacology, Metabolomics, and Transcriptomics

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Recent advances in MASLD genetics: Insights into disease mechanisms and the next frontiers in clinical application

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Targeting the LPI / GPR55 Axis in MAFLD and MASH : Novel Insights, Therapeutic Strategies and Future Directions

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Non-alcoholic fatty liver disease establishment and progression: genetics and epigenetics as relevant modulators of the pathology

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Adipocyte phosphatidylinositol biosynthesis via the Lands cycle protects against insulin resistance

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Understanding the underlying molecular pathways by which Mboat7/Lpiat1 depletion induces hepatic steatosis

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Integration of Metabolomics, Lipidomics, and Machine Learning for Developing a Biomarker Panel to Distinguish the Severity of Metabolic‐Associated Fatty Liver Disease

Hui, Y., Qu, J., Yang, J., Zhang, H., Chen, L., Miao, N., Zhang, Q., Xu, H., Li, Y., & Li, Q. (2025) · Biomedical Chromatography · doi:10.1002/bmc.70142 · Cited by 2 · see citing works

Genetic risk of steatotic liver disease: Pathogenesis, prognosis, and implications for treatment

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Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver InjuryPreprint

Varadharajan, V., Ramachandiran, I., Massey, W. J., Jain, R., Banerjee, R., Horak, A. J., McMullen, M. R., Huang, E., Bellar, A., Lorkowski, S. W., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.26.559533 · Cited by 2 · see citing works

Genetic Diversity Estimation and Genome-Wide Selective Sweep Analysis of the Bazhou Yak

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Hepatic Lipoprotein Production, Cardiometabolic Phenotypes, and Subtypes of Steatotic Liver Disease

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Molecular Mechanisms by Which Polyunsaturated Fatty Acids Suppress the Pathogenesis and Progression of NAFLD

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Enhancing Hepatic MBOAT7 Expression Does Not Improve Nonalcoholic Steatohepatitis in MicePreprint

Sharpe, M. C., Pyles, K. D., Hallcox, T., Kamm, D. R., Piechowski, M., Fisk, B. A., Albert, C. J., Carpenter, D. H., Ulmasov, B., Ford, D. A., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.03.24.485677

Membrane Bound O-Acyltransferase 7 (MBOAT7)-Driven Lysophosphatidylinositol (LPI) Acylation in Adipocytes Contributes to Systemic Glucose HomeostasisPreprint

Massey, W. J., Varadharajan, V., Banerjee, R., Brown, A. L., Horak, A. J., Hohe, R. C., Chan, E. R., Pan, C., Zhang, R., Allende, D. S., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.19.492632

Cell and molecular basis for maintenance of cholesterol homeostasis

Smith, T. A., & DeBose‐Boyd, R. A. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95582-9.00005-x

Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver InjuryPreprint

Varadharajan, V., Ramachandiran, I., Massey, W. J., Jain, R., Banerjee, R., Horak, A. J., McMullen, M. R., Huang, E., Bellar, A., Lorkowski, S. W., et al. (2023) · eLife · doi:10.7554/elife.92243.1

Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver InjuryPreprint

Varadharajan, V., Ramachandiran, I., Massey, W. J., Jain, R., Banerjee, R., Horak, A. J., McMullen, M. R., Huang, E., Bellar, A., Lorkowski, S. W., et al. (2024) · eLife · doi:10.7554/elife.92243.2

Metabolic dysfunction-associated steatotic liver disease: pathogenic mechanisms and exercise-induced molecular adaptations

Lei, S., Tao, J., Chen, X., Li, X., & Zhong, S. (2026) · Lipids in Health and Disease · doi:10.1186/s12944-026-03055-5

Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

Helsley, R. N., Varadharajan, V., Brown, A. L., Gromovsky, A. D., Schugar, R. C., Ramachandiran, I., Fung, K., Kabbany, M. N., Banerjee, R., Neumann, C. K. A., et al. (2019) · eLife · doi:10.7554/elife.49882 · Cited by 132 · see citing works

The role of MBOAT7 on fatty liver disease

Caddeo, A. M. (2021) · Gothenburg University Publications Electronic Archive (Gothenburg University)

Understanding the role of Mboat7 in liver disease

Thangapandi, V. R., Knittelfelder, O. L., Brosch, M., Patsenker, E., Vvedenskaya, O., Buch, S., Hinz, S., Hendricks, A., Nati, M., Herrmann, A., et al. (2021) · Zeitschrift für Gastroenterologie · doi:10.1055/s-0041-1733629

MBOAT7 Down-Regulation by Hyperinsulinemia Induces Fat Accumulation in Hepatocytes

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Loss of hepatic Mboat7 leads to liver fibrosis

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