The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Basic and Clinical Immunology of Siglecs
Open accessAbstract
Siglecs are cell‐surface proteins found primarily on hematopoietic cells. By definition, they are members of the immunoglobulin gene super‐family and bind sialic acid. Most contain cytoplasmic tyrosine motifs implicated in cell signaling. This review will first summarize characteristics common and unique to Siglecs, followed by a discussion of each human Siglec in numerical order, mentioning in turn its closest murine ortholog or paralog. Each section will describe its pattern of cellular expression, latest known immune functions, ligands, and signaling pathways, with the focus being predominantly on CD33‐related Siglecs. Potential clinical and therapeutic implications of each Siglec will also be covered.
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Zhang, J. Q., Nicoll, G., Jones, C., & Crocker, P. R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002788200 · Cited by 229
Loss of Siglec expression on T lymphocytes during human evolution
Nguyen, D. H., Hurtado-Ziola, N., Gagneux, P., & Varki, A. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510484103 · Cited by 204
Paul, S. P., Taylor, L. S., Stansbury, E. K., & McVicar, D. W. (2000) · Blood · doi:10.1182/blood.v96.2.483.014k40_483_490 · Cited by 202
Voehringer, D., van Rooijen, N., & Locksley, R. M. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.1106686 · Cited by 173
Cited by
Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
Griciuc, A., Serrano-Pozo, A., Parrado, A. R., Lesinski, A. N., Asselin, C. N., Mullin, K., Hooli, B., Choi, S. H., Hyman, B. T., & Tanzi, R. E. (2013) · Neuron · doi:10.1016/j.neuron.2013.04.014 · Cited by 1,004
Sphingolipid and Glycosphingolipid Metabolic Pathways in the Era of Sphingolipidomics
Merrill, A. H. (2011) · Chemical Reviews · doi:10.1021/cr2002917 · Cited by 785
Induction of myelodysplasia by myeloid-derived suppressor cells
Chen, X., Eksioglu, E. A., Zhou, J., Zhang, L., Djeu, J., Fortenbery, N., Epling-Burnette, P., Van Bijnen, S., Dolstra, H., Cannon, J., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci67580 · Cited by 316
Siglec-G/10 in self-nonself discrimination of innate and adaptive immunity
Chen, G.-Y., Brown, N. K., Zheng, P., & Liu, Y. (2014) · Glycobiology · doi:10.1093/glycob/cwu068 · Cited by 90
Siglec receptors and hiding plaques in Alzheimer's disease
Salminen, A., & Kaarniranta, K. (2009) · Journal of Molecular Medicine · doi:10.1007/s00109-009-0472-1 · Cited by 73
Metadata
- Authors
- Von Gunten, S., & Bochner, B. S.
- Venue
- Annals of the New York Academy of Sciences
- Publisher
- Wiley
- Published
- 2008-11
- Volume
- 1143
- Issue
- 1
- Pages
- 61-82
- ISSN
- 0077-8923 (ISSN-L)
- 1749-6632
- OpenAlex
- W2066248629
- Cited by
- 167
- References
- 4
- FWCI
- 3.35
- Type
- journal article
- Language
- en
- Open access
- green
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