CoChat
Sign Up
Cited by 180Medication Adherence and ComplianceCancer survivorship and careEconomic and Financial Impacts of Cancer

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

The influence of symptoms of disease and side effects of treatment on compliance with cancer therapy.

Richardson, J L, Marks, G, Levine, A·1988·Journal of Clinical Oncology
DOI 10.1200/jco.1988.6.11.1746
Open this paper in CoChat — free account

Abstract

To provide a systematic analysis of how adverse symptoms of disease and side effects of cancer therapy relate to patient noncompliance with treatment, we interviewed 107 patients with hematologic malignancies at the initiation of therapy and 6 months later to collect information on the type, frequency, and difficulty of unpleasant physical effects experienced. Level of compliance was monitored (biochemically and with self-report) on a monthly basis for oral self administration of allopurinol and prednisone. Appointment-keeping to receive infused chemotherapy was also monitored. Nausea was the most frequent side effect experienced. Nausea, fever, and pain were the most difficult physical effects to tolerate when they occurred. Complex treatment regimens and severe diseases related to reports of more physical effects. Younger patients had a more difficult time dealing with these effects than did older patients. Neither the occurrence, frequency, or difficulty dealing with any of the effects related to noncompliance with either of the two self-administered medications. Difficulty with particular effects did relate to noncompliance with clinic appointments to receive infused chemotherapy.

Overview

Integrity signals

Registry

Crossref · 10.1200/jco.1988.6.11.1746

Cites

19 of 19 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Metadata

Authors
Richardson, J. L., Marks, G., & Levine, A.
Affiliations
University of Southern California (US)
ORCID
Venue
Journal of Clinical Oncology
Publisher
American Society of Clinical Oncology (ASCO)
Published
1988-11
Volume
6
Issue
11
Pages
1746-1752
ISSN
  • 0732-183X (ISSN-L)
  • 1527-7755
DOI
10.1200/jco.1988.6.11.1746
OpenAlex
W1832532687
Cited by
180
References
19
Citations by year
2026: 2 · 2025: 3 · 2024: 6 · 2023: 3 · 2022: 6 · 2021: 5 · 2020: 5 · 2019: 9 · 2018: 7 · 2017: 9 · 2016: 6 · 2015: 10 · 2014: 10 · 2013: 5 · 2012: 8
FWCI
1.33
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Clinical Oncology (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Cancer Institute (CA 31151)
Topics
  • Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Economic and Financial Impacts of Cancer
Keywords
treatment non-adherence, cancer treatment side effects, hematologic malignancies, nausea, fever, pain, allopurinol, prednisone, self-administered medication, symptom burden
MeSH terms
Adult, Age Factors, Aged, Aged, 80 and over, Allopurinol, Alopecia, Antineoplastic Combined Chemotherapy Protocols, Female, Humans, Male, Middle Aged, Neoplasms, Patient Compliance, Prognosis, Quality of Life

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review