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Cited by 1,220Cancer survivorship and careHealth Systems, Economic Evaluations, Quality of LifeChildhood Cancer Survivors' Quality of Life

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

The European Organization for Research and Treatment of Cancer breast cancer-specific quality-of-life questionnaire module: first results from a three-country field study

Sprangers, M A, Groenvold, M, Arraras, J I, Franklin, J, te Velde, A, Muller, M, Franzini, L, Williams, A, de Haes, H C, Hopwood, P, Cull, A, Aaronson, N K·1996·Journal of Clinical Oncology
DOI 10.1200/jco.1996.14.10.2756
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Abstract

PURPOSE: To construct a breast cancer-specific quality-of-life questionnaire (QLQ) module to be used in conjunction with the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and to test its reliability and validity cross-culturally. PATIENTS AND METHODS: Module construction took place after the EORTC guidelines for module development. The module--the QLQ-BR23--consists of 23 items covering symptoms and side effects related to different treatment modalities, body image, sexuality, and future perspective. This module was tested in 170 Dutch, 168 Spanish, and 158 American cancer patients at two points in time. The timing for the Dutch and Spanish patients was before and during treatment with radiotherapy or chemotherapy. For the American patients, the questionnaire was administered at admission at the breast clinic and 3 months after the first assessment. RESULTS: Multitrait scaling analysis confirmed the hypothesized structure of four of the five scales. Cronbach's alpha coefficients were, in general, lowest in Spain (range; .46 to .94) and highest in the United States (range; .70 to .91). On the basis of known-groups comparisons, selective scales distinguished clearly between patients differing in disease stage, previous surgery, performance status, and treatment modality, according to expectation. Additionally, selective scales detected change over time as a function of changes in performance status and treatment-induced change. CONCLUSION: These results lend support to the clinical and cross-cultural validity of the QLQ-BR23 as a supplementary questionnaire for assessing specific quality-of-life issues relevant to patients with breast cancer.

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Crossref · 10.1200/jco.1996.14.10.2756

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Metadata

Authors
Sprangers, M. A., Groenvold, M., Arraras, J. I., Franklin, J., te Velde, A., Muller, M., Franzini, L., Williams, A., de Haes, H. C., Hopwood, P., Cull, A., & Aaronson, N. K.
Affiliations
The Netherlands Cancer Institute (NL)
ORCID
Venue
Journal of Clinical Oncology
Publisher
American Society of Clinical Oncology (ASCO)
Published
1996-10
Volume
14
Issue
10
Pages
2756-2768
ISSN
  • 0732-183X (ISSN-L)
  • 1527-7755
DOI
10.1200/jco.1996.14.10.2756
OpenAlex
W1848007259
Cited by
1,220
References
18
Citations by year
2026: 59 · 2025: 74 · 2024: 62 · 2023: 88 · 2022: 83 · 2021: 100 · 2020: 72 · 2019: 58 · 2018: 54 · 2017: 56 · 2016: 35 · 2015: 44 · 2014: 46 · 2013: 40 · 2012: 56
FWCI
3.30
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Clinical Oncology (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
Keywords
breast cancer, quality of life, EORTC QLQ-BR23, EORTC QLQ-C30, cross-cultural validation, questionnaire reliability, questionnaire validity, radiotherapy complications, chemotherapy side effects, body image, sexuality, future perspectives, performance status, Dutch patients, Spanish patients, United States patients
MeSH terms
Adult, Aged, Aged, 80 and over, Breast Neoplasms, Cross-Cultural Comparison, Feasibility Studies, Female, Humans, Language, Middle Aged, Patient Participation, Quality of Life, Surveys and Questionnaires, Reproducibility of Results

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