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Cited by 1,752Cancer survivorship and careHealth Education and ValidationHealth Systems, Economic Evaluations, Quality of Life

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Reliability and validity of the Functional Assessment of Cancer Therapy-Breast quality-of-life instrument.

Brady, M J, Cella, D F, Mo, F, Bonomi, A E, Tulsky, D S, Lloyd, S R, Deasy, S, Cobleigh, M, Shiomoto, G·1997·Journal of Clinical Oncology
DOI 10.1200/jco.1997.15.3.974
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Abstract

PURPOSE: This is the first published report on the validation of the Functional Assessment of Cancer Therapy-Breast (FACT-B), a 44-item self-report instrument designed to measure multidimensional quality of life (QL) in patients with breast cancer. The FACT-B consists of the FACT-General (FACT-G) plus the Breast Cancer Subscale (BCS), which complements the general scale with items specific to QL in breast cancer. The FACT-B was developed with an emphasis on patients' values and brevity and is available in nine languages. METHODS AND RESULTS: Two validation samples were used for this report. The first (n = 47) was tested twice over a 2-month period to assess sensitivity to change. Significant sensitivity to change in performance status rating (PSR) was demonstrated for the FACT-B total score, the Physical Well-Being (PWB) subscale, the Functional Well-Being (FWB) subscale, and the BCS. Sensitivity to change in QL as measured by the Functional Living Index-Cancer (FLIC) was documented in the FACT-B total score, PWB, FWB, and Emotional Well-Being (EWB). Additional validity and reliability data were obtained from a larger sample (n = 295). The alpha coefficient (internal consistency) for the FACT-B total score was high (alpha = .90), with subscale alpha coefficients ranging from .63 to .86. Evidence supported test-retest reliability, as well as convergent, divergent, and known groups validity. CONCLUSION: The FACT-B is appropriate for use in oncology clinical trials, as well as in clinical practice. It demonstrates ease of administration, brevity, reliability, validity, and sensitivity to change.

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Crossref · 10.1200/jco.1997.15.3.974

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Metadata

Authors
Brady, M. J., Cella, D. F., Mo, F., Bonomi, A. E., Tulsky, D. S., Lloyd, S. R., Deasy, S., Cobleigh, M., & Shiomoto, G.
Affiliations
  • Rush University Medical Center (US)
  • Rush University (US)
ORCID
Venue
Journal of Clinical Oncology
Publisher
American Society of Clinical Oncology (ASCO)
Published
1997-03
Volume
15
Issue
3
Pages
974-986
ISSN
  • 0732-183X (ISSN-L)
  • 1527-7755
DOI
10.1200/jco.1997.15.3.974
OpenAlex
W1857624176
Cited by
1,752
References
39
Citations by year
2026: 47 · 2025: 76 · 2024: 77 · 2023: 71 · 2022: 97 · 2021: 88 · 2020: 78 · 2019: 87 · 2018: 83 · 2017: 85 · 2016: 83 · 2015: 73 · 2014: 83 · 2013: 70 · 2012: 86
FWCI
5.28
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Clinical Oncology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (1r29ca051926-01a1)
  • National Cancer Institute (R29CA51926)
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Nursing › Research and Theory › Health Education and Validation
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
Keywords
FACT-B, breast cancer, quality of life, FACT-G, instrument validation, sensitivity to change, test-retest reliability, internal consistency, known-groups validity, convergent validity, discriminant validity, physical well-being, functional well-being, emotional well-being, Functional Living Index-Cancer, self-report questionnaire
MeSH terms
Adult, Aged, Aged, 80 and over, Breast Neoplasms, Female, Humans, Middle Aged, Quality of Life, Self Concept, Sensitivity and Specificity, Severity of Illness Index, Translations, Reproducibility of Results

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