The DOI matches its Crossref record; 66 of the 67 references it cites were found in a registry or an index.
Interventions to Enhance Physical and Psychological Functioning Among Younger Women Who Are Ending Nonhormonal Adjuvant Treatment for Early-Stage Breast Cancer
Open accessAbstract
Purpose: To conduct a clinical trial to determine if an educational intervention and a nutritional intervention could enhance physical and psychological functioning among younger women completing treatment for early-stage breast cancer. Patients and Methods: Younger women (50 years of age or younger, N = 252), within 2 months of having completed active nonhormonal adjuvant therapy, diagnosed with stage 0, I, or II breast cancer with 10 or fewer positive lymph nodes were randomly assigned to a three-arm clinical trial. Women in the control arm of the trial received standard medical care. Women in the two active arms received either an educational intervention, designed to provide information about their illness and enhance adjustment, or a nutritional intervention, designed to promote a more healthy diet. Primary end points included mental functioning, physical functioning, and depressive symptoms. Women were assessed before random assignment, 4 months later (immediately postintervention), and 13 months later (9 months postintervention). Results: Participants assigned to the two active treatment arms had significantly less depressive symptomatology and better physical functioning by 13-month follow-up (differences between the two active arms were nonsignificant). These effects were primarily accounted for by changes in intrusive thoughts, concerns regarding cancer recurrence and mortality, self-concept perceptions, and self-efficacy expectations. Conclusion: Tailored psychosocial interventions can be effectively designed to enhance adjustment among younger women who are completing nonhormonal adjuvant therapy.
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“Yet except for a single study targeting distressed re-entry phase cancer survivors [38], the interventions developed for re-entry phase cancer survivors [39–48] target general cancer survivors rather than the anxious or distressed survivors most in need of help.”
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Metadata
- Authors
- Scheier, M. F., Helgeson, V. S., Schulz, R., Colvin, S., Berga, S., Bridges, M. W., Knapp, J., Gerszten, K., & Pappert, W. S.
- Affiliations
- Emory University (US)
- Corresponding author
- Scheier, Michael F.
- Venue
- Journal of Clinical Oncology
- Published
- 2005-07-01
- Volume
- 23
- Issue
- 19
- Pages
- 4298-4311
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W2172250309
- Cited by
- 125
- References
- 67
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 3 · 2022: 5 · 2021: 4 · 2020: 3 · 2019: 5 · 2018: 4 · 2017: 1 · 2016: 9 · 2015: 4 · 2014: 6 · 2013: 7 · 2012: 6
- FWCI
- 4.41
- Type
- journal article
- Language
- en
- Update notices
- correction (2021-02-01)
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Oncology (publishedVersion)
- PubMed (publishedVersion)
- KiltHub Repository (submittedVersion)
- Figshare (submittedVersion, cc-by)
- KiltHub Repository
- Funders
- University of Pittsburgh
- National Heart, Lung, and Blood Institute (HL65111, HL65112, P50HL065112, P50HL065111)
- National Cancer Institute (CA103730, P20CA103730, CA64711, R01CA064711)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Women's cancer prevention and management
- Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
- Keywords
- early breast cancer, young women, psychosocial interventions, educational intervention, dietary intervention, depressive symptoms, physical function, psychological functioning, intrusive thoughts, self-efficacy, self-concept, adjustment to cancer
- MeSH terms
- Adaptation, Psychological, Breast Neoplasms, Depression, Female, Humans, Mental Health, Middle Aged, Motor Activity, Patient Education as Topic, Treatment Outcome, Chemotherapy, Adjuvant, Radiotherapy, Adjuvant, Nutritional Sciences
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