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Cited by 669

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The Childhood Cancer Survivor Study: A National Cancer Institute–Supported Resource for Outcome and Intervention Research

Open access
Robison, Leslie L., Armstrong, Gregory T., Boice, John D., Chow, Eric J., Davies, Stella M., Donaldson, Sarah S., Green, Daniel M., Hammond, Sue, Meadows, Anna T., Mertens, Ann C., Mulvihill, John J., Nathan, Paul C., Neglia, Joseph P., Packer, Roger J., Rajaraman, Preetha, Sklar, Charles A., Stovall, Marilyn, Strong, Louise C., Yasui, Yutaka, Zeltzer, Lonnie K.·2009·Journal of Clinical Oncology

Abstract

Survival for childhood cancer has increased dramatically over the last 40 years with 5-year survival rates now approaching 80%. For many diagnostic groups, rapid increases in survival began in the 1970s with the broader introduction of multimodality approaches, often including combination chemotherapy with or without radiation therapy. With this increase in rates of survivorship has come the recognition that survivors are at risk for adverse health and quality-of-life outcomes, with risk being influenced by host-, disease-, and treatment-related factors. In 1994, the US National Cancer Institute funded the Childhood Cancer Survivor Study, a multi-institutional research initiative designed to establish a large and extensively characterized cohort of more than 14,000 5-year survivors of childhood and adolescent cancer diagnosed between 1970 and 1986. This ongoing study, which reflects the single most comprehensive body of information ever assembled on childhood and adolescent cancer survivors, provides a dynamic framework and resource to investigate current and future questions about childhood cancer survivors.

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Metadata

Authors
Robison, L. L., Armstrong, G. T., Boice, J. D., Chow, E. J., Davies, S. M., Donaldson, S. S., Green, D. M., Hammond, S., Meadows, A. T., Mertens, A. C., Mulvihill, J. J., Nathan, P. C., Neglia, J. P., Packer, R. J., Rajaraman, P., Sklar, C. A., Stovall, M., Strong, L. C., Yasui, Y., & Zeltzer, L. K.
Venue
Journal of Clinical Oncology
Published
2009-05-10
Volume
27
Issue
14
Pages
2308-2318
ISSN
  • 0732-183X (ISSN-L)
  • 1527-7755
OpenAlex
W2101807916
Cited by
669
References
0
FWCI
35.33
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The Childhood Cancer Survivor Study: A National Cancer Institute–Supported Resource for Outcome and Intervention Research. https://app.cochat.ai/papers/10.1200/jco.2009.22.3339
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Robison, L. L., Armstrong, G. T., Boice, J. D., Chow, E. J., Davies, S. M., Donaldson, S. S., Green, D. M., Hammond, S., Meadows, A. T., Mertens, A. C., Mulvihill, J. J., Nathan, P. C., Neglia, J. P., Packer, R. J., Rajaraman, P., Sklar, C. A., Stovall, M., Strong, L. C., Yasui, Y., & Zeltzer, L. K. (2009). The Childhood Cancer Survivor Study: A National Cancer Institute–Supported Resource for Outcome and Intervention Research. Journal of Clinical Oncology. https://doi.org/10.1200/jco.2009.22.3339

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.