The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
Modern Therapy of Acute Lymphoblastic Leukemia
Abstract
Although acute lymphoblastic leukemia is curable in one third of adult patients, results vary greatly on account of different clinical, immunologic, and cytogenetic/genetic characteristics. These data, along with the kinetics of response to early treatment, help establish the individual risk class with considerable accuracy, and support risk-specific treatments that should warrant optimal results with as little as possible nonrelapse mortality. Modern first-line therapy consists of standard- and high-dose chemotherapy (increasingly inspired to pediatric principles), hematopoietic stem-cell transplantation, and new targeted therapy, all integrated with the analysis of prognostic factors and the study of subclinical residual disease for key therapeutic decisions. These changes are improving long-term outcome, which in ongoing studies is expected close to 50% or greater.
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Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia
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Cited by
Inaba, H., Greaves, M., & Mullighan, C. G. (2013) · The Lancet · doi:10.1016/s0140-6736(12)62187-4 · Cited by 1,074
Malard, F., & Mohty, M. (2020) · The Lancet · doi:10.1016/s0140-6736(19)33018-1 · Cited by 773
The European Hematology Association Roadmap for European Hematology Research: a consensus document
Engert, A., Balduini, C., Brand, A., Coiffier, B., Cordonnier, C., Dohner, H., de Wit, T. D., Eichinger, S., Fibbe, W., Green, T., et al. (2016) · Haematologica · doi:10.3324/haematol.2015.136739 · Cited by 81
“Due to risk-stratified treatment, more optimized treatment protocols, and improved supportive care, the 5-year event-free survival on contemporary treatment protocols is more than 80% for children and is approaching 50% for adults.(112) The short- and long-term side effects of therapy are considerable, however, partic…”
BackgroundXie, M., Lu, Y., Ouyang, G., Li, X., Shi, T., Yang, M., Le, J., Hu, H., Zhang, L., Feng, W., et al. (2023) · British Journal of Haematology · doi:10.1111/bjh.18975 · Cited by 10
Metadata
- Authors
- Bassan, R., & Hoelzer, D.
- Venue
- Journal of Clinical Oncology
- Published
- 2011-02-10
- Volume
- 29
- Issue
- 5
- Pages
- 532-543
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W2081127271
- Cited by
- 485
- References
- 56
- FWCI
- 37.92
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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