The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Pilot Randomized Controlled Trial of Individual Meaning-Centered Psychotherapy for Patients With Advanced Cancer
Open accessAbstract
Purpose: Spiritual well-being and sense of meaning are important concerns for clinicians who care for patients with cancer. We developed Individual Meaning-Centered Psychotherapy (IMCP) to address the need for brief interventions targeting spiritual well-being and meaning for patients with advanced cancer. Patients and Methods: Patients with stage III or IV cancer (N = 120) were randomly assigned to seven sessions of either IMCP or therapeutic massage (TM). Patients were assessed before and after completing the intervention and 2 months postintervention. Primary outcome measures assessed spiritual well-being and quality of life; secondary outcomes included anxiety, depression, hopelessness, symptom burden, and symptom-related distress. Results: Of the 120 participants randomly assigned, 78 (65%) completed the post-treatment assessment and 67 (56%) completed the 2-month follow-up. At the post-treatment assessment, IMCP participants demonstrated significantly greater improvement than the control condition for the primary outcomes of spiritual well-being (b = 0.39; P <.001, including both components of spiritual well-being (sense of meaning: b = 0.34; P = .003 and faith: b = 0.42; P = .03), and quality of life (b = 0.76; P = .013). Significantly greater improvements for IMCP patients were also observed for the secondary outcomes of symptom burden (b = −6.56; P < .001) and symptom-related distress (b = −0.47; P < .001) but not for anxiety, depression, or hopelessness. At the 2-month follow-up assessment, the improvements observed for the IMCP group were no longer significantly greater than those observed for the TM group. Conclusion: IMCP has clear short-term benefits for spiritual suffering and quality of life in patients with advanced cancer. Clinicians working with patients who have advanced cancer should consider IMCP as an approach to enhance quality of life and spiritual well-being.
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In the citing paper
“Additionally, early randomized controlled trials have shown that a meaning-centered therapy, delivered either in a group or individual format, can help raise meaning and purpose in life among people with cancer (32, 33).”
From Purpose in life and use of preventive health care services (2014) · cites this paper as [32]
In the citing paper
“Individual MCP was compared with a control group (massage therapists), and the results showed that MCP produced a greater improvement in meaning in life, spiritual wellbeing, faith, physical symptoms of distress, burnout, and quality of life.”
From Spanish Adaptation of Meaning-Centered Psychotherapy for Participants With Cancer: Study Protocol of a Randomized Control Trial (2022) · cites this paper as [13]
In the citing paper
“The same authors indicated that there were no statistically significant improvements in depression or anxiety.”
From Spanish Adaptation of Meaning-Centered Psychotherapy for Participants With Cancer: Study Protocol of a Randomized Control Trial (2022) · cites this paper as [13]
In the citing paper
“However, the improvement was not sustained at 2 months.”
From Spanish Adaptation of Meaning-Centered Psychotherapy for Participants With Cancer: Study Protocol of a Randomized Control Trial (2022) · cites this paper as [13]
In the citing paper
“Further, many interventions for adults with metastatic cancer (e.g., [14, 23]) are disconnected from the scientific evidence base on how to effectively reduce distress or change behavior.”
In the citing paper
“Palliative care research has developed personally tailored, individually delivered interventions requiring significant resources (e.g., [14, 23, 38])”
In the citing paper
“An increasing number of randomized controlled trials show that purpose in life can be raised.”
From Purpose in life and use of preventive health care services (2014) · cites this paper as [32]
In the citing paper
“findings of physical benefits from interventions designed to enhance R/S indicate that R/S does contribute to better health.39-41”
From Religion, spirituality, and physical health in cancer patients: A meta‐analysis (2015) · cites this paper as [39]
In the citing paper
“Although few spiritually-based interventions have been tested in cancer patients, available data suggest that they may improve quality of life and physical recovery. 39-41”
From Religion, spirituality, and physical health in cancer patients: A meta‐analysis (2015) · cites this paper as [39]
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Breast Cancer, Version 4.2017, NCCN Clinical Practice Guidelines in Oncology
Gradishar, W. J., Anderson, B. O., Balassanian, R., Blair, S. L., Burstein, H. J., Cyr, A. E., ELIAS, A. D., Farrar, W. B., Forero, A., Giordano, S. H., et al. (2018) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2018.0012 · Cited by 1,612
Cancer-Related Fatigue, Version 2.2015
Berger, A. M., Mooney, K. H., Alvarez-Perez, A., BREITBART, W. S., Carpenter, K. M., Cella, D. F., Cleeland, C. S., Dotan, E., Eisenberger, M. A., Escalante, C. P., et al. (2015) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2015.0122 · Cited by 997
Self-citationDistress Management, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology
Riba, M. B., Donovan, K. A., Andersen, B., Braun, I., Breitbart, W. S., Brewer, B. W., Buchmann, L. O., Clark, M. M., Collins, M., Corbett, C., et al. (2019) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2019.0048 · Cited by 871
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Self-citationBreitbart, W., Pessin, H., Rosenfeld, B., Applebaum, A. J., Lichtenthal, W. G., Li, Y., Saracino, R. M., Marziliano, A. M., Masterson, M., Tobias, K., et al. (2018) · Cancer · doi:10.1002/cncr.31539 · Cited by 396
“We developed and tested an individualized version of MCP (individual meaning-centered psychotherapy [IMCP]), which showed strong, albeit preliminary results in a small pilot study.(19) Significant improvements were observed for most outcome variables in comparison with patients receiving an attention-control condition…”
ResultSelf-citation
Metadata
- Authors
- Breitbart, W., Poppito, S., Rosenfeld, B., Vickers, A. J., Li, Y., Abbey, J., Olden, M., Pessin, H., Lichtenthal, W., Sjoberg, D., & Cassileth, B. R.
- Affiliations
- Memorial Sloan Kettering Cancer Center (US)
- ORCID
- Venue
- Journal of Clinical Oncology
- Published
- 2012-04-20
- Volume
- 30
- Issue
- 12
- Pages
- 1304-1309
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- PMC
- PMC3646315
- OpenAlex
- W2099057220
- Cited by
- 426
- References
- 30
- Citations by year
- 2026: 26 · 2025: 31 · 2024: 42 · 2023: 21 · 2022: 32 · 2021: 28 · 2020: 31 · 2019: 32 · 2018: 35 · 2017: 39 · 2016: 19 · 2015: 31 · 2014: 32 · 2013: 23 · 2012: 2
- FWCI
- 32.05
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Clinical Oncology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Cancer Institute (P30CA008748)
- National Center for Complementary and Integrative Health (R21AT001031)
- Topics
- Social Sciences › Health › Religion, Spirituality, and Psychology
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Keywords
- advanced cancer, spiritual well-being, meaningfulness, faith, quality of life, therapeutic massage, symptom burden, brief psychotherapy, spiritual distress
- MeSH terms
- Adaptation, Psychological, Adult, Aged, Aged, 80 and over, Anxiety Disorders, Depressive Disorder, Female, Humans, Lymphoma, Non-Hodgkin, Male, Middle Aged, Neoplasm Staging, Neoplasms, Patient Compliance, Pilot Projects, Prospective Studies, Psychotherapy, Psychotherapy, Group, Quality of Life, Terminal Care, Multivariate Analysis, Linear Models, Treatment Outcome, Terminally Ill, Spirituality, Precision Medicine
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