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Cited by 911

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Advances in Risk Classification and Treatment Strategies for Neuroblastoma

Open access
Pinto, Navin R., Applebaum, Mark A., Volchenboum, Samuel L., Matthay, Katherine K., London, Wendy B., Ambros, Peter F., Nakagawara, Akira, Berthold, Frank, Schleiermacher, Gudrun, Park, Julie R., Valteau-Couanet, Dominique, Pearson, Andrew D.J., Cohn, Susan L.·2015·Journal of Clinical Oncology

Abstract

Risk-based treatment approaches for neuroblastoma have been ongoing for decades. However, the criteria used to define risk in various institutional and cooperative groups were disparate, limiting the ability to compare clinical trial results. To mitigate this problem and enhance collaborative research, homogenous pretreatment patient cohorts have been defined by the International Neuroblastoma Risk Group classification system. During the past 30 years, increasingly intensive, multimodality approaches have been developed to treat patients who are classified as high risk, whereas patients with low- or intermediate-risk neuroblastoma have received reduced therapy. This treatment approach has resulted in improved outcome, although survival for high-risk patients remains poor, emphasizing the need for more effective treatments. Increased knowledge regarding the biology and genetic basis of neuroblastoma has led to the discovery of druggable targets and promising, new therapeutic approaches. Collaborative efforts of institutions and international cooperative groups have led to advances in our understanding of neuroblastoma biology, refinements in risk classification, and stratified treatment strategies, resulting in improved outcome. International collaboration will be even more critical when evaluating therapies designed to treat small cohorts of patients with rare actionable mutations.

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Metadata

Authors
Pinto, N. R., Applebaum, M. A., Volchenboum, S. L., Matthay, K. K., London, W. B., Ambros, P. F., Nakagawara, A., Berthold, F., Schleiermacher, G., Park, J. R., Valteau-Couanet, D., Pearson, A. D. J., & Cohn, S. L.
Venue
Journal of Clinical Oncology
Published
2015-09-20
Volume
33
Issue
27
Pages
3008-3017
ISSN
  • 0732-183X (ISSN-L)
  • 1527-7755
OpenAlex
W2097120541
Cited by
911
References
5
FWCI
31.99
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Advances in Risk Classification and Treatment Strategies for Neuroblastoma. https://app.cochat.ai/papers/10.1200/jco.2014.59.4648
The paper
Pinto, N. R., Applebaum, M. A., Volchenboum, S. L., Matthay, K. K., London, W. B., Ambros, P. F., Nakagawara, A., Berthold, F., Schleiermacher, G., Park, J. R., Valteau-Couanet, D., Pearson, A. D. J., & Cohn, S. L. (2015). Advances in Risk Classification and Treatment Strategies for Neuroblastoma. Journal of Clinical Oncology. https://doi.org/10.1200/jco.2014.59.4648

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.