The DOI matches its Crossref record; 147 of the 147 references it cites were found in a registry or an index.
Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline
Open accessAbstract
PURPOSE: To provide guidance to clinicians regarding therapy for patients with brain metastases from solid tumors. METHODS: ASCO convened an Expert Panel and conducted a systematic review of the literature. RESULTS: Thirty-two randomized trials published in 2008 or later met eligibility criteria and form the primary evidentiary base. RECOMMENDATIONS: Surgery is a reasonable option for patients with brain metastases. Patients with large tumors with mass effect are more likely to benefit than those with multiple brain metastases and/or uncontrolled systemic disease. Patients with symptomatic brain metastases should receive local therapy regardless of the systemic therapy used. For patients with asymptomatic brain metastases, local therapy should not be deferred unless deferral is specifically recommended in this guideline. The decision to defer local therapy should be based on a multidisciplinary discussion of the potential benefits and harms that the patient may experience. Several regimens were recommended for non–small-cell lung cancer, breast cancer, and melanoma. For patients with asymptomatic brain metastases and no systemic therapy options, stereotactic radiosurgery (SRS) alone should be offered to patients with one to four unresected brain metastases, excluding small-cell lung carcinoma. SRS alone to the surgical cavity should be offered to patients with one to two resected brain metastases. SRS, whole brain radiation therapy, or their combination are reasonable options for other patients. Memantine and hippocampal avoidance should be offered to patients who receive whole brain radiation therapy and have no hippocampal lesions and 4 months or more expected survival. Patients with asymptomatic brain metastases with either Karnofsky Performance Status ≤ 50 or Karnofsky Performance Status < 70 with no systemic therapy options do not derive benefit from radiation therapy. Additional information is available at www.asco.org/neurooncology-guidelines .
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RoB 2: a revised tool for assessing risk of bias in randomised trials
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Postoperative Radiotherapy in the Treatment of Single Metastases to the Brain: A Randomized Trial
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Management of Metastatic Clear Cell Renal Cell Carcinoma: ASCO Guideline
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Mehta, M. P., Gondi, V., Ahluwalia, M. S., Roberge, D., Sio, T. T. W., Trifiletti, D. M., Muanza, T., Krpan, A. M., Zhu, Z., Ramakrishna, N. R., et al. (2026) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2025.08.066 · Cited by 9
Self-citationAkkus Yildirim, B., Tutun, B., Durak, G., Yildirim, E. B., Uysal, E., Erturk, S. M., & Bagci, U. (2025) · Communications Medicine · doi:10.1038/s43856-025-01315-6 · Cited by 2
Metadata
- Authors
- Vogelbaum, M. A., Brown, P. D., Messersmith, H., Brastianos, P. K., Burri, S., Cahill, D., Dunn, I. F., Gaspar, L. E., Gatson, N. T. N., Gondi, V., Jordan, J. T., Lassman, A. B., Maues, J., Mohile, N., Redjal, N., Stevens, G., Sulman, E., van den Bent, M., Wallace, H. J., Weinberg, J. S., Zadeh, G., & Schiff, D.
- Venue
- Journal of Clinical Oncology
- Published
- 2022-02-10
- Volume
- 40
- Issue
- 5
- Pages
- 492-516
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W4200190043
- Cited by
- 832
- References
- 147
- FWCI
- 64.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Vogelbaum, M. A., Brown, P. D., Messersmith, H., Brastianos, P. K., Burri, S., Cahill, D., Dunn, I. F., Gaspar, L. E., Gatson, N. T. N., Gondi, V., Jordan, J. T., Lassman, A. B., Maues, J., Mohile, N., Redjal, N., Stevens, G., Sulman, E., van den Bent, M., Wallace, H. J., . . . Schiff, D. (2022). Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline. Journal of Clinical Oncology. https://doi.org/10.1200/jco.21.02314
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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