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Analysis of Incomplete Multivariate Data
Abstract
The last two decades have seen enormous developments in statistical methods for incomplete data. The EM algorithm and its extensions, multiple imputation, and Markov Chain Monte Carlo provide a set of flexible and reliable tools from inference in large classes of missing-data problems. Yet, in practical terms, those developments have had surprisingly little impact on the way most data analysts handle missing values on a routine basis. Analysis of Incomplete Multivariate Data helps bridge the gap between theory and practice, making these missing-data tools accessible to a broad audience. It presents a unified, Bayesian approach to the analysis of incomplete multivariate data, covering datasets in which the variables are continuous, categorical, or both. The focus is applied, where necessary, to help readers thoroughly understand the statistical properties of those methods, and the behavior of the accompanying algorithms.All techniques are illustrated with real data examples, with extended discussion and practical advice. All of the algorithms described in this book have been implemented by the author for general use in the statistical languages S and S Plus. The software is available free of charge on the Internet.
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“Methods to deal with data missing at random (MAR) fall into three broad classes [ 108 , 111 ]: likelihood-based approaches [ 112 ], weighted estimation [ 113 ] and multiple imputation [ 111 , 114 ].”
From Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration (2007) · cites this paper as [111]
In the citing paper
“The percentage of missing values in the WAI-TECH-SF, PHQ-9, and CEQ scores ranged from 0% to 1.6%. After testing that the values were missing at random using Little’s MCAR test (p > 0.05), they were imputed using the Expectation–Maximization Algorithm method [40].”
In the citing paper
“Parallel Analysis [40] showed that one factor had to be retained because only one factor had an eigenvalue (raw data eigenvalue = 9.08) greater than the eigenvalue at the 95th percentile for randomly generated data (95th percentile eigenvalue = 1.53) [48].”
In the citing paper
“For the remaining part of the survey, we utilized a planned missing data design or “matrix sampling” (Schafer, 1997; Graham et al., 2006) to keep the burden on participants to a minimum, and used multiple imputations to deal with the uncertainty related to missing data (as described in detail in Section Multiple Imputation Procedure below).”
From Using Genetic Algorithms in a Large Nationally Representative American Sample to Abbreviate the Multidimensional Experiential Avoidance Questionnaire (2016) · cites this paper as Schafer, 1997
In the citing paper
“Missing data for outcomes at six weeks, six months and 12 months were imputed using multiple imputation based upon the Markov chain Monte Carlo method (Schafer, 1997) and maximum likelihood imputation based upon the Expectation-Maximization (EM) algorithm.”
From A randomised clinical trial to evaluate the acceptability and efficacy of an early phase, online, guided augmentation of outpatient care for adults with anorexia nervosa (2020) · cites this paper as Schafer, 1997
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“Other methods rely on maximum likelihood-based estimations of missing data, like the expectation maximization (EM) algorithm [10-12].”
BackgroundMethodInfluentialThe Counseling Opportunity Structure: Examining Correlates of Four-Year College-Going Rates
Engberg, M. E., & Gilbert, A. J. (2013) · Research in Higher Education · doi:10.1007/s11162-013-9309-4 · Cited by 101
COMPARISON OF ALTERNATIVE STRATEGIES FOR ANALYSIS OF LONGITUDINAL TRIALS WITH DROPOUTS
Liu, G. F., & Gould, A. L. (2002) · Journal of Biopharmaceutical Statistics · doi:10.1081/bip-120015744 · Cited by 101
Wickes, R., Hipp, J. R., Sargeant, E., & Homel, R. (2013) · American Journal of Community Psychology · doi:10.1007/s10464-013-9582-6 · Cited by 102
Evaluation of software for multiple imputation of semi-continuous data
Yu, L.-M., Burton, A., & Rivero-Arias, O. (2007) · Statistical Methods in Medical Research · doi:10.1177/0962280206074464 · Cited by 117
Heterogeneity of Diabetes Outcomes Among Asians and Pacific Islanders in the U.S.
Kanaya, A. M., Adler, N. E., Moffet, H. H., Liu, J. Y., Schillinger, D., Adams, A. S., Ahmed, A. T., & Karter, A. J. (2011) · Diabetes Care · doi:10.2337/dc10-1964 · Cited by 102
Miethe, T. D., Regoeczi, W. C., & Drass, K. A. (2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511499487 · Cited by 101
Sahdra, B. K., Ciarrochi, J., Parker, P., & Scrucca, L. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00189 · Cited by 100
García‐Aymerich, J., Benet, M., Saeys, Y., Pinart, M., Basagaña, X., Smit, H. A., Siroux, V., Just, J., Momas, I., Rancière, F., et al. (2015) · Allergy · doi:10.1111/all.12640 · Cited by 109
“We assessed the presence and patterns of missing values and, assuming the missing-at-random hypothesis (18), we used multiple imputation (20 imputed data sets) with the method of chained equations (19).”
Adiposity and Incidence of Heart Failure Hospitalization and Mortality
Levitan, E. B., Yang, A. Z., Wolk, A., & Mittleman, M. A. (2009) · Circulation Heart Failure · doi:10.1161/circheartfailure.108.794099 · Cited by 98
Metadata
- Authors
- Schafer, J. L.
- Corresponding author
- Schafer, J.L.
- Venue
- Chapman & Hall/CRC eBooks
- Publisher
- Chapman and Hall/CRC
- Published
- 1997-08-01
- Volume
- 1997
- Issue
- 1997
- Pages
- 1-99
- OpenAlex
- W4300187280
- Semantic Scholar
- d9b083d7366dc17f2a71d7799f417707c86a37d3
- Cited by
- 6,012
- References
- 0
- Citations by year
- 2026: 92 · 2025: 128 · 2024: 161 · 2023: 143 · 2022: 197 · 2021: 277 · 2020: 222 · 2019: 288 · 2018: 261 · 2017: 264 · 2016: 308 · 2015: 323 · 2014: 322 · 2013: 292 · 2012: 320
- FWCI
- 17.88
- Type
- book
- Language
- en
- Open access
- closed
- Locations
- Chapman & Hall/CRC eBooks (publishedVersion)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
- Physical Sciences › Mathematics › Statistics and Probability › Markov Chains and Monte Carlo Methods
- Physical Sciences › Computer Science › Artificial Intelligence › Bayesian Methods and Mixture Models
- Keywords
- missing data, Bayesian analysis, expectation-maximization algorithm, multiple imputation, Markov chain Monte Carlo
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