High Performance Liquid Chromatography in Phytochemical Analysis

Monika Waksmundzka‐Hajnos; Joseph Sherma

doi:10.1201/b10320

Cited by 130Chromatography in Natural ProductsTraditional Chinese Medicine AnalysisAnalytical Methods in Pharmaceuticals

High Performance Liquid Chromatography in Phytochemical Analysis

Monika Waksmundzka‐Hajnos, Joseph Sherma·2010·CRC Press eBooks

DOI 10.1201/b10320

Open this paper in CoChat — free account

Abstract

The powerful, efficient technique of high performance liquid chromatography (HPLC) is essential to the standardization of plant-based drugs, identification of plant material, and creation of new herbal medicines. Filling the void in this critical area, High Performance Liquid Chromatography in Phytochemical Analysis is the first book to give a comp

Integrity signals

Registry

Crossref · 10.1201/b10320

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The most commonly used HPLC systems are variants on a C18-RP-column eluted with a linear gradient of methanol or acetonitrile in water.
“The most commonly used HPLC systems are variants on a C 18 -RP-column eluted with a linear gradient of methanol or acetonitrile in water.”
From Ecdysteroids (2021) · cites this paper as [128]

Sorted by citations

Supercritical fluid extraction of vegetable matrices: Applications, trends and future perspectives of a convincing green technology
de Melo, M. M. R., Silvestre, A. J. D., & Silva, C. M. (2014) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2014.04.007 · Cited by 526 · see citing works
Natural product isolation – how to get from biological material to pure compounds
Bučar, F., Wube, A. A., & Schmid, M. G. (2013) · Natural Product Reports · doi:10.1039/c3np20106f · Cited by 376 · see citing works
Authenticity of essential oils
Do, T. K. T., Hadji-Minaglou, F., Antoniotti, S., & Fernàndez, X. (2014) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2014.10.007 · Cited by 283 · see citing works
“Although presenting the same physicochemical properties, except for their optical activity, enantiomers can exhibit divergent biological activities, one enantiomer being harmless while the other is toxic, so appropriate, efficient chemical analyses are essential [57].”
Background
Application of HPLC and ESI-MS techniques in the analysis of phenolic acids and flavonoids from green leafy vegetables (GLVs)
Kumar, B. (2017) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2017.06.005 · Cited by 198 · see citing works
Comparison of analytical techniques for the identification of bioactive compounds from natural products
Ciesla, L. M., & Moaddel, R. (2016) · Natural Product Reports · doi:10.1039/c6np00016a · Cited by 158 · see citing works
Bioactive compounds from microalgae: Current development and prospects
Fu, W., Nelson, D. R., Yi, Z., Xu, M., Khraiwesh, B., Jijakli, K., Chaiboonchoe, A., Alzahmi, A., Al-Khairy, D., Brynjolfsson, S., et al. (2017) · Studies in natural products chemistry · doi:10.1016/b978-0-444-63929-5.00006-1 · Cited by 121 · see citing works
Identification of phenolic compounds in soursop (Annona muricata) pulp by high-performance liquid chromatography with diode array and electrospray ionization mass spectrometric detection
Jiménez, V. M., Gruschwitz, M., Schweiggert, R. M., Carle, R., & Esquivel, P. (2014) · Food Research International · doi:10.1016/j.foodres.2014.05.051 · Cited by 105 · see citing works
Effects of Citrullus colocynthis L. in a rat model of diabetic neuropathy
Ostovar, M., Akbari, A., Anbardar, M. H., et al. (2019) · Journal of Chinese Integrative Medicine · doi:10.1016/j.joim.2019.12.002 · Cited by 69 · see citing works
Novel trends and applications of multidimensional chromatography in the analysis of food, cosmetics and medicine bearing essential oils
Rasheed, D. M., Serag, A., Shakour, Z. T. A., et al. (2020) · Talanta · doi:10.1016/j.talanta.2020.121710 · Cited by 67 · see citing works
Review: DNA Barcoding and Chromatography Fingerprints for the Authentication of Botanicals in Herbal Medicinal Products
Abubakar, B. M., Salleh, F. M., Shamsir, M. S., & Wagiran, A. (2017) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2017/1352948 · Cited by 66 · see citing works
Significance of Chromatographic Techniques in Pharmaceutical Analysis
Parys, W., Dołowy, M., & Pyka, A. (2022) · Processes · doi:10.3390/pr10010172 · Cited by 61 · see citing works
Caryophyllene Oxide, the Active Compound Isolated from Leaves of Hymenaea courbaril L. (Fabaceae) with Antiproliferative and Apoptotic Effects on PC-3 Androgen-Independent Prostate Cancer Cell Line
Delgado, C., Méndez-Callejas, G., & Celis, C. A. (2021) · Molecules · doi:10.3390/molecules26206142 · Cited by 57 · see citing works
Obtaining and characterization of anthocyanins from Euterpe oleracea (açaí) dry extract for nutraceutical and food preparations
da Silva, H. R., de Assis, D. D. C., Prada, A. L., et al. (2019) · Revista Brasileira de Farmacognosia · doi:10.1016/j.bjp.2019.03.004 · Cited by 50 · see citing works
Ecdysteroids
Lafont, R., Balducci, C., & Dinan, L. (2021) · Encyclopedia · doi:10.3390/encyclopedia1040096 · Cited by 49 · see citing works
Total Polyphenols Content, Antioxidant and Antimicrobial Activities of Leaves of Solanum elaeagnifolium Cav. from Morocco
Bouslamti, M., Barnossi, A. E., Kara, M., Alotaibi, B. S., Kamaly, O. M. A., Assouguem, A., Lyoussi, B., & Benjelloun, A. S. (2022) · Molecules · doi:10.3390/molecules27134322 · Cited by 50 · see citing works
“Several polyphenols have been identified [5].”
Advanced development in phytochemicals analysis of medicine and food dual purposes plants used in China (2011–2014)
Zhao, J., Ge, L., Xiong, W., Leong, F., Huang, L., & Li, S. (2015) · Journal of Chromatography A · doi:10.1016/j.chroma.2015.09.006 · Cited by 46 · see citing works
Medicinal plants used in Lesotho for treatment of reproductive and post reproductive problems
Moteetee, A. N., & Seleteng‐Kose, L. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.10.062 · Cited by 44 · see citing works
The antimicrobial activity of the alcohols fromMusca domestica
Gołębiowski, M., Dawgul, M. A., Kamysz, W., et al. (2012) · Journal of Experimental Biology · doi:10.1242/jeb.073155 · Cited by 42 · see citing works
Comparison of the Polyphenolic Profile of Medicago sativa L. and Trifolium pratense L. Sprouts in Different Germination Stages Using the UHPLC-Q Exactive Hybrid Quadrupole Orbitrap High-Resolution Mass Spectrometry
Chiriac, E. R., Chițescu, C. L., Borda, D., Lupoae, M., Gîrd, C. E., Geană, E., Blaga, G.-V., & Boscencu, R. (2020) · Molecules · doi:10.3390/molecules25102321 · Cited by 43 · see citing works
The chemical composition of cuticular waxes from leaves of the gboma eggplant (Solanum macrocarpon L.)
Haliński, Ł. P., Paszkiewicz, M., Gołębiowski, M., et al. (2011) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2011.06.004 · Cited by 39 · see citing works
Bioassay guided fractionation-an emerging technique influence the isolation, identification and characterization of lead phytomolecules
Malviya, N., & Malviya, S. (2017) · International Journal of Hospital Pharmacy · doi:10.28933/ijhp-2017-07-0901 · Cited by 38 · see citing works
Recent Advances in the Analysis of Rosmarinic Acid From Herbs in the Lamiaceae Family
Sik, B., Kapcsándi, V., Székelyhidi, R., Hanczné, E. L., & Ajtony, Z. (2019) · Natural Product Communications · doi:10.1177/1934578x19864216 · Cited by 36 · see citing works
Analysis of diterpenes and diterpenoids
Eksi, G., Kurbanoğlu, S., & Erdem, S. A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816455-6.00009-3 · Cited by 39 · see citing works
Potential Application of Cornelian Cherry Extract on Broiler Chickens: Growth, Expression of Antioxidant Biomarker and Glucose Transport Genes, and Oxidative Stability of Frozen Meat
Ibrahim, D., Moustafa, A., Metwally, A. S., NASSAN, M. A., Abdallah, K. M. E., Eldemery, F., Tufarelli, V., Laudadio, V., & Kishawy, A. T. Y. (2021) · Animals · doi:10.3390/ani11041038 · Cited by 36 · see citing works
“Moreover, the high content of iridoids, such as cyclopentanopyran, found in CCE provides pharmacological properties such as antibiotic and anti-inflammatory effects [25].”
Background
Isolation and characterization of bioactive polyacetylenes Panax ginseng Meyer roots
Yeo, C.-R., Yong, J.-J., & Popovich, D. G. (2017) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2017.02.054 · Cited by 32 · see citing works
Phytochemicals in Breast Cancer Prevention and Treatment: A Comprehensive Review
Wali, A. F., Pillai, J. R., Talath, S., Shivappa, P., Sridhar, S. B., El‐Tanani, M., Rangraze, I. R., Mohamed, O. I., & Ani, N. N. A. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47010030 · Cited by 32 · see citing works
Furanocoumarins
(2014) · Studies in natural products chemistry · doi:10.1016/b978-0-444-63430-6.00005-9 · Cited by 33 · see citing works
Anti-inflammatory activities of Waltheria indica extracts by modulating expression of IL-1B, TNF-α, TNFRII and NF-κB in human macrophages
Laczkó, R., Chang, A., Watanabe, L., Petelo, M., Kahaleua, K., Bingham, J., & Csiszár, K. (2019) · Inflammopharmacology · doi:10.1007/s10787-019-00658-6 · Cited by 31 · see citing works
Antioxidant Activity and Spectroscopic Characteristics of Extractable and Non-Extractable Phenolics from Terminalia sericea Burch. ex DC.
Anokwuru, C. P., Sigidi, M., Mounanga, M. B., et al. (2018) · Molecules · doi:10.3390/molecules23061303 · Cited by 29 · see citing works
Development and Validation of the UPLC-DAD Methodology for the Detection of Triterpenoids and Phytosterols in Fruit Samples of Vaccinium macrocarpon Aiton and Vaccinium oxycoccos L.
Šedbarė, R., Raudonė, L., Žvikas, V., et al. (2022) · Molecules · doi:10.3390/molecules27144403 · Cited by 28 · see citing works
Identification of some Bioactive Metabolites in a Fractionated Methanol Extract from Ipomoea aquatica (Aerial Parts) through TLC, HPLC, UPLC‐ESI‐QTOF‐MS and LC‐SPE‐NMR Fingerprints Analyses
Gad, M. H., Tuenter, E., El-Sawi, N. M., et al. (2017) · Phytochemical Analysis · doi:10.1002/pca.2709 · Cited by 27 · see citing works
Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum Indicum Fruits
Babu, P. J., Sharma, P., Saranya, S., et al. (2013) · Nanomaterials and Nanotechnology · doi:10.5772/56608 · Cited by 25 · see citing works
Green extraction of secondary metabolites from plants: Obstacles, current status, and trends
Torres-Ortiz, D. A., García‐Alcocer, G., Berumen, L. C., & Estévez, M. (2024) · Sustainable Chemistry for the Environment · doi:10.1016/j.scenv.2024.100157 · Cited by 26 · see citing works
A novel approach to the quantitative detection of anabolic steroids in bovine muscle tissue by means of a hybrid quadrupole time-of-flight-mass spectrometry instrument
Bussche, J. V., Decloedt, A. I., Meulebroek, L. V., et al. (2014) · Journal of Chromatography A · doi:10.1016/j.chroma.2014.07.087 · Cited by 23 · see citing works
Secondary metabolites isolation in natural products chemistry: Comparison of two semipreparative chromatographic techniques (high pressure liquid chromatography and high performance thin-layer chromatography)
Do, T. K. T., Hadji-Minaglou, F., Antoniotti, S., et al. (2013) · Journal of Chromatography A · doi:10.1016/j.chroma.2013.11.046 · Cited by 23 · see citing works
“HPLC however is the most frequently used [1,5,6].”
Claimed Effects, Outcome Variables and Methods of Measurement for Health Claims Proposed Under European Community Regulation 1924/2006 in the Framework of Maintenance of Skin Function
Martini, D., Angelino, D., Cortelazzi, C., Zavaroni, I., Bedogni, G., Musci, M., Pruneti, C. A., Passeri, G., Ventura, M., Galli, D., et al. (2017) · Nutrients · doi:10.3390/nu10010007 · Cited by 23 · see citing works
Neophytadiene: Biological activities and drug development prospects
Rajeswaran, S., & Rajan, D. K. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156872 · Cited by 23 · see citing works
Bioactivity of Acanthus mollis – Contribution of benzoxazinoids and phenylpropanoids
Matos, P., Figueirinha, A., Paranhos, A., et al. (2018) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2018.09.013 · Cited by 20 · see citing works
HPLC Analysis of Kaempherol and Quercetin Derivatives Isolated by Different Extraction Techniques from Plant Matrix
Skalicka‐Woźniak, K., Szypowski, J., & Głowniak, K. (2011) · Journal of AOAC International · doi:10.1093/jaoac/94.1.17 · Cited by 20 · see citing works
Hyphenated analytical techniques for validation of herbal medicine
Mukherjee, P. K., Kar, A., Biswas, S., et al. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-85542-6.00038-x · Cited by 18 · see citing works
Age and sex-related changes in cytokinins, auxins and abscisic acid in a centenarian relict herbaceous perennial
Oñate, M., Garcia, M. B., & Munné‐Bosch, S. (2011) · Planta · doi:10.1007/s00425-011-1513-x · Cited by 18 · see citing works
Assessing the iron chelation capacity of goat casein digest isolates
Smialowska, A., Matia‐Merino, L., & Carr, A. J. (2017) · Journal of Dairy Science · doi:10.3168/jds.2016-12090 · Cited by 18 · see citing works
Statistical modelling coupled with LC-MS analysis to predict human upper intestinal absorption of phytochemical mixtures
Selby-Pham, S. N. B., Howell, K. S., Dunshea, F. R., Ludbey, J., Lutz, A., & Bennett, L. E. (2017) · Food Chemistry · doi:10.1016/j.foodchem.2017.10.102 · Cited by 15 · see citing works
Phytochemical, Antioxidant and Antimicrobial Profiles of Extracts of Daphne alpina (Thymelaeaceae) L Leaf and Twig from Mt Kopaonik (Serbia)
Sovrlić, M., Vasiljevic, P. J., Jušković, M. Z., Mašković, P., & Manojlović, N. (2015) · Tropical Journal of Pharmaceutical Research · doi:10.4314/tjpr.v14i7.17 · Cited by 15 · see citing works
“alpina was coumarin daphnin (8-hydroxy-7-β-Dglucosyloxycoumarin) by Vauquelin 1812 [3].”
Background
Synergistic Effect of DIBOA and Verbascoside from Acanthus mollis Leaf on Tyrosinase Inhibition
Matos, P., Paranhos, A., Batista, M. T., & Figueirinha, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113536 · Cited by 16 · see citing works
Influences of freeze‐ and spray‐drying vs. encapsulation with soy and whey proteins on gastrointestinal stability and antioxidant activity of Mediterranean aromatic herbs
Bilušić, T., Drvenica, I. T., Kalušević, A., et al. (2020) · International Journal of Food Science & Technology · doi:10.1111/ijfs.14774 · Cited by 14 · see citing works
Extraction of Functional Components from Freeze-Dried Angelica furcijuga Leaves Using Supercritical Carbon Dioxide
Hoshino, Y., Diono, W., Machmudah, S., Hirayama, S., Kanda, H., Hoshino, M., & Goto, M. (2022) · ACS Omega · doi:10.1021/acsomega.1c06105 · Cited by 13 · see citing works
Response surface methodology based on central composite design accompanied by multivariate curve resolution to model gradient hydrophilic interaction liquid chromatography: Prediction of separation for five major opium alkaloids
Taheri, M., Bagheri, M., Moazeni‐Pourasil, R. S., et al. (2017) · Journal of Separation Science · doi:10.1002/jssc.201700416 · Cited by 13 · see citing works
Hyptis mociniana: phytochemical fingerprint and photochemoprotective effect against UV-B radiation-induced erythema and skin carcinogenesis
Espinosa‐González, A. M., Estrella-Parra, E. A., Nolasco-Ontiveros, E., García‐Bores, A. M., García‐Hernández, R., López–Urrutia, E., Campos, J. E., González-Valle, M. D. R., Benítez-Flores, J. D. C., Céspedes, C. L., et al. (2021) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112095 · Cited by 13 · see citing works
A Review on Methods Used in Analysis of Microalgae Lipid Composition
NGUYEN, H. T. D., Ramli, A., & Kee, L. M. (2017) · Journal of the Japan Institute of Energy · doi:10.3775/jie.96.532 · Cited by 12 · see citing works
Efeito do solvente na extração de ácidos clorogênicos, cafeína e trigonelina em Coffea arabica
Moreira, I., Scheel, G. L., Hatumura, P. H., et al. (2014) · Química Nova · doi:10.1590/s0100-40422014000100008 · Cited by 12 · see citing works
Ultra-High Performance Liquid Chromatography (UHPLC) Method for the Determination of Limonene in Sweet Orange (Citrus sinensis) Oil: Implications for Limonene Stability
Bernart, M. W. (2015) · Journal of AOAC International · doi:10.5740/jaoacint.14-157 · Cited by 11 · see citing works
Phytochemical Markers: Classification, Applications and Isolation
Desai, S., & Tatke, P. A. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666190709203239 · Cited by 10 · see citing works
Research for the lichen Usnea barbata metabolites
Bazarnova, J. G., Politaeva, N., & Lyskova, N. (2018) · Zeitschrift für Naturforschung C · doi:10.1515/znc-2017-0177 · Cited by 10 · see citing works
Selective Anti-proliferative Activity of Indole Alkaloids from Rhazya stricta Decne Leaves
Abdul-Hameed, Z. H., Alarif, W. M., Omer, A. M. S., et al. (2019) · Letters in Organic Chemistry · doi:10.2174/1570178616666190101095417 · Cited by 10 · see citing works
Analytical Methods for Isolation, Separation and Identification of Selected Furanocoumarins in Plant Material
Szewczyk, K. D. S., & Kock, A. B. (2012) · InTech eBooks · doi:10.5772/27495 · Cited by 10 · see citing works
Determination of trace amount of enantiomeric impurity in therapeutic nicotine derivative using capillary electrophoresis with new imaging technology detection
Dahab, A. A., & Smith, N. W. (2011) · Journal of Separation Science · doi:10.1002/jssc.201100513 · Cited by 10 · see citing works
Silica Gel and its Derivatization for Liquid Chromatography
Skoczylas, M., Krzemińska, K., Bocian, S., et al. (2017) · Encyclopedia of Analytical Chemistry · doi:10.1002/9780470027318.a5915.pub3 · Cited by 10 · see citing works
Plectranthus ecklonii Benth: A Comprehensive Review Into its Phytochemistry and Exerted Biological Activities
Antão, A. M. R., Bangay, G., Domínguez-Martín, E. M., Dı́az-Lanza, A. M., & Rijo, P. M. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.768268 · Cited by 9 · see citing works
Advanced Spectroscopic Detectors for Identification and Quantification
Wolfender, J., Bohni, N., Ndjoko-Ioset, K., & Edison, A. S. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-415807-8.00016-x · Cited by 9 · see citing works
Separation and Quantification of Selected Sapogenins Extracted from Nettle, White Dead-Nettle, Common Soapwort and Washnut
Ligor, M., Kiełbasa, A., Ratiu, I., et al. (2021) · Molecules · doi:10.3390/molecules26247705 · Cited by 9 · see citing works
Marine Polyacetylenes: Distribution, Biological Properties, and Synthesis
Legrave, N. M., Fahmi, E. M., Mohamed, M., et al. (2015) · Studies in natural products chemistry · doi:10.1016/b978-0-444-63473-3.00008-3 · Cited by 9 · see citing works
phytochemical investigations of Iraqi Abrus precatorius Linn. plant
Nassir, Z. S., & Khadem, E. (2018) · Iraqi Journal of Pharmaceutical Sciences · doi:10.31351/vol27iss1pp30-38 · Cited by 8 · see citing works
“A-Chemical structure of abrine, (2S)-3-(1H-indole-3-yl)-2-(methylamino) propionic acid, (C12H14O2N2) ((21)), B-Figure (1.”
Identification and Isolation Techniques for Plant Growth Inhibitors in Rice
Anh, N. T. H., Anh, L. H., Mai, N. P., et al. (2023) · Separations · doi:10.3390/separations10020105 · Cited by 8 · see citing works
Coumarins: Analytical and Preparative Techniques
Skalicka‐Woźniak, K., & Głowniak, K. (2014) · Encyclopedia of Analytical Chemistry · doi:10.1002/9780470027318.a9925 · Cited by 8 · see citing works
Development of a Simultaneous Normal-Phase HPLC Analysis of Lignans, Tocopherols, Phytosterols, and Squalene in Sesame Oil Samples
Yuenyong, J., Bennett, C., Jiamyangyuen, S., et al. (2024) · Foods · doi:10.3390/foods13091368 · Cited by 7 · see citing works
High-Performance Liquid Chromatography for Analysis of Herbal Drugs
Mukherjee, P. K. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813374-3.00010-7 · Cited by 7 · see citing works
Identification and analysis of toxic phytochemicals
Salem, M. A., Serag, A., El‐Seedi, H. R., et al. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-821556-2.00015-3 · Cited by 7 · see citing works
Use of Friulan saffron in the production of craft beer
Buiatti, S., Guglielmotti, M., Bertin, F., et al. (2023) · European Food Research and Technology · doi:10.1007/s00217-023-04389-5 · Cited by 6 · see citing works
Simultaneous Quantification of Eight Marker Compounds in Yongdamsagan-Tang Using a High-Performance Liquid Chromatography Equipped with Photodiode Array Detector
Seo, C., & Shin, H. (2017) · Journal of Chromatographic Science · doi:10.1093/chromsci/bmx053 · Cited by 6 · see citing works
“Chlorogenic acid (1), gentiopicroside (2), liquiritin apioside (3), liquiritin (4), nodakenin (5), baicalin (6), wogonoside (7) and glycyrrhizin (8).”
BackgroundMethod
Application of Biotechnology in Producing Plant Bio-active Compounds
Pereira, G. C. (2019) · Springer eBooks · doi:10.1007/978-981-13-7438-8_3 · Cited by 7 · see citing works
Physicochemical characterizations of safranal-β-cyclodextrin inclusion complexes prepared by supercritical carbon dioxide and conventional methods
Abbaszadegan, S., Al-Marzouqi, A. H., Salem, A. A., et al. (2015) · Journal of Inclusion Phenomena and Macrocyclic Chemistry · doi:10.1007/s10847-015-0555-2 · Cited by 6 · see citing works
Use of mass spectrometry as a tool for the search or identification of flavonoids in Urticaceae
Gonçalves, F. M. B., de Sousa, A. L., & de Oliveira, R. R. (2023) · Rodriguésia · doi:10.1590/2175-7860202374049 · Cited by 5 · see citing works
“The flavonoids O -glycosides have sugar units substituents attached to an aglycone hydroxyl group, usually at positions C -3 or C -7, while in the case of C -glycosides flavonoids, sugars are linked to aglycone by a carbon-carbon bond at the C -6 or C -8 position (Waksmundzka-Hajnos & Sherma 2011).”
Background
The potential of Amaranth Grain-Based Flour in Complementary Feeding: A Community-Based Approach in Kongwa District, Tanzania.
Kayanda, R., Mogha, N. G., Makori, N., et al. (2025) · Current Research in Nutrition and Food Science Journal · doi:10.12944/crnfsj.13.2.16 · Cited by 5 · see citing works
Advanced spectroscopic detectors for identification and quantification: Nuclear magnetic resonance
Bohni, N., Ndjoko-Ioset, K., Edison, A. S., & Wolfender, J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805393-5.00020-8 · Cited by 7 · see citing works
Coumarins from the Roots of Angelica archangelica and Antibacterial Activity Against Methicillin Resistant Staphylococcus aureus
Alloush, M., Mallion, C., Sarker, S. D., et al. (2022) · Dhaka University Journal of Pharmaceutical Sciences · doi:10.3329/dujps.v20i3.59793 · Cited by 4 · see citing works
Advances in Testing for Adulteration of Food Supplements
El-Ahmady, S. H., & Ashour, M. L. (2016) · Elsevier eBooks · doi:10.1016/b978-0-08-100220-9.00024-2 · Cited by 4 · see citing works
Antiviral activity and mechanisms of action of atropine, rutin, and hypoxanthine against tomato Brown rugose fruit virus
Salehzadeh, M., Izadpanah, K., & Afsharifar, A. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.107587 · Cited by 4 · see citing works
STUDY OF THE COMPOSITION AND PROPERTIES OF SECONDARY METABOLITES OF THE LICHEN USNEA BARBATA
Лыскова, Н. С., Bazarnova, J. G., & Kruchina-Bogdanov, I. V. (2017) · chemistry of plant raw material · doi:10.14258/jcprm.2018011966 · Cited by 4 · see citing works
Liquid chromatography-high resolution mass spectrometry for the analysis of bioactive natural products
Aydoğan, C. (2020) · Studies in natural products chemistry · doi:10.1016/b978-0-12-817907-9.00012-x · Cited by 4 · see citing works
Predicting group of metabolites available in partially purified tomato leaves extract showing anticancer activity by high performance liquid chromatography (HPLC) and Fourier transform infrared (FTIR)
Chik, W. D. W. (2011) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb11.2736 · Cited by 4 · see citing works
An improved HPLC method for determination of colocynthin in colocynth
Shekarchi, M., Ramezany, F., Ardekani, M. R. S., et al. (2015) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 4 · see citing works
Pharmacological evaluation of South African medicinal plants used for treating tuberculosis and related symptoms.
Madikizela, B. (2014) · ResearchSpace (University of KwaZulu-Natal) · Cited by 4 · see citing works
Oral supplementation of fucoxanthin regulates gene expression in the brain of middle-aged rats
Park, H., Amjad, E. C., Burnett, G., Ferdous, K. A., Scott, M., Jansen, J., Bannerman, S., Scott, M., Correll, R. N., Ciesla, L. M., et al. (2025) · British Journal Of Nutrition · doi:10.1017/s0007114525104996 · Cited by 3 · see citing works
“Similarly, a molecular docking simulation study identified fucoxanthin ’ s inhibitory effects on A β aggregation by its interaction with 16 – 20, 24 – 28 and 33 – 37 residues of A β (58) .”
Pressurized liquid extraction of natural products
Avramescu, S. M., Fierăscu, I., Fierăscu, R. C., & Cudalbeanu, M. D. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-823349-8.00019-8 · Cited by 4 · see citing works
Dereplication and Identification of Natural Products Using LC-NMR Based Strategies
Brkljača, R., Wolfender, J., & Urban, S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-409547-2.14742-0 · Cited by 3 · see citing works
Unveiling plants with food preservative properties
Oladeji, O. S., Alabi, R. O., Oluyori, A. P., & Adelowo, F. E. (2024) · Nutrire · doi:10.1186/s41110-024-00278-3 · Cited by 3 · see citing works
Open column, reversed-phase high-performance liquid chromatography with diode array detection and chemometric strategy for investigation of metabolic fingerprints of complex systems
da Fonseca, R. J., Afonso, S., Bruns, R. E., et al. (2014) · Analytical Methods · doi:10.1039/c4ay01985g · Cited by 3 · see citing works
Coumarins: Analytical and Preparative Techniques
Luca, S. V., Głowniak, K., & Skalicka‐Woźniak, K. (2018) · Encyclopedia of Analytical Chemistry · doi:10.1002/9780470027318.a9925.pub2 · Cited by 3 · see citing works
Razvoj metode za HPLC-analizo izbranih fenolnih spojin lesa
Poljanšek, I., Vek, V., & Oven, P. (2015) · Acta Silvae et Ligni · doi:10.20315/asetl.108.2 · Cited by 2 · see citing works
“liquid, zato LC - liquid chromatography), pri čemer so različne hitrosti potovanja spojin skozi kolono posledica selektivnega zadrževanja (retencije) komponent na stacionarni fazi kolone (Žorž 1991; Waksmundzka-Hajnos and Sherma 2010).”
Background
Isolation of Estuary Soil Fungi and Screening Antibacterial Activity Against Staphylococcus aureus
Rosyadi, A., Triatmoko, B., & Nugraha, A. S. (2022) · Indonesian Journal of Pharmaceutical Science and Technology · doi:10.24198/ijpst.v1i1.28834 · Cited by 2 · see citing works
General overview on SARS-CoV-2 and potential role of natural compounds as antiviral drugs targeting SARS-CoV-2 proteins
Dassamiour, S., Ghebache, W., & Garbi, H. (2022) · Arab Gulf Journal of Scientific Research · doi:10.51758/agjsr-s2-2021-0019 · Cited by 2 · see citing works
Chiral Chromatographic Methods in the Analysis and Purification of Enantiomers
Novell, A., & Minguillón, C. (2013) · doi:10.1002/9781118596784.ssd054 · Cited by 2 · see citing works
HPLC-PDA Analysis of Polyacetylene Glucosides from Launaea capitata and Their Antibacterial and Antibiofilm Properties against Klebsiella pneumoniae
Aljarba, T. M., Bar, F. M. A., Sherif, A. E., et al. (2024) · Pharmaceuticals · doi:10.3390/ph17091214 · Cited by 1 · see citing works
Bioactive Polyacetylenes of Carrots in Cancer Prevention
Christensen, L. P. (2012) · Humana Press eBooks · doi:10.1007/978-1-62703-167-7_29 · Cited by 1 · see citing works
Quantification of methyl esters of fatty acids in the oil of Physalis minima by GC-MS
(2015) · Journal of Coastal Life Medicine · doi:10.12980/jclm.3.201514j92 · Cited by 1 · see citing works
“Qualitative and quantitative evaluation of the chemical constituents is vital for establishing the quality control profile and standardization of herbal extracts[1-6].”
Background
Assessment of Toxicity Issues of Bis-Coumarine Derivates and their Lanthanoid Complexes by Statistical Data Analysis
Milanova, M. (2018) · Biomedical Journal of Scientific & Technical Research · doi:10.26717/bjstr.2018.09.001843 · Cited by 1 · see citing works
“Coumarin (2H-1-benzopyran-2-one) and its derivates are large class of chemical compounds, most of them naturally occurring and can be found in plants [1], fungi and bacteria [2,3] or can be synthesized with a modification of the coumarin ring [4-6].”
Background
Separation of Three Flavones from Chamaecyparis obtusa Using Functionalized Hollow Microsphere Polymers
Tian, M., Bi, W., & Row, K. H. (2014) · Asian Journal of Chemistry · doi:10.14233/ajchem.2014.16680 · Cited by 1 · see citing works
Estudo de alcaloides dos frutos de Passiflora alata e de Passiflora edulis por SBSE, CLAE-Flu e identificação por CLUE-EM
Silva, G. R. (2015) · doi:10.11606/d.75.2015.tde-17082015-143533 · Cited by 1 · see citing works
High Pressure Liquid Chromatography Analysis of Alkaloids
de Oliveira, B. H. (2019) · Encyclopedia of Analytical Chemistry · doi:10.1002/9780470027318.a9921.pub2 · Cited by 1 · see citing works

Authors: Waksmundzka‐Hajnos, M., & Sherma, J.
ORCID: Monika Waksmundzka‐Hajnos
Joseph Sherma
Venue: CRC Press eBooks
Publisher: CRC Press
Published: 2010-11-08
DOI: 10.1201/b10320
OpenAlex: W2117198499
Cited by: 130
References: 0
Citations by year: 2026: 6 · 2025: 8 · 2024: 4 · 2023: 4 · 2022: 13 · 2021: 7 · 2020: 6 · 2019: 12 · 2018: 9 · 2017: 15 · 2016: 5 · 2015: 13 · 2014: 11 · 2013: 5 · 2012: 4
Type: reference entry
Language: en
Open access: closed
Locations: CRC Press eBooks (publishedVersion)
Topics: Physical Sciences › Chemistry › Analytical Chemistry › Chromatography in Natural Products
Health Sciences › Medicine › Complementary and alternative medicine › Traditional Chinese Medicine Analysis
Physical Sciences › Chemistry › Analytical Chemistry › Analytical Methods in Pharmaceuticals
Keywords: HPLC, phytochemical analysis, herbal medicine, plant-derived drugs, phytochemical profiling

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

High Performance Liquid Chromatography in Phytochemical Analysis

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cited by

Related

Record

About these checks