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Molecular Biology of the Cell
Abstract
An introduction to the essentials of the molecular biology of the cell would easily fill this book. Instead I shall focus on one set of problems in molecular biology that Francis Crick, one of the discoverers of the DNA double helix, has termed the central dogma of molecular biology. This central dogma states that there are three types of crucial biological macromolecules, DNA, RNA and proteins, that “communicate” such that genetic information flows in the single direction from DNA via RNA to proteins. Figure 1.1 specifies the different steps of that information flow that we discuss in the following.
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Cited by
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Sorrenti, A., Leira-Iglesias, J., Markvoort, A. J., de Greef, T. F. A., & Hermans, T. M. (2017) · Chemical Society Reviews · doi:10.1039/c7cs00121e · Cited by 574
Bioinks and bioprinting technologies to make heterogeneous and biomimetic tissue constructs
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Paul, A., Crow, M., Raudales, R., He, M., Gillis, J., & Huang, Z. J. (2017) · Cell · doi:10.1016/j.cell.2017.08.032 · Cited by 421
Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity
Alexander, J. M., Guan, J., Li, B., Maliskova, L., Song, M., Shen, Y., Huang, B., Lomvardas, S., & Weiner, O. D. (2019) · eLife · doi:10.7554/elife.41769 · Cited by 346
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Metadata
- Venue
- Biophysics for Beginners
- Publisher
- Jenny Stanford Publishing
- Published
- 2013-12-20
- Pages
- 12-29
- OpenAlex
- W4230524569
- Cited by
- 641
- References
- 0
- FWCI
- 39.27
- Type
- book chapter
- Language
- en
- Open access
- closed
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