The DOI matches its Crossref record; 34 of the 35 references it cites were found in a registry or an index.
Shared and unique contributions of anger, anxiety, and depression to coronary heart disease: A prospective study in the normative aging study
Abstract
Background Anger, anxiety, and depression have each been identified as risk factors for coronary heart disease (CHD). Whether the apparent risk is a function of unique aspects of each emotion or due to a shared underlying dimension of negative affectivity is unclear. Purpose The goal of this study was to assess shared and unique contributions of anger, anxiety, and depression to incident CHD. Methods Data are from the Veterans Administration Normative Aging Study, an ongoing cohort of older men. Measures of anger, anxiety, and depression were obtained from 1,306 men completing the revised Minnesota Multiphasic Personality Inventory in 1986. From these measures we derived three near-orthogonal scales termed iso(lated)-anger, iso-anxiety, and iso-depression and a fourth scale measuring general distress. Results During an average of 10.9 years of follow-up, 161 cases of incident CHD occurred. When considered individually, iso-anxiety, iso-anger, and shared general distress were each associated with CHD risk. When all emotions were considered simultaneously, only iso-anxiety and shared general distress were associated with incident CHD. Conclusions Considering shared versus unique aspects of negative emotions may clarify the nature of their apparent toxicity in relation to CHD risk. General distress shared across negative emotions is an important component in the emotion-CHD relation. Aspects of anxiety may also independently increase CHD risk.
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“However, specific emotional experiences have distinct neurobiological and behavioral features, and they uniquely contribute to CVD risk. 10-13”
From Psychological Health, Well-Being, and the Mind-Heart-Body Connection: A Scientific Statement From the American Heart Association (2021) · cites this paper as [10]
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Yu, X., Wu, H.-T., Hou, Y.-Y., Lan, Y.-Z., Chen, W.-J., & Liu, J. (2025) · Medicine · doi:10.1097/md.0000000000045866
“[19] 22] Both cohort and prospective studies have reported positive correlations between irritability and the incidence of severe acute coronary syndrome, atrial fibrillation, [21] heart failure, [23] and hypertension.”
Dimond, A. J., Krantz, D. S., Waters, A. J., Liew, K. S., & Gottlieb, S. S. (2021) · medRxiv · doi:10.1101/2021.09.14.21263592 · Cited by 1
“Chronic psychosocial risk factors, including depression, hostility, and low levels of social support that predict poor HF outcomes (12-14, 26, 28, 38) are thought to operate through similar mechanisms.”
Background
Metadata
- Authors
- Kubzansky, L. D., Cole, S. R., Kawachi, I., Vokonas, P., & Sparrow, D.
- Affiliations
- Harvard University (US)
- United States Department of Veterans Affairs (US)
- Johns Hopkins University (US)
- Venue
- Annals of Behavioral Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-02
- Volume
- 31
- Issue
- 1
- Pages
- 21-29
- ISSN
- 0742-5554 (ISSN-L)
- 0883-6612
- 1532-4796
- OpenAlex
- W1984742880
- Semantic Scholar
- 8775b99815c14e852ed051a5c0fb4eeda78d621d
- Cited by
- 203
- References
- 35
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 4 · 2023: 4 · 2022: 6 · 2021: 13 · 2020: 7 · 2019: 8 · 2018: 12 · 2017: 11 · 2016: 14 · 2015: 13 · 2014: 12 · 2013: 15 · 2012: 11
- FWCI
- 8.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Behavioral Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Allergy and Infectious Diseases (U01 AI42590, U01AI042590, U01AI035043, U01 AI-35043)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- coronary artery disease, anger, anxiety, depression, negative affectivity, general distress, incident cardiovascular events, older men
- MeSH terms
- Adult, Affect, Aged, Aged, 80 and over, Aging, Anger, Anxiety, Coronary Disease, Depression, Humans, Male, Middle Aged, Prospective Studies, Surveys and Questionnaires, Risk Factors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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