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Physiologically Based Pharmacokinetic Models in the Prediction of Oral Drug Exposure Over the Entire Pediatric Age Range-Sotalol as a Model Drug
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“A two-fold error range (0.5–2.0) was used as a criterion to evaluate the predicted performance for PK parameters [50,51,52].”
From Predicting Food–Drug Interactions between Piperine and CYP3A4 Substrate Drugs Using PBPK Modeling (2024) · cites this paper as [57]
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The Simcyp ® Population-based ADME Simulator
Jamei, M., Marciniak, S., Feng, K., Barnett, A., Tucker, G., & Rostami-Hodjegan, A. (2009) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1517/17425250802691074 · Cited by 533
Johnson, T. N., Rostami-Hodjegan, A., & Tucker, G. T. (2006) · Clinical Pharmacokinetics · doi:10.2165/00003088-200645090-00005 · Cited by 530
Development and Evaluation of a Generic Physiologically Based Pharmacokinetic Model for Children
Edginton, A. N., Schmitt, W., & Willmann, S. (2006) · Clinical Pharmacokinetics · doi:10.2165/00003088-200645100-00005 · Cited by 357
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Cited by
Samant, T., Lukacova, V, & Schmidt, S. (2017) · CPT: Pharmacometrics & Systems Pharmacology · doi:10.1002/psp4.12180 · Cited by 22
Predicting Food–Drug Interactions between Piperine and CYP3A4 Substrate Drugs Using PBPK Modeling
Lin, F., Hu, Y., Zhang, Y., Zhao, L., Zhong, D., & Liu, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252010955 · Cited by 20
Massaux, C., Dogné, J.-M., & Musuamba, F. T. (2026) · European Journal of Drug Metabolism and Pharmacokinetics · doi:10.1007/s13318-026-00988-1 · Cited by 2
Metadata
- Authors
- Khalil, F., & Läer, S.
- Venue
- The AAPS Journal
- Published
- 2014-01-08
- Volume
- 16
- Issue
- 2
- Pages
- 226-239
- ISSN
- 1550-7416
- Cited by
- 74
- References
- 3
- Language
- en
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