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Cited by 561

The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.

The Functions of Corticosteroid-Binding Globulin and Sex Hormone-Binding Globulin: Recent Advances*

ROSNER, WILLIAM·1990·Endocrine Reviews

Abstract

The presence of corticosteroid-binding globulin (CBG) in plasma was detected about 30 yr ago, and of sex hormone-binding globulin (SHBG) about 20 yr ago. In the interval since their discovery, sophisticated binding and RIAs have been devised for their measurement; their concentrations in plasma and other biological fluids, from milk to saliva, have been measured in myriad clinical conditions in humans, and numerous experimental ones in animals; their phyletic distribution has been examined; they have been isolated and their complementary DNAs (cDNAs) cloned; their binding specificities for steroids have been examined in heroic detail; hormonal and drug influences on their plasma concentration in vivo, and their secretion by liver cells in vitro, have been widely explored; they have been the subject of two long, splendid monographs (1, 2) and many shorter reviews (3–11) [wherein the original citations for the first part of this sentence may be found]—and yet we still have not come to a consensus on what it is that they do. Undeniably, they bind certain steroids. But to what biological end?

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Metadata

Authors
ROSNER, W.
Venue
Endocrine Reviews
Published
1990-02
Volume
11
Issue
1
Pages
80-91
ISSN
  • 0163-769X (ISSN-L)
  • 1945-7189
OpenAlex
W2067539975
Cited by
561
References
98
FWCI
22.67
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Functions of Corticosteroid-Binding Globulin and Sex Hormone-Binding Globulin: Recent Advances*. https://app.cochat.ai/papers/10.1210/edrv-11-1-80
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ROSNER, W. (1990). The Functions of Corticosteroid-Binding Globulin and Sex Hormone-Binding Globulin: Recent Advances*. Endocrine Reviews. https://doi.org/10.1210/edrv-11-1-80

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.