The DOI matches its Crossref record.
Gonadotropin-Releasing Hormone Receptors: Structure and Signal Transduction Pathways
Abstract
SEVERAL aspects of the GnRH receptor and its signaling properties and secretory actions have been previously described (1–5). The characterization of GnRH receptors, their physiological regulation, and their relationship to reproductive function were discussed in 1981 (1). The role of Ca2+ as the second messenger, and of diacylglycerol (DAG) as a potential amplifier of the Ca2+ signaling in GnRHstimulated cells, was reviewed in 1986 (2). The molecular mechanism of GnRH action was further discussed in 1988, including the dependence of GnRH-induced secretion on phosphoinositide action (3, 4). Also, signal transduction in GnRH-stimulated cells was reviewed in 1990 as an example of a phospholipid-dependent pathway; the review addressed the interactions between cytoplasmic calcium and protein kinase C (PKC) in the control of gonadotropin synthesis and release, as well as the participation of phospholipase D (PLD), arachidonic acid (AA) and its metabolites in GnRHinduced signaling (5). Since 1990, there has been an explosive increase in information about GnRH receptors and their signaling properties.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
de Roux, N., Young, J., Misrahi, M., Genet, R., Chanson, P., Schaison, G., & Milgrom, E. (1997) · New England Journal of Medicine · doi:10.1056/nejm199711273372205 · Cited by 518
Seminara, S. B., Hayes, F. J., & Crowley, W. F. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.5.0344 · Cited by 414
Gonadotropin-releasing-hormone-receptor antagonists
Huirne, J. A., & Lambalk, C. B. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06797-6 · Cited by 319
GnRH signaling, the gonadotrope and endocrine control of fertility
Bliss, S. P., Navratil, A. M., Xie, J., & Roberson, M. S. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.04.002 · Cited by 259
Kaiser, U. B., Conn, P. M., & Chin, W. W. (1997) · Endocrine Reviews · doi:10.1210/edrv.18.1.0289 · Cited by 254
Metadata
- Authors
- STOJILKOVIC, S. S., REINHART, J., & CATT, K. J.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 1994-08
- Volume
- 15
- Issue
- 4
- Pages
- 462-499
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W1964512812
- Cited by
- 471
- References
- 0
- FWCI
- 28.62
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Gonadotropin-Releasing Hormone Receptors: Structure and Signal Transduction Pathways. https://app.cochat.ai/papers/10.1210/edrv-15-4-462
- The paper
- STOJILKOVIC, S. S., REINHART, J., & CATT, K. J. (1994). Gonadotropin-Releasing Hormone Receptors: Structure and Signal Transduction Pathways. Endocrine Reviews. https://doi.org/10.1210/edrv-15-4-462
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
