The DOI matches its Crossref record; 190 of the 190 references it cites were found in a registry or an index.
Molecular Determinants of Glucocorticoid Receptor Function and Tissue Sensitivity to Glucocorticoids
Abstract
Glucocorticoids play an essential role in maintaining basal and stress-related homeostasis, and lack of glucocorticoid action is incompatible with life in primates. Most known effects of glucocorticoids are mediated by the intracellular GR. The magnitude of a cell's response to glucocorticoids depends both on the hormone level it is exposed to and on its glucocorticoid sensitivity, i.e. the efficiency of GR-mediated signal transduction. In this review, we have summarized the multiple endogenous and exogenous factors that have been shown to be involved in this signaling cascade and, thus, to alter glucocorticoid sensitivity.
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Cites
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Cited by
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Self-citation
Metadata
- Authors
- BAMBERGER, C. M., SCHULTE, H. M., & CHROUSOS, G. P.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 1996-06
- Volume
- 17
- Issue
- 3
- Pages
- 245-261
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W2005668937
- Cited by
- 889
- References
- 190
- FWCI
- 23.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- BAMBERGER, C. M., SCHULTE, H. M., & CHROUSOS, G. P. (1996). Molecular Determinants of Glucocorticoid Receptor Function and Tissue Sensitivity to Glucocorticoids. Endocrine Reviews. https://doi.org/10.1210/edrv-17-3-245
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.