Estrogen Increases Locomotor Activity in Mice through Estrogen Receptor α: Specificity for the Type of Activity

Ogawa, Sonoko; Chan, Johnny; Gustafsson, Jan-Åke; Korach, Kenneth S.; Pfaff, Donald W.

doi:10.1210/en.2002-220519

Estrogen Increases Locomotor Activity in Mice through Estrogen Receptor α: Specificity for the Type of Activity

Estrogens are known to increase running wheel activity of rodents primarily by acting on the medial preoptic area (mPOA). The mechanisms of this estrogenic regulation of running wheel activity are not completely understood. In particular, little is known about the separate roles of two types of e…